The official journal of @ASTCT.
- Tweets 1,340
- Following 60
- Followers 4,330
- Likes 2,508
Study found that coronary artery calcification identified during pretransplant evaluation predicted non-relapse mortality in patients receiving PTCy. Among elderly patients without known coronary artery disease, it was associated with inferior survival. ow.ly/p4rP50ZPM6U
2
4
366
Read on updates to the 2012 ASBMT acute #GVHD guidelines, including consensus recommendations on acute GVHD staging and grading, the clinical role of biomarkers and risk-stratification tools and acute GVHD treatment. astctjournal.org/article/S26…
6
20
1,448
This real-world analysis found that prophylactic anakinra did not reduce grade ≥3 #CART associated neurotoxicity syndrome. No survival or response rate differences observed with anakinra prophylaxis. Read: astctjournal.org/article/S26…
1
2
376
This study provides first evidence linking Lnc-BRMS1L-4 and ZEB1-AS1 to acute lymphoblastic leukemia and clinical features. Read the full study: astctjournal.org/article/S26…
198
The September issue of 'Transplantation and Cellular Therapy,' is now available online: astctjournal.org/current
@ELShematology
1
610
This study found a 6.8% 10-year incidence of non-cutaneous secondary malignancies after #HCT confirming their impact on late nonrelapse mortality. PTCy-based #GVHD prophylaxis was not associated with increased solid tumor risk. Read: astctjournal.org/article/S26…
4
461
This analysis highlights the substantial physical mental and emotional burden of chronic #GVHD on patients and caregivers. Posts also described inability to work high treatment costs and distinct challenges for caregivers of pediatric and adult patients. astctjournal.org/article/S26…
1
3
396
This GATMO-TC experience found 3-year overall survival exceeded 85% after haploidentical HCT for severe aplastic anemia and exceeded 90% with upfront haplo-HCT. Graft failure occurred in 4.5% of patients. Read more: astctjournal.org/article/S26…
9
9
1,480
This two-center study found that earlier defibrotide initiation within 2 days of SOS/VOD diagnosis was associated with improved survival after #alloHCT in adults. Dialysis requirement was associated with poorer outcomes. Read more: astctjournal.org/article/S26…
1
7
728
This long-term follow-up study found that CD19 #CART therapy yielded sustained remissions in R/R B-NHL. High tumor Ki-67 was a poor prognostic factor and was associated with limited CAR-T cell expansion, especially CD8+ cells. Read: astctjournal.org/article/S26…
3
5
469
This systematic review and meta-analysis found that primary ovarian insufficiency and amenorrhea affect 72% and 70% of female #alloHCT survivors. Genital chronic #GVHD occurs in 36% sexual dysfunction in 42% and post-transplant pregnancy in 12%. Read: astctjournal.org/article/S26…
2
4
431
This review highlights implementation challenges for value-based contracts in cell and gene therapies. Outcome selection and data tracking remain key barriers while treatment center workflows can support consistent reliable outcome tracking. Read: astctjournal.org/article/S26…
2
433
This study highlights that early #HSCT for infantile osteopetrosis can lead to better quality of life. Genetic testing is essential as certain mutations are not indicated for HSCT. Read the full study: astctjournal.org/article/S26…
1
1
222
Dose adjustment may be necessary in post #HSCT gilteritinib maintenance therapy. Gilteritinib can be a beneficial maintenance treatment for relapsed or refractory FLT3-mutated acute myeloblastic leukemia after HSCT. Read the full study: astctjournal.org/article/S26…
2
11
1,663
Second primary hematological malignancies (SPHMs) after multiple myeloma (MM), chronic lymphocytic leukemia or lymphoma show poor outcomes and high-risk genomic features. Early genomic assessment may support risk stratification strategies. Read: astctjournal.org/article/S26…
4
453
This study finds that NK cell dose correlates with AML patient survival in univariate analysis of microtransplantation. These findings provide insights for optimizing adoptive NK and T cell immunotherapies. Read more: astctjournal.org/article/S26…
1
2
578
In this issue of Transplantation and Cellular Therapy, AlSaedi and colleagues and Khan and colleagues add longitudinal experience to the literature on #HSCT for malignant infantile osteopetrosis (MIOP). Read the full article: astctjournal.org/article/S26…
543
The August issue of 'Transplantation and Cellular Therapy,' is now available online: astctjournal.org/current
@ELShematology
403
This study shows that post-transplant cyclophosphamide is feasible in HLA-matched #HCT for pediatric hematologic malignancies. Patients achieved 100% engraftment with no acute #GVHD in related donor transplants and no chronic GVHD. astctjournal.org/article/S26…
2
3
679
This review highlights that FACT accreditation is achievable in low- and middle-income countries through cost-effective, adaptable strategies. The authors provide a practical framework for sustaining high-quality HSCT programs. astctjournal.org/article/S26…
2
5
560