The Sarosiek Lab @HarvardChanSPH studies the regulation of #apoptosis in human development and diseases.
Boston, MA
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Congrats Monica, Judith and team! We were so glad to contribute to this work, which has wide-reaching implications for how we treat cancers. Looking forward to continuing the collaboration and overcoming this resistance.
Metastasis kills most cancer patients and grows from invisible seeds. How do these seeds escape from attack by immune cells? These seeds harness stress hormones!🤯
thanks to @nyscf @parkerici for their support. Today at @Nature nature.com/articles/s41586-0…
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➡️Join our next BCDI meeting for exciting discussions on immune-competent organoid brain tumor models from Xin Tang @BostonChildrens and immune suppression in ovarian tumorigenesis from @TanjinaKader @harvardmed! Monday Sept 8th at 3PM @ Harvard Med Quad. BostonCellDeath.org
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Herculean effort from @deadoc80 and team to COMPREHENSIVELY review how #caspases promote or suppress inflammatory signaling. Recent discoveries show that caspase signaling, and ultimately organismal responses, are nuanced and context-dependent. #apoptosis #inflammation
Here comes our latest @NatRevMCB review on the control of #inflammation by #apoptosis, #pyroptosis and #caspases! Kudos to @RuthSAnyc and @Mbv26 for the heavy lifting! Not possible w/o input from @CellDeathLab and Doug Green!! @FoxChaseCancer @HarvardChanSPH @StJude
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➡️Join our next BCDI meeting for exciting discussions on programmed cell removal from @mounicav07 @broadinstitute and NK-mediated targeting of tumor cells from @MichalSheffer @DanaFarber! Monday April 7th at 3PM on the Harvard Med Quad. BostonCellDeath.org
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➡️Join our next BCDI meeting for exciting discussions on Regulatory T Cell fate from Xudong Li @tufts and modulation of Gasdermin D function in pyroptosis from lab of Hongbo Luo @BostonChildrens! Monday March 3rd at 3PM on the Harvard Med Quad. BostonCellDeath.org
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➡️Join us today at 3PM for the Boston Cell Death Initiative Discussion on #pericyte survival and #ferroptosis in hematopoietic stem cells! Goldenson 122 on the Harvard Med Quad.
➡️Join our next BCDI meeting for not-to-be-missed discussions on pericyte cell survival for capillary integrity from @KeYuan_BCH and preventing #ferroptosis in hematopoietic stem cells from @bloodgenes lab. Monday Feb 3rd at 3PM on the Harvard Med Quad. BostonCellDeath.org
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➡️Join our next BCDI meeting for not-to-be-missed discussions on pericyte cell survival for capillary integrity from @KeYuan_BCH and preventing #ferroptosis in hematopoietic stem cells from @bloodgenes lab. Monday Feb 3rd at 3PM on the Harvard Med Quad. BostonCellDeath.org
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The changes induced by PFAS may not always directly trigger these forms of cell death, but sensitizing neural cells to various forms of cell death can make them more vulnerable to a wide range of concurrent or subsequent exposures.
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Thanks for sharing this article, Joe. The two genes reported to change in response to PFAS have been linked with neural cell death in the past. MANF can prevent apoptosis while TXNIP can promote apoptosis or highly pro-inflammatory pyroptosis.
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➡️Join our next BCDI meeting for not-to-be-missed discussions on harnessing GSDMD-mediated cell death in cancer immunotherapy from @WuLabHarvard and neutrophil-derived vesicles from Hongbo Lou's lab. Monday Jan 6th at 3PM on the Harvard Med Quad. BostonCellDeath.org
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➡️Join our next BCDI meeting for exciting discussions on mechanisms of immune suppression in breast cancer from @shimada_kenichi and modulation of epithelial cell death by Shigella from lab of @Cammie_Lesser. Monday Nov 4th at 3PM on the Harvard Med Quad. BostonCellDeath.org
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Thank you for co-hosting the JBL Symposium with us Henning! You did a fantastic job and the symposium attendees really benefited from your leadership. We’re already looking forward to next year!
Just wanted to again express my appreciation for
✅the honor to co-host the 27th JBL Symposium @HarvardChanSPH
✅the amazing keynote speakers @DemariaLab_WCM @DrRebeccaHowel1 @HugoAerts
✅the lively audience
✅a smashing poster session with 4⃣🔥prices ‼️
🙏🙏🙏
Looking forward to another vibrant Symposium in 2025☺️
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Great opportunity to conduct high-impact, translational cancer research in a fantastic laboratory!
The Letai Lab at Dana-Farber and Harvard Medical School is hiring a cancer cell biology post-doc. Check it out, and please circulate! careers.dana-farber.org/job/…
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➡The JBL Symposium is tomorrow (Friday) at 1PM at Harvard TH Chan School of Public Health. Join us for exciting talks and discussion on the latest innovations in radiation sciences! Info and registration: hsph.harvard.edu/jbl-center/…
➡️Join us October 11th at the JBL Symposium to hear from leaders in radiation oncology and AI in medicine including
@HugoAerts (@harvardmed)
@DrRebeccaHowel1 (@MDAndersonNews)
@DemariaLab_WCM (@WeillCornell) &
@HenningWillers (@MGHCancerCenter)!
Info: hsph.harvard.edu/jbl-center/…
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The JBL Symposium is next Friday, October 11th - join us to learn about the latest innovations in radiation sciences from world-renowned experts! Deadline to submit an abstract for our poster session (with prizes) is Friday, October 4th, at 5PM. info: hsph.harvard.edu/jbl-center/…
➡️Join us October 11th at the JBL Symposium to hear from leaders in radiation oncology and AI in medicine including
@HugoAerts (@harvardmed)
@DrRebeccaHowel1 (@MDAndersonNews)
@DemariaLab_WCM (@WeillCornell) &
@HenningWillers (@MGHCancerCenter)!
Info: hsph.harvard.edu/jbl-center/…
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Join us on Monday @harvardmed at 3PM for two fantastic discussions focusing on cell death in radiation therapy and breast cancer metastasis!
➡️Join our next BCDI meeting for exciting discussions on targeting cell death for radiation therapy (@HenningWillers from @MGHCancerCenter) and breast cancer metastasis (lab of @JudithAgudo1 from @DanaFarber)! Monday Oct 7th at 3PM on the Harvard Med Quad. BostonCellDeath.org
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➡️Join our next BCDI meeting for exciting discussions on targeting cell death for radiation therapy (@HenningWillers from @MGHCancerCenter) and breast cancer metastasis (lab of @JudithAgudo1 from @DanaFarber)! Monday Oct 7th at 3PM on the Harvard Med Quad. BostonCellDeath.org
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➡️Join us October 11th at the JBL Symposium to hear from leaders in radiation oncology and AI in medicine including
@HugoAerts (@harvardmed)
@DrRebeccaHowel1 (@MDAndersonNews)
@DemariaLab_WCM (@WeillCornell) &
@HenningWillers (@MGHCancerCenter)!
Info: hsph.harvard.edu/jbl-center/…
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Reginald McNulty will be presenting at the Cell Death Initiative meeting on Monday on the HMS Quad - join us!
➡️Join us at the next BCDI meeting on Monday Sept 9th at 3PM on the Harvard Med Quad (Goldenson 122) for an exciting discussion with Reginald McNulty from @UCIrvine on using novel approaches to target the NLRP3 inflammasome. More info: BostonCellDeath.org
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