BochmanLab@BochmanLabIU

Biochemistry lab interested in the roles of DNA helicases in maintaining genome integrity...and beer.

 Simon Hall MSB1, 4th floor
indiana.edu/~helicase/
Joined February 2015
41 Photos and videos
Remember not getting a Teddy Ruxpin as a child and realizing that your parents hate you?
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Replying to @kennadi_shu
@kennadi_shu and @BochmanLabIU present in vivo and in vitro analyses of N-terminal domains-truncated isoform of Hrq1. Learn more in #G3journal how understanding this #yeast Hrq1 helicase alleles will help explain why the mutations cause disease in humans. buff.ly/XJLDyoO
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Check out our new paper about Cdc13 hopping between ssDNA substrates: academic.oup.com/nar/advance…

Cdc13 exhibits dynamic DNA strand exchange in the presence of telomeric DNA

Abstract. Telomerase is the enzyme that lengthens telomeres and is tightly regulated by a variety of means to maintain genome integrity. Several DNA helica

academic.oup.com
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Many thanks to the @IU_IAS for giving us some funding to work with @BrianCalvi and @laggingstrand this year.
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We're happy to officially welcome new PhD students Noof Alsulaiti and Kennadi Shumaker to the Bochman Lab!
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We've got a new preprint up on @biorxivpreprint demonstrating dynamic DNA binding by Cdc13. Check it out here (biorxiv.org/content/10.1101/…) or listen to an audio summary on @Science_Cast (sciencecast.org/casts/ed7asr…). #yeast

Cdc13 exhibits dynamic DNA strand exchange in the presence of telomeric DNA

Telomerase is the enzyme that lengthens telomeres and is tightly regulated by a variety of means to maintain genome integrity. Several DNA helicases function at telomeres, and we previously found...

biorxiv.org
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Pumpkin carving in collaboration with @Biolluminator's lab. The black cat carved by Biochem rotation student Kennadi Shumaker was voted 1st prize by my kids.
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More good news: the NIH funded @Doc_Boc's equipment supplement application, and we're getting a @refeynit mass photometer! #booyah
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Congrats to @Doc_Boc for winning the @Ostrom_Workshop Food and Agrarian Systems Natural Sciences Research Impact Award for the lab's work on fermentation science. #yeast
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Wow, today is the 10th anniversary of the lab! Time flies when you're sciencing.
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Spencer and David wowing @brookscrickard1 at the FASEB Helicase poster session. #HNASRC
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Does anyone have problems folding oligos into G4 structures when using near-IR labels from IDT?
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Recently graduated @IUBiotech MS student (and soon to be @GCDB_IU PhD student) Noof Alsulaiti was awarded a full scholarship from the UAE to fund her dissertation work!
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Undergrad David Sun was awarded an @IUBloomington Engaged Learning Travel Grant to attend the @FASEBorg Helicase Meeting this summer. #HNASRC cvent.me/ED8rGV?sms=2
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Undergraduate researcher Morgan Roush was awarded an @NIH Administrative Supplement to Support Undergraduate Summer Research Experiences! #booyah
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We've got a team from @refeynit demonstrating the Refeyn TwoMP mass photometer in lab today. Every biochemist should have one of these. #truth
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Congratulations to grad student Kait Taylor who was awarded a John R. and Wendy L. Kindig Fellowship for 2023 at @IUBloomington!
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Rob doing us proud at his poster #YCB2022
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We were just awarded an @NIH S10 grant to buy a @LUMICKS_nl C-Trap! Thanks to the Aoki, Bell, @Biolluminator, Dalia, Niu, Schlebach, Takagi, Wang, and Zlotnick labs at @IndianaUniv for their help putting the application together.
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We know you want to dip your toes into helicase biochemistry, so here's a short primer on how to get started: authors.elsevier.com/a/1et-0…
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