Innovation at the intersection of cardiothoracic surgery and machine learning.

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Hiesinger Lab retweeted
Excited to share that EchoAI-Peds is now published at Circulation! @CircAHA ahajournals.org/doi/10.1161/…
We are excited to announce 🔥EchoAI-Peds 🔥, the first multi-task deep learning model for pediatric #echofirst analysis. It's been a pleasure to lead this alongside @mrudangm14 under the guidance of @hiesingerlab and in close collaboration with @jolleylab. Link below⬇️ [1/n]
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🎉 Congrats to Dr. William Hiesinger, Assoc Prof of Cardiothoracic Surgery, who received the Cardiac Biology Club Cup 🏆 presented by the @AATSHQ! He was given the award at the AATS 106th Annual Meeting, which was held in Chicago in May.✨ @HiesingerLab med.stanford.edu/ctsurgery/a…
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Hiesinger Lab retweeted
Happy to report that our work on building foundation models for Cardiac MRI has finally been published in Nature Biomedical Engineering! @natBME nature.com/articles/s41551-0…
I’m excited to finally showcase our work on developing a generalizable deep learning system for cardiac MRI. This is the culmination of over 3 years of research spanning my time as a postdoc in @HiesingerLab and now as a cardiac surgery resident at @pennsurgery, and I couldn’t be happier with the finished product. Weights to be released for academic use (coming soon!). All built with @pytorch and @pytorch_lightning. Lots of really cool stuff to unpack, but here are few main results: Contrastive learning with cine-sequence CMR studies from multiple different views (short axis, 2-chamber, 3-chamber, and 4-chamber views) with long-form CMR free text reports is really hard. A good sign for us was how the video transformer embeddings evolved with each epoch. We train for about 600 epochs taking about 2 weeks. In a zero shot fashion, the model can then do some really interesting things: separate out different diseases (ACDC dataset), and different genders, age groups, and ejection fractions (UK BioBank) with no explicit supervised instruction. No such behaviour with kinetics-600 initialized weights (see preprint)! Finetuning over our system yields results superior to baseline approaches on downstream tasks of interest, with 10x and sometimes 100x less data. Here’s a quick figure showing how we achieve superior results for UK BioBank LVEF estimation with just 1% of the available data. Better yet, that same model when tested on a Kaggle dataset does exceptionally well (dashed line = kinetics-600 performance on left; lower is better!). Focusing on some disease diagnosis tasks, we label a separate dataset of some 6000 individual patients. This is real-world representative unenriched dataset. Our methods show massive improvements in AUC compared to baseline methods. Validation set shown here, internal test set (Stanford / Medstar / UCSF), and external test set (UPenn) figures are in the paper.
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Hot off the press! ✨ New paper looking at a generalizable deep learning system for cardiac MRI🫀. Led by @StanfordMed @HiesingerLab researchers and collaborators.✨ @Penn @UCSF @rohanshad @cyrilzakka @dhamank24 @mrudangm14 @StanfordDeptMed @StanfordVasc ow.ly/L6UE50YyOiy
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Honored to share our work on AI-powered, biomechanical simulators for robotic surgery at the #AHAResearchRoundtable today! Big thanks to @AHAScience for supporting this vision ❤️🤖
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✨Congrats to our incoming @StanfordCTSurg integrated residents! 🎉 We're excited to have three new interns joining our program: Daniel Alber of @nyugrossman, Oluwademilade Tega of @ColumbiaPS, and Brandon Wesley of @StanfordMed - welcome to the team!🌲#WeAreStanford #Match2026
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Hiesinger Lab retweeted
We are excited to announce 🔥EchoAI-Peds 🔥, the first multi-task deep learning model for pediatric #echofirst analysis. It's been a pleasure to lead this alongside @mrudangm14 under the guidance of @hiesingerlab and in close collaboration with @jolleylab. Link below⬇️ [1/n]
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✨Featured Article ✨in @atvbahajournals May issue! Chemokine (C-C motif) Ligand 2 Expressing Adventitial Fibroblast Expansion During Loeys-Dietz Syndrome Aortic Aneurysm Formation. Authors inc. @ardalal_MD @ajpedroza_md @HiesingerLab, Fischbein Lab, et al ow.ly/B3vJ50VNheY
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A huge congratulations to super-🌟 med student and @HiesingerLab member @dhamank24! 🥳
✨Congratulations to our incoming @StanfordCTSurg integrated residents! 🎉 We're excited to have three new interns joining our program: Dhamanpreet Kaur of @StanfordMed, Arian Mansur of @harvardmed, & Alice Zhou of @HopkinsMedicine- welcome to the team!🌲#WeAreStanford #Match2025
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Hiesinger Lab retweeted
I’m making the model weights for our foundational CMR vision encoders (see pinned post) available free for academic use. Paper still in peer review, but can’t wait to see what everyone builds with this! Git: github.com/rohanshad/cmr_tra… Weights: huggingface.co/rohanshad/cmr… #HNY2025
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The Hiesinger Lab @stanfordctsurg is at #AHA24! Catch lab members @rohanshad and @dhamank24 presenting their work on uncovering hidden HCM diagnoses in the UKBioBank using deep learning for CMR🫀🧲💻🤖 Where: S104A When: 4:00 - 4:10 pm (CT), Nov 17
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Hiesinger Lab retweeted
Had a great time talking about finite elements and generative AI in medicine at @BmeSjsu Pathways Seminar last week! Many thanks to my dear friend Prof. @EllaSugerman for the invite and to my @HiesingerLab mates @joseph_cho1 and @cyrilzakka for sharing their great results 🔥
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🔥New preprint alert🔥 We're excited to share an early preview of 𝗦𝘂𝗿𝗚𝗲𝗻, a text-diffusion model for generating surgical videos! This model can generate videos of higher quality (720x480) & longer duration (49 frames) than the current SoTA. Great work by @joseph_cho1!
