Cell@CellCellPress

Cell aims to publish the most exciting and provocative research in biology. Posts by Scientific Editors on the Cell Editorial team.

 Cambridge, MA
cell.com/cell/editors-and-st…
Joined August 2009
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Cell@CellCellPress
Sep 17
Our Special Issue on AI in Biology is out 👉cell.com/cell/current The cover introduces LongevityBench, an open benchmark comprising 17 tasks across five biodata domains to evaluate AI systems in the context of human aging.
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Now online! CD4 T cells convert transient responses to KRAS inhibition to durable remissions in pancreatic cancer dlvr.it/TVfMY5

CD4 T cells convert transient responses to KRAS inhibition to durable remissions in pancreatic...

An AI-designed IL-21 mimetic converts transient KRAS inhibitor responses into durable pancreatic cancer remissions through CD4 T cells, independent of CD8 T cells and tumor MHC class I expression.

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Now online! Switching of transcriptional control from interferon regulatory factor 2 to interferon regulatory factor 1 drives innate immune cell activation dlvr.it/TVfGC2

Switching of transcriptional control from interferon regulatory factor 2 to interferon regulatory...

Toll-like receptor signaling activates proinflammatory interferon-stimulated genes (ISGs) even in the absence of interferon by triggering a shift from IRF2 to IRF1 occupancy at ISG promoters and...

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Now online! A geothermal amoeba sets a new upper temperature limit for eukaryotes dlvr.it/TVf3dr

A geothermal amoeba sets a new upper temperature limit for eukaryotes

The amoeba Incendiamoeba cascadensis demonstrates that eukaryotic life can withstand temperatures beyond what was thought possible and sheds light on molecular strategies for survival in extreme heat.

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Now online! Chloroplasts balance energy production and stress resilience via a cold-induced signaling pathway dlvr.it/TVdxxT

Chloroplasts balance energy production and stress resilience via a cold-induced signaling pathway

Cold-stress signals are transmitted to chloroplasts and subsequently trigger cold responses through an RAF-like bi-kinase module where cytoplasmic RAF3 and plasma membrane RAF6 translocate to...

cell.com
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Last chance to register and save! The early registration discount for #CPSsinglecellbiology2026 ends today. Join an exceptional speaker lineup in Munich for three days of science, networking & a little Christmas market magic. Register: hubs.li/Q04y16Gy0
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Now online! mRNA-encoding CD19-targeting T cell engager for refractory immune thrombocytopenia dlvr.it/TVdYLD

mRNA-encoding CD19-targeting T cell engager for refractory immune thrombocytopenia

An mRNA-lipid nanoparticle-encoded CD19×CD3 T cell engager depletes B cells with attenuated cytokine release in preclinical models. In three patients with treatment-refractory immune thrombocytopen...

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Now online! Oligodendrocytes in central nervous system health and disease dlvr.it/TVdRRp

Oligodendrocytes in central nervous system health and disease

Oligodendrocytes, predominantly known for their role in myelination, play a broader role in regulating the central nervous system, including feeding axons and reshaping neural circuits, with their...

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In the latest issue! Synthetic transcription factors designed by domain recombination enhance CAR T cell antitumor function dlvr.it/TVdDXq

Synthetic transcription factors designed by domain recombination enhance CAR T cell antitumor...

Recombining domains across an entire protein family, rather than relying on natural sequences shaped by evolution, generates synthetic “DESynR” transcription factors with enhanced function. DESynR...

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In the latest issue! Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution dlvr.it/TVd6PC

Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution

(Cell 188, 6953–6970.e1–e8; November 26, 2025)

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In the latest issue! Fifteen challenges for generative AI applications to cell biology dlvr.it/TVcjKB

Fifteen challenges for generative AI applications to cell biology

Drawing inspiration from Hilbert’s list of 23 mathematical problems that have focused the mathematical community’s attention for more than a century, we propose fifteen grand AI challenges to focus...

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In the latest issue! The sex and reproductive plasticity of intestinal muscles instruct gut size dlvr.it/TVcbhd

The sex and reproductive plasticity of intestinal muscles instruct gut size

Adult intestinal size plasticity is driven not only by epithelial stem cells but also by remodeling of the surrounding visceral musculature. Sex- and reproduction-dependent muscle remodeling controls...

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In the latest issue! Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer dlvr.it/TVcNc0

Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer

Spatial multi-omics reveals macrophage states that constrain adaptive immunity in immunosuppressed non-melanoma skin cancer.

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In the latest issue! Distinct cellular phenotypes of language and executive decline in amyotrophic lateral sclerosis dlvr.it/TVcGHT

Distinct cellular phenotypes of language and executive decline in amyotrophic lateral sclerosis

Beyond its motor dimension, ALS can also involve cognitive impairment, with affected domains varying across individuals. Rather than a single common disease process, this heterogeneity reflects...

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In the latest issue! Spatial atlas of the human brain vasculature reveals specialized cell ensembles dlvr.it/TVbs4G

Spatial atlas of the human brain vasculature reveals specialized cell ensembles

An integrative cell and spatial atlas defines the organizing logic of the adult human cerebrovasculature, providing a framework for studying how vascular cell states support brain function and shape...

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In the latest issue! Dietary arginine drives codon-dependent MHC class I translation and improves immunity in colon tumorigenesis and respiratory viral infection dlvr.it/TVblFl

Dietary arginine drives codon-dependent MHC class I translation and improves immunity in colon...

Arginine availability regulates arginyl tRNA levels and codon-dependent translation of MHC class I, tuning antigen presentation and shaping anti-viral and anti-tumor immunity.

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🌎 How does life shape Earth’s chemical cycles? From molecular mechanisms to environmental function, we’re looking for ideas exploring how core biochemical principles scale to shape biogeochemical cycles and Earth system processes. Can you bridge these scales? We want to hear!
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In the latest issue! Why machines don’t speak biology: Toward native biological language models dlvr.it/TVbWlD

Why machines don’t speak biology: Toward native biological language models

Advances in AI have shown promise in protein structural information, but in this perspective, the authors argue that biology’s true complexity—emergent, evolved, and irreducibly messy—demands more...

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In the latest issue! Advancing cancer detection and treatment using longitudinal routine clinical data dlvr.it/TVbPRQ

Advancing cancer detection and treatment using longitudinal routine clinical data

Liu et al. develop Oncoformer, a multimodal transformer that reads routine laboratory tests and chest X-rays already collected in everyday care. Across more than 3.6 million individuals, it detects...

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In the latest issue! Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4 dlvr.it/TVb0lL

Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4

Cryoelectron microscopy structures of human CNNM4 in distinct conformational states reveal how an unexpected dimer-of-asymmetric-dimers architecture mediates Mg2+/Na+ exchange and identify an...

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In the latest issue! The intrinsic cardiac nervous system is essential for cardiac function and survival dlvr.it/TVZv3v

The intrinsic cardiac nervous system is essential for cardiac function and survival

Two genetically distinct neuronal subtypes in the intrinsic cardiac nervous system are differentially required for baseline cardiac function and stress resilience to maintain cardiac stability and...

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