ALT DecodeME graphic. In the centre it says 'Thank you' in white cursive writing and beneath it 'from DecodeME'.

ALT DecodeME graphic. In the centre it says 'Your data and consent. If you took part in DecodeME, your data will continue to be held securely by the University of Edinburgh. Any consents you gave, for wider use or recontact, remain valid'. Beneath this in a speech bubble it says 'To update your details or consent, please email decodeme.ed.ac.uk'.

ALT DecodeME 'New Blog Post'. Titled: 'What's next for DecodeME?'. 'We shared our initial DNA results over the past few weeks to a wonderful response and widespread media coverage. Now, we are moving into the next phase of the study and have some updates to share.' There is an image of a scientist wearing goggles and pointing to a blackboard with a DNA helix.

ALT DecodeME post titled 'Support future ME/CFS research'. There is a picture of two hands and in between it is a green heart that says 'donate'. At the bottom of the graphic it says 'Donations will be used towards research projects such as the Genetics Centre of Excellence and Sequence ME and Long Covid.

ALT DecodeME 'The Results'. Post reads: 'Our Genetic Results webinar video and transcript are now available!'. Beneath this is an image of a clapperboard and an image of a transcript.

ALT New website! DecodeME's website has moved to the University of Edinburgh's site. Find the link in our bio.

ALT Image of Claire from DecodeME's PPI. Claire has fair skin, brown hair and is grinning. She is quoted saying "For DecodeME to show evidence validating ME as a physiological disease is enormously satisfying. My sense of pride and achievement at being part of this groundbreaking study is immeasurable. This solid scientific data from DecodeME brings new hope. I look forward to seeing where these discoveries lead for people with ME, and their families and carers."

ALT Photo of Tabby, a DecodeME participant, next to the quote: "Knowing that my DNA was a part of this study gives me a real sense of being part of something that is both exciting and could be the start of real change. Ever since my diagnosis I have been reading every bit of research I could find to try to understand this condition, and when I saw the opportunity to contribute to this study, I had to take it!'

ALT Screenshot of BBC Radio 5. Beneath this it says BBC Radio 5 Live, 7th August.

ALT Screenshot of The Guardian article by Ian Sample, 6th of August with headline 'Scientists find link between genes and ME/chronic fatigue syndrome'. Screenshot of The Times article by David Leask, 7th of August with the headline 'Lack of ME research because of 'medical misogyny', says top scientist', please note that this article is behind a paywall.

ALT Screenshot of Science article by Catherine Offord, 6th of August with headline 'Possible genetic clues to ME/ chronic fatigue syndrome identified in massive study'. Screenshot of New Scientist article by Michael Marshall 6th of August with headline 'Key genetic differences found in people with chronic fatigue syndrome'. Please note that this article is behind a paywall.

ALT News coverage. We have been blown away by the public interest in DecodeME's initial DNA findings. Please swipe to check out some of our press coverage. Links to full segments, interviews and articles will be in our bio.

ALT Screenshot of Prof Chris Ponting and DecodeME participant. Beneath this it says 'Channel 4 News at 7pm, 6th August'.

ALT Screenshot of BBC news reporter and Prof Chris Ponting. Beneath this it says BBC Scotland News at 7pm, 6th August.

ALT Screenshot of BBC Radio 4 Today. Beneath this it says BBC Radio 4 Today Program, 7th August.

ALT Photo of Sian Leary, from DecodeME patient and public involvement, next to the quote: "Having been on the Patient and Public Involvement Steering Group for the past 5 years, I want to celebrate this moment, but also to acknowledge the intense suffering pwME continue to endure. This study gives each of us validation that too often has been missing from healthcare professionals and close ones. We are a significant step closer to identifying the causes of ME, and to finding treatments."

ALT Photo of Andy Devereux-Cooke, PPI member and Co-Investigator, next to his quote: "DecodeME shows the incredible level of support that the ME/CFS community can give to research that involves them on a deep and meaningful level. Without the community, we could not have achieved all that we have"

ALT Genetic results webinar. Join us on Zoom or Facebook, Thursday 14th August 2025, 15:30-16:30 BST. Photos of the DecodeME management team.

ALT Photo of Sonya Chowdhury, next to the quote "These results are groundbreaking. With DecodeME, we have gone from knowing next to nothing about the causes of ME/CFS, to giving researchers clear targets. This brings ME/CFS in line with other long-term diseases which have genetic components."

ALT Image of Chris Ponting, next to the quote "This is a wakeup call. These extraordinary results speak the language of people with ME/CFS, often recounting people's ME/CFS symptoms. DecodeME is now calling on researchers worldwide to join us in accelerating ME/CFS research"

ALT Image of a website page with the text 'Frequently asked questions, DecodeME genetic results'

ALT Genetics Results Webinar. Join us on Zoom or Facebook. Thursday 14th August 2025. 3:30-4:30pm BST. Photos of Sonya, Chris and Andy from the DecodeME management team.

ALT Thank you to the thousands of people with Severe ME who have taken the time and energy to participate in DecodeME #SevereMEDay

ALT X marks the spot where ME/CFS biology can be discovered. The science behind the findings blog post.

ALT Graphic 1 of 4. DecodeME: The Results graphic. The slide says: ‘The signals discovered are involved in the immune and nervous systems, indicating immunological and neurological causes to this poorly understood disease’.

ALT Graphic 2 of 4. DecodeME: The Results graphic. The slide says: ‘At least two of the signals relate to the body’s response to infection’. Beneath this is an image of green germs.

