Brian V. Geisbrecht Laboratory at K-State. We use physical biochemistry methods to study the innate immune system. Papers not preprints.
Manhattan, KS USA
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Congratulations to Ying Zhang on the recent defense of her dissertation research concerning bacterial evasion of antibody mediated immune responses.
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Many thanks to Jacob, Brewmaster of @aggievillebeer in #MHK for sharing his knowledge of the science behind beer making with @KStateBMB #Biochemistry and Society students this morning!
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Congratulations to @HuiquanDuan for a successful defense of his PhD dissertation research on mechanisms of #complement inhibition! @KStateBMB
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“from one stage to the next a greater amount of proenzyme is activated, and it may be suggested that the need to link the minute physical stimulus of surface contact with the final enzymatic explosion has resulted in the evolution of a biochemical amplifier” -RG Macfarlane, 1964
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First description of the self-amplifying nature of the #complement alternative pathway. Muller-Eberhard & Gotze, J. Exp. Med. 1972
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Congratulations to @Nitin_B_Mishra for a successful defense of his PhD dissertation research on #Staph protease inhibitors. @KStateBMB
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What is on your mind? It should be easy to remember where I parked at the airport when traveling to the @AegeanConf Complement Therapeutics meeting. @Conferex
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Dont let the poor angle fool you...@KStateBMB had a great crowd today as we hosted @BourneLabOU to hear about their exciting work on toxin/antitoxin systems that affect DNA gyrase activity in bacteria.
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Congratulations to Dr. Xin Xu @ocharlotte1990 (center) on the successful defense of her dissertation research into #complement components Factor B and Factor H. Best of luck as you move on from @KStateBMB to a permanent staff position with Bristol-Myers Squibb.
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Our manuscript describing DNA #aptamers that inhibit the function of #complement factor B is highlighted on the cover the Feb15th issue of @J_Immunol. A special thank you to @KStateBMB PhD candidate @ocharlotte1990 and our collaborators @SomaLogic for making this possible.
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I saved this piece of advice and taped it on the computer that controls our crystallization robot. That's the perfect home for this message!
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#Kansas is known for its sunsets, but today we have an amazing sunrise beginning an early fall day.
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Our work on inhibition of #neutrophil Cathepsin-G by S. aureus EapH1 is highlighted on the cover of the May 29 issue of @jbiolchem. Thanks to the talented @geisbrechtk from @kstatejmc for this excellent cover design! Another example of the diversity of skills within @KStateArtSci
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KSU Distinguished Professor Mike Kanost gave wonderful talk today in recognition of his receipt of the Commerce Bank and W.T. Kemper Foundation Graduate Faculty Award. Great perspective on unique #manduca insect models of innate immunity. @KState_RSCAD @KStateArtSci @kstateag
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We had the pleasure of hosting @Freudlab from @KUMedCenter today in our weekly seminar series. An excellent discussion of the structure and mechanism behind #telomerase fidelity!
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As if we needed more reasons to appreciate physical chemistry, I give you this. #HappyNewYear #winter
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Marketing like this is only possible when the consumer is scientifically illiterate. What pH is this water when it enters the GI tract? Also, measuring something in nanograms doesn't mean you are using nanotechnology. #thinkbeforeyoubuy
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SDS solutions don't precipitate at standard state. Please @KState facilities, turn up the heat in Burt Hall.