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Hiesinger Lab retweeted
Two years ago to the day, I joined the @HiesingerLab at Stanford Medicine, and now it’s time for me to wrap up this chapter of my life! 🎓 Reflecting back, I see a tapestry of efforts—my family's unwavering support, my friends’ continuous encouragement, my own growth—and some luck along the way. It truly does take a village, and I'm grateful for every part of mine. It goes without saying that I’m grateful to both @rohanshad and @HiesingerLab for believing in me every step of the way, and always encouraging me to lead my own projects and find my own voice, despite many of the obstacles we faced. I’m also lucky to have met some truly impactful people whose work over the years has heavily influenced my own research direction, many of whom have also taken it upon themselves to guide me along the way, namely @Dr_ASChaudhari @RoxanaDaneshjou @curtlanglotz @DrAalami @pranavrajpurkar @euanashley @ardalal_MD and many more! Excited for what’s next!
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Hiesinger Lab retweeted
In case you missed it, our team in collaboration with @Dr_ASChaudhari, @RoxanaDaneshjou, @DrAalami, and @vishnuravi defined a framework for autonomous EHR systems, and implemented the first Level 1 EHR system with retrieval and extractive capabilities! Check it out!
Super excited to showcase our newest work Almanac Copilot an EHR agent capable of answering questions about your patients and placing orders for you across any modern EHR system. Background: Nearly 75% of clinicians with burnout symptoms pinpoint EHRs as a source due to poor usability or workflow integration. Methodology: We train a 33B LLM to perform open-ended QA on patient information, as well as order placement using the FHIR interoperability standard (cc @zakkohane , @AdamRodmanMD) Result: Almanac Copilot obtains a success rate of 74% across 300 common EHR tasks based on MIMIC-IV. Your very own personal EHR assistant!
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Hiesinger Lab retweeted
I’m giving a few talks on GenAI in Health in the next few months to technical founders and practicing clinicians across the US. Would love to highlight some open source medical AI projects in my slides and am looking for some suggestions. /cc @Michael_D_Moor @katieelink
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Catch our postdoc @cyrilzakka presenting our work on Almanac at the @StanfordHAI Five event today! Also a great lineup of speakers!
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Hiesinger Lab retweeted
Introducing MediSyn, a pair of text-guided diffusion models for generating high-fidelity and diverse medical 2D and 3D images across medical specialties and imaging modalities. arxiv.org/abs/2405.09806 1/n
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Hiesinger Lab retweeted
Exciting week! We're also releasing an early preview of MediSyn, a family of text-diffusion models exploring the potential for generative models to synthesize medical data across many modalities (2D and 3D) and specialties (dermatology, radiology, pathology, GI, ophthalmology, surgery and more) We're still exploring different techniques to improve text alignment and generation quality but this is a great first step!
Introducing MediSyn, a pair of text-guided diffusion models for generating high-fidelity and diverse medical 2D and 3D images across medical specialties and imaging modalities. arxiv.org/abs/2405.09806 1/n
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Hiesinger Lab retweeted
Super excited to showcase our newest work Almanac Copilot an EHR agent capable of answering questions about your patients and placing orders for you across any modern EHR system. Background: Nearly 75% of clinicians with burnout symptoms pinpoint EHRs as a source due to poor usability or workflow integration. Methodology: We train a 33B LLM to perform open-ended QA on patient information, as well as order placement using the FHIR interoperability standard (cc @zakkohane , @AdamRodmanMD) Result: Almanac Copilot obtains a success rate of 74% across 300 common EHR tasks based on MIMIC-IV. Your very own personal EHR assistant!
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