Levels@Levels

Levels helps you see how food affects your health.

levels.link/bio
Joined July 2019
431 Photos and videos
Why did moderate drinkers look so healthy for decades? Many supposed “abstainers” in alcohol studies were actually former drinkers, including people who quit because they were sick. That comparison can make moderate drinking look artificially protective.
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Alcohol is a Group 1 carcinogen. That doesn’t mean its risk equals cigarette smoke or asbestos. It means the evidence that alcohol can cause cancer meets the highest standard of causal evidence. Tim Naimi explains. 📺 Watch on YouTube: piped.video/8GNmcjPfg7U
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Tony Wyss-Coray’s team gave young blood to old mice. Their brains showed better memory, new neurons, less inflammation, and more synaptic connections. The implication: factors in blood may actively influence aging, rather than merely reflect it.
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Alzheimer’s can begin 20–30 years before symptoms. Tony Wyss-Coray is studying whether blood proteins can reveal that kind of hidden risk earlier. In one analysis, every extra 4.1 years of estimated heart age was linked to nearly 2.5× heart-failure risk.
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One part of your body may be aging faster than the rest. Across 50,000 people, Tony Wyss-Coray’s team often found one standout “weakest link,” potentially pointing toward the disease that person may be most vulnerable to later. 📺 Watch on YouTube: piped.video/1dfMBAZiP8o
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Aging may happen in waves. Tony Wyss-Coray’s team found large shifts across hundreds to thousands of proteins around certain periods of life, suggesting aging may have measurable biological inflection points rather than proceeding at one steady rate. #aging #proteomics
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A biological-age test can tell you that you appear older or younger. It may not tell you which underlying mechanisms of aging actually changed. Nir Barzilai explains why that gap matters if we want to use these tests to judge whether longevity interventions work.
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Some existing drugs may be doing more than treating one disease. Nir Barzilai points to metformin, SGLT2 inhibitors, GLP-1s, and some osteoporosis drugs as geroscience candidates because their effects extend across multiple age-related conditions. #aging #longevity
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The appealing version of longevity isn’t more years spent sick. Nir Barzilai’s centenarian research found unusually long healthspan followed by a much shorter period of illness near the end of life. That’s “compression of morbidity.” #longevity #healthspan
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Why do genetic risks for diseases like Alzheimer’s sit quietly for decades before disease appears? Nir Barzilai argues aging biology helps unlock that risk, which is why geroscience aims to target the aging process itself. 📺 Watch on YouTube: piped.video/HbeGjwCw6vk
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More health data could mean fewer unnecessary tests. A nodule seen once can trigger a CT or biopsy. Ten years of data showing it never changed tells a very different story. Ziad Obermeyer explains why longitudinal measurement can help separate signal from noise.
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Ziad Obermeyer says healthcare is entering a “mainframe to PC” transition. More biological data can now be collected cheaply outside hospitals. Add AI that can interpret it continuously, and the center of healthcare may start moving toward the patient. #AI #wearables
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Why doesn’t heart disease create the same urgency as cancer? Dr. Ami Bhatt says patients are often told they have risk factors, then left to manage them quietly for years. By the time medicine truly mobilizes, disease may already be established.
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Most medical AI is trained to copy doctors. Ziad Obermeyer’s team trained an algorithm to learn from patients instead, and it found knee pain radiologists were missing. His point: AI gets much more interesting when existing doctors stops being the answer key. #AI #medicalAI
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Every year, 400,000 people drop dead of a heart attack - many weren’t known to be at risk. Ziad Obermeyer’s AI found a high-risk group using ECG data, and 85% weren’t flagged by current clinical criteria. The warning signal was already there. Medicine hadn’t learned to see it.
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piped.video/WDo-iL6O5nU

Why Medical AI Is Aiming Too Low | Dr. Ziad Obermeyer & Mike Haney

Medical AI is already getting good at doing things doctors do. Dr. ...

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GLP-1 drugs have a strange trick: they kill the urge to keep eating without killing the enjoyment of eating. Neuroscientist Dr. Dana Small says that wanting-vs-liking split is probably why people are willing to stay on them. 📺 Watch on YouTube: piped.video/lXlCqNqjgHY
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Can calling a food "a treat" change your biology? Yes. In a Yale study, people who believed they'd drunk an "indulgent" milkshake felt more satisfied (bigger drop in ghrelin) than people told it was "sensible" — identical drink both times.
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Probiotics get all the attention. But the real benefit comes from what they produce—postbiotics. Dr. Will Bulsiewicz explains how prebiotics + probiotics = short-chain fatty acids that support gut and metabolic health. #guthealth #probiotics #postbiotics #metabolichealth
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Sugar's real reward isn't the sweetness. Neuroscientist Dr. Dana Small: the signal fires after you swallow, when your gut senses glucose as fuel. Block it, and the craving vanishes, even if it still tastes sweet. 📺 Watch on YouTube: piped.video/lXlCqNqjgHY
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