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New variable loop circular catheter waveform, Sequence 2, reduces PFA time 20.6s→3.8s and shows to be safe and effective in a preclinical model #Epeeps @True_EP @JonHsuMD @rahul3000 @JasperZouMD @JorgeERomero.MD @luigidibiasemd ahajrnls.org/46KjS1V
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The key glycolytic regulator PFKFB2 is lost with HFpEF, and its loss promotes repolarization prolongation, Ca2+ mishandling, and arrhythmogenesis #Epeeps @stavrosstavrak1 @ChiFungLeePhD @harold_kylene @Ken_Humphries ahajrnls.org/46KcweV
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New swine model combines ECMO + Impella to sustain VF without ischemia, enabling high fidelity heart mapping for arrhythmia research #Epeeps @attabehfar @f_delcarpio @nicktanCV @RC_Ward @EzzeddineMD @ikramhaqmd @DrDeese99 ahajrnls.org/4iJmF2K
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This pooled analysis showed high agreement and predictive ability of 6-month effectiveness endpoint with 12-month endpoint for AF ablation trials @drjasonandrade #Epeeps ahajrnls.org/4yJcTCc
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A high durable isolation rate of the pulmonary veins or roof/posterior wall block may be achieved provided a sufficient PFA application number is performed #Epeeps @SergeBoveda @gergoare @POllitrault @egandj @BeneytoDr ahajrnls.org/4AkOd4F
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After PFA, SCL incidence was similar across 4 strategies, but lesion burden differed—suggesting binary assessment may miss key differences #PFA #AtrialFibrillation #CardiacEP #MRI @TakaseTetsuro #StrokePrevention #Epeeps ahajrnls.org/4hdLZLO
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Pulsed field PVI left skin sympathetic nerve activity unchanged through 12 months, despite dose-dependent myocardial injury #EPeeps #AFib @ChinYuLin4 @lochieh19798 ahajrnls.org/3VzRehu
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In adults with D-TGA after atrial switch, catheter ablation is effective—but who is most likely to recur? Long-term data reveal predictors to guide follow-up @RaulmorenoMD @alvarez_cardio @Peinado1 #Epeeps ahajrnls.org/4xtsuVC
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In 6 RCTs (7,004 patients), LAAC lowered nonprocedural major bleeding but increased ischemic stroke vs OAC, with similar mortality @VijAviral
@adiaorta #Epeeps ahajrnls.org/45HafAH
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PFA often fails to transmurally block the mitral isthmus or denervate the Vein of Marshall. VOM ethanol infusion remains useful #EPeeps #AFib @patelapoor @NileshMathuria ahajrnls.org/4xQCUz2
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This article walks you step-by-step on how to design a pulsed field ablation catheter @JonPicciniSr @DanFriedmanMD @CRB_EP @atulverma_md #Epeeps ahajrnls.org/46hM7Vi
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CircEP retweeted
📢 #Stroke Bridge Seminar: Microvascular Dysfunction and Blood–Brain Barrier Breakdown in Stroke
🗓️ Thursday, August 27, 2026, 1:00–2:00 PDT | 20:00–21:00 UTC
🌟 Speakers: Yao Yao & @AndyShih_Lab
🌟 Hosted by @Chenhsbbb
📎 Register: ahajrnls.org/4cbX1iQ
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Isochronal CV better standardized VT substrate assessment in repaired TOF, predicting inducible MMVT with high NPV before TPVR #EPeeps
ahajrnls.org/3RD06lf
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A slow-conducing septal corridor prone to functional block explains the high prevalence of atrial flutter after atrial switch repair @EPBordeaux @KarimBenali42 @ArnaudMarine5 #Epeeps ahajrnls.org/3TwNfl0
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3D mapping of the human inferior pyramidal space reveals distinct autonomic pathways to the AV node and predominant posterior distribution of ganglia @OluAjijola #Epeeps ahajrnls.org/4yQrJYC
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Meta-analysis of 114,592 participants: AF risk increased only with high-dose EPA+DHA (>1500 mg/day) in high-CVD-risk populations
#Epeeps @CMAlbertEP @BudoffMD @MidAmericaHeart @frankq1368 @Azooz_Asbeutah @scholey @dvauzour ahajrnls.org/4fwuhDL
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In non-paroxysmal AF patients with enlarged LA, LAA ligation plus PVI may lead to improved freedom from AF #Epeeps @badhwarnitish @luigidibiasemd @drsuneet @cellisvandyep @OKhaliqueMD ahajrnls.org/45t1KZJ
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We discovered novel magnetocardiography parameters associated with subsequent appropriate ICD therapies, using a portable, unshielded, room-temperature MCG device #Epeeps @g_andre_ng ahajrnls.org/3Tlz9mo
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PFA induced coughing with focal dual-energy CF-sensing catheter without general anesthesia frequently necessitated a switch to RF at the posterior LA @EPBordeaux @KarimBenali42 @ArnaudMarine5 #Epeeps ahajrnls.org/4pTrGaB
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In swine, PFA near the sinus node and His bundle caused distance-dependent conduction injury #Epeeps @iwanari65284818 @TAMA07120380
ahajrnls.org/4vOGRmG
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