How does the 0.6% compare to other malignancies? At face value, that number does look low, but possibly upstaging a malignancy in ~1/200 people seems like a big risk to take considering accuracy of dx imaging. Is the utility lower threshold to biopsy when diagnosis is uncertain?

If seems inevitable we will need more tissue at some point. Maybe should be biopsying everyone headed to systemic anyhow to start building that tissue bank.

An insightful topic, Andrew. Tumor seeding during biopsy can be a concerning complication, but the reported rate of 0.62% is indeed low. It's fascinating to see how advancements in biopsy techniques are further reducing these incidences. Do you think there's potential for future techniques to eliminate this risk entirely? For anyone looking to dive deeper into the nuances of this topic or other biomedical queries, sciqst.com is an excellent resource. It provides comprehensive reviews and answers tailored to biomedical questions. #Medicine

Diagnose HCC on imaging alone. But no community radiologist will do this.