General Pathologist at Clinical Labs of Hawaii / Interest in BST & H&N

Straub Hosp, Honolulu, HI, USA
🧩 Kidney riddle Rare, certainly, but what a special morphology! A little question for the stain nerds: which stain would you try? #DxMindMap #KidneyPath #GUPath #PathTwitter @JHUpath @MGBpathology
3
29
84
4,130
Dan Graham retweeted
Nephrogenic Adenoma B E A U T I F U L 🥹 #GUpath #PathTwitter #PathX #pathology
2
20
43
1,857
PAX8 positivity in lower urinary tract urothelial carcinoma (including different clones)! Seen in pTa & invasive alike. Not just a peculiarity of upper tract urothelial Ca. Important #IHCPath fact to be aware of imo #GUPath #PathTwitter
#GUpath TURBT, prior high grade pTa PUC yes there is some lovely PAX8 positive flat pattern nephrogenic adenoma, but you'll also notice background pTa PUC is ALSO PAX8 positive! (NA was p63 neg; PUC was p63 pos) ⏬cont'd⏬
6
23
2,304
5cm breast mass in male patient. #PathX #PathTwitter
20
31
100
7,546
Dan Graham retweeted
This slide took “Chinese letters” literally First differential: Fibrous dysplasia 😂😎
1
3
8
857
85 man lung mass. Large IHC panel negative. Dx/ddx? #PathTwitter #PathX #ThoracicPath
16
6
32
2,885
50s M perineal mass. Dx? #DermPath #PathX #PathTwitter
12
17
49
3,672
60s M. Fungating arm mass. Sox10. Thoughts? #PathX #PathTwitter
4
6
22
1,561
60s F w/ hyperparathyroidism. parathyroid nodule. Dx? #EndocrinePath #HeadandNeckPath #PathX #PathTwitter
3
10
33
1,698
Thanks!
Replying to @DanGrahamMD
great Q! No minimum quant per say I report any %, as long as it is def chorio (syncytios+admixed cytotrophs; often assoc w/hemm). fortunately, per this paper limited chorio (<5%) likely not prognostic anyhow, but for completeness and to correlate with serum HCG I report any
1
7
1,063
60s F 5cm hypoechoic thyroid nodule. Dx? #HeadandNeckPath #EndocrinePath #PathX #PathTwitter
8
9
40
2,554
This is as good an example of Crooke hyaline change as you'll ever see, from a patient with Cushing's disease. Note the concentric rings on CAM 5.2. #pathology #neuropath #PathTwitter
2
24
98
3,709
Dan Graham retweeted
60s F with a cystic urachal lesion. Diagnosis? #PathTwitter @MGBpathology @MGHPathology
9
35
95
6,192
25 F scaphoid mass #PathX #PathTwitter
5
6
26
1,999
USP6 rearr. ABC!
2
219
4cm renal mass. To eat is human; to digest, divine.
3
11
58
3,104
The S100 makes me swoon every time. #PathX #PathTwitter #ENTpath #HeadandNeckPath
3
13
42
3,257
CD45+++, CD56+, CD4 patchy, CD43 patchy CD123, MPO, CD34, CD117, PAX5, CD20, CD3, CD138 k/l, TdT, CK, SOX10, MelanA negative. Thoughts? #HemePath #PathX #PathTwitter
70s M forearm nodule. Dx/workup? #PathX #PathTwitter
11
6
35
4,605