#MondayTip 🧠AF-related ischemic stroke 🫀 #CATALYST pooled 4 RCTs and supports early DOAC initiation (≤4 days) in selected patients, reducing recurrent events without more symptomatic ICH. 👉 Use imaging + bleeding risk, not a rigid calendar doi.org/10.1016/s0140-6736(2…

#MondayTip 💧Net water uptake🧠 #NWU quantifies early edema on noncontrast CT, adding information on tissue injury beyond lesion extent 📈Higher NWU→greater edema & tissue vulnerability ☝️Promising, but not yet a standalone treatment-selection tool 🔗doi.org/10.3389/fneur.2025.1…

📬 The #WSA July Newsletter is out! 🧠 Acute Stroke #Imaging Masterclass 📅 New webinars 🎙️ Podcasts on #AF after stroke #AFDAS & illicit substances 📄 Paper of the Month on Global Stroke #Rehab standards 💡 #MondayTips & more Read it here: world-stroke-academy.org/new…

#WeekendLecture #CarotidArteryDisease #CAD #CAD causes ~ 10-20% of #strokes Atherosclerosis occurs most frequently at carotid #bifurcation, an area of low vessel-wall shear stress and oscillatory/turbulent blood flow Welcome to this mini review!

#STROKE Guidelines in Action 🗒️: In patients with unknown onset or beyond 4.5h, advanced imaging identifying salvageable tissue supports thrombolysis and is associated with better 90-day functional outcomes. ahajournals.org/doi/full/10.…

This narrative review provides a visually driven, clinically grounded roadmap that links dopaminergic neurochemistry and pathway anatomy to in vivo molecular imaging, with a specific focus on education and bedside application: hubs.la/Q0486rSm0

🧠💉 In TNK-treated LVO stroke patients eligible for EVT, thrombus migration occurred in 36% and made EVT impossible in 26% vs 4% without migration. Thrombus migration significantly reduced rates of complete reperfusion but did not affect functional outcomes. Read more here: bit.ly/4lpk658 @jildazz

Greco, A, Occhipinti, G, Giacoppo, D. et al. Antithrombotic Therapy for Primary and Secondary Prevention of Ischemic Stroke: JACC State-of-the-Art Review. JACC. 2023 Oct, 82 (15) 1538–1557. doi.org/10.1016/j.jacc.2023.…

#MRI for #neurologist is a "Acronym Jungle." 🌿 The same scan has ⓷ different names depending on the vendors: Siemens, GE, Philips. Let’s decode the "Big 3" and help you traverse it from a #Neurology POV. 🧵| 8

What exactly is #AFib burden? 🤔 It’s a term widely used in arrhythmia research—but still without a unified definition. #AFib burden can describe: ▪ symptoms during AF ▪ clinical consequences (stroke, HF) ▪ socio-economic impact ▪ or most commonly today — the proportion of time a patient spends in AF Continuous monitoring (CIEDs, wearables) is reshaping how we measure AF burden and revealing that not all AF is the same. Two patients may have identical AF burden but different patterns: 🎵 “Legato” – few long episodes 🎶 “Staccato” – many short episodes Understanding these differences may be key for risk prediction and treatment decisions. 🔖 More on this in #EHRA_ESC Consensus Document of #AFib burden bit.ly/40bOzKg #EHRAtopicweek

I’m proud to share our seminar on Atrial Fibrillation, just published in @TheLancet It was a privilege to be invited to work on this review, which was expertly led by Deirdre Lane, and involved Giuseppe Boriani, Elena Arbelo, Jeroen M Hendriks, So-Ryoung Lee, Greg Lip, Jonathan Mant, Melissa Middeldorp sciencedirect.com/science/ar…

#MondayTip Cancer-related stroke ≠ routine ESUS ~50% of strokes in active cancer are cryptogenic, but many are cancer-driven hypercoagulable events 🔁14–29% recur at 1 year ⚖️Anticoag vs aspirin? Still equipoise 🧠Classify. Risk-stratify. Individualize doi.org/10.1161/str.00000000…

From the newly published 2026 acute pulmonary embolism guideline: PE represents a wide spectrum of presentations, ranging from asymptomatic disease to cardiogenic shock and cardiac arrest. Accordingly, PE necessitates swift and precise risk assessment to determine prognosis, guide therapeutic decision-making, and improve patient outcomes The Acute PE Clinical Categories are designed to describe the severity and prognosis of PE by integrating various clinical, laboratory, and imaging parameters. Category A-E and subcategory 1-3 designations are selected according to the most severe clinical, laboratory, and imaging indicators. Of note, patients may transition among such categories as they are reassessed over time. ✍🏼 @GoldbergJBCTMD @Dkadiandodov @RosovskyRachel @sabeedak1 @hjcox_pvd @JunLiMD @mnyoung1

Secondary Prevention after Ischemic Stroke | New England Journal of Medicine nejm.org/doi/full/10.1056/NE…

Anticoagulation therapy is the foundation of acute PE management. Use of DOACs and LMWH allow for rapid and predictable anticoagulation therapy in most patients with acute PE. Further management strategies are dictated by individual risk factors for adverse events. These include the measurement of biomarkers, RV size and function on imaging, and hemodynamics. Informed by these risk factors, decisions can be made about the utility of advanced interventions, including catheter-directed thrombolysis, mechanical thrombectomy, surgical embolectomy, and extracorporeal membrane oxygenation. Use of a PERT to facilitate decision-making around acute interventions is recommended. ✍🏼 @GoldbergJBCTMD @Dkadiandodov @RosovskyRachel @sabeedak1 @hjcox_pvd @JunLiMD @mnyoung1

New paper in @GreenJournal 📄 The cerebellum has long been a neutral territory in CAA diagnostics, despite growing evidence of cerebellar involvement. We propose pragmatic criteria for identifying CAA-associated cerebellar ICH. 🧠🩸 neurology.org/doi/10.1212/WN… 📜🔍

Snapshot of ISC26 highlights before the @SuperBowl and @sanbenito kick off #ISC2026 @AHAScience @JohannaSeidenMD

🔥🔥MeVO RCT summary ❌❌❌✅✅ #ISC2026 @SposatoL @WorldStrokeEd @SVINJournal @WorldStrokeEd @EdmontonStroke @StrokeAHA_ASA @ShadiYaghi2

🔥 Intravenous thrombolysis in late window (4.5-24 hs) Prior and #ISC2026 data! @SposatoL @ShadiYaghi2 @EdmontonStroke @interneurona @WorldStrokeEd