🦠 Just published in Bioinformatics Advances: "Identification and characterization of bacterial repeat-in-toxin adhesins using long-read genome analysis"  Find it here: doi.org/10.1093/bioadv/vbag2…
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A long-read pipeline with MMseqs2 clustering, InterProScan, and AlphaFold3 modeling identified 35 RTX adhesin isoforms across 16 loci in seven bacterial pathogens. Ligand-binding domains include carbohydrate-binding modules and von Willebrand Factor A-like domains in mix-and-match arrangements.
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