ALT Graphic 3 of 4. DecodeME: The Results graphic. The slide says: ‘Other signals point to the nervous system, one of which researchers previously found in people experiencing chronic pain, reinforcing neurological contributions to ME/CFS’. Beneath this is an image of a person curled up in bed feeling ill.

ALT Graphic 4 of 4. DecodeME: The Results graphic. The slide says ‘All of these signals align with how people with ME/CFS describe their illness’.

ALT Graphic 1 of 4. DecodeME: The Results graphic. At the top in bold lettering, it says ‘Main Findings’. Beneath this it says ‘Your genes contribute to your chances of developing ME/CFS. Other key findings are on the following slides.

ALT Graphic 2 of 4. DecodeME: The Results graphic. The slide says ‘People with an ME/CFS diagnosis have significant genetic differences in their DNA compared to the general population’. Beneath this is an image of a DNA helix and a magnifying glass.

ALT Graphic 3 of 4. DecodeME: The Results graphic. The slide says ‘These lie in many places across the genome, and do not impact just one gene’. Beneath this is an image of a DNA helix and graphs.

ALT Graphic 4 of 4. DecodeME: The Results graphic. The slide says ‘Eight genetic signals have been identified. As DNA doesn’t change with ME/CFS onset, these findings reflect causes rather than effects of ME/CFS’. Beneath this is a blue magnifying glass with a DNA helix.

ALT DecodeME: The Results announcement post. The graphic has a blue background with a DNA helix. In the centre of the graphic it says ‘We have released our initial DNA results! We have discovered that your genes contribute to your chances of developing ME/CFS.’ At the bottom left of the graphic is an image of a research paper.

ALT Dark blue background with image of DNA helix. At the top of the DecodeME ‘the results’ logo. Two spotlights shine on a speech bubble that says ‘Initial DNA results’. To the right of this is an image of a research paper. At the bottom of the graphic it says ‘Wednesday 7pm BST’.

ALT Post reads: 'This week, the project team reached a significant milestone: we are into the final analysis stage which tests millions of DNA variants for their association to ME/CFS. Completion of the write-up and announcement of the results will follow as soon as possible. We are on target to deliver the results before the completion of the study in August and appreciate your continued patience and support. - DecodeME Team'

ALT At the top left hand corner is the DecodeME logo. Beneath this is an image of Claire. She has brown hair, fair skin and grins. Beneath this it says 'Claire Tripp, DecodeME PPI'. To the right of the picture "Being part of DecodeME’s PPI Steering Group has given me the chance to turn my daughter’s life-altering illness into something purposeful. When patients and carers are involved, research becomes not just more accessible - but more powerful. Beneath this: 'proudly supporting World ME Day'.

ALT DecodeME graphic. At the top left hand corner of the graphic is the DecodeME logo. Beneath this is an image of Sian. She has blonde hair, fair skin, wears glasses and grins. Beneath this image it says 'Sian Leary, DecodeME PPI'. To the right of the picture is a quote from Sian: "This World ME Day, I reflect with pride on the Patient and Public Involvement (PPI) at the core of DecodeME. This is research done differently - because we deserve better.' Beneath this: 'proudly supporting World ME Day'

ALT Below is a graphic for World ME Day. At the top right hand corner is the DecodeME logo. At the centre of the image is a quote from Professor Chris Ponting: "DecodeME is not just the world's largest study of the genetic causes of ME, but it was the first to place people with experience of ME at its heart. A total of 27,000 people with ME took part. At the bottom centre of the image in white it says 'proudly supporting World ME Day'.

ALT Graphic with dark blue background. At the top left hand corner is the DecodeME logo. Beneath this is a screenshot from the article, with the front cover a picture of someone beneath white bedding with their face and arm peeking out, and beneath this is the headline ‘Long Covid in its worst form’ and the subheading ‘Chronic fatigue syndrome affects millions of people and has been known for a long time. But patients were psychologized, stigmatized and treated incorrectly. It was only Long Covid that brought about a rethink. By Theres Lüthi, 08.01.2025’. Next to the screenshot of the article is a quote saying "What the research field now needs most urgently, says Ponting, is a robust scientific foundation... DecodeME, the largest ME/CFS study to date, is now taking a step in this direction in Great Britain”.

ALT Graphic with dark blue background. At the top right is a green DNA helix. At the top centre of the graphic is the DecodeME logo and beneath it says ‘would like to wish you a’ in light beige writing, and beneath this is a green circle that says ‘Happy New Year’ in white lettering in it. At the bottom of the graphic in white lettering it says ’Thank you for supporting the study, we couldn’t do it without you!’

ALT Graphic with a light cream background. At the top left hand corner are green, silver and black snowflakes. At the top right hand corner is a green DNA helix. At the top centre of the graphic it says 'Have a wonderful Festive Season! DecodeME is' in navy lettering and beneath it in a green circle 'Closed for Holidays' in black writing. At the bottom centre of the graphic it says 'from 20th Dec to 6th Jan'. At the bottom right is the DecodeME logo and at the bottom left is a green DNA helix.

ALT In the centre in a green circle it says ‘Thank you!’ In black lettering. At the bottom of the graphic it says ‘for everything we’ve achieved together in 2024’ in white lettering. At the top left of the graphic is the UKbiocentre and Thermofisher logo, beneath this it says ‘All of your DNA samples, over 18,000 of them, have now been processed and the genetic information received by the team.’ Next to this is a picture of a questionnaire, and beneath it says ‘Over 15,000 participants completed and returned the 2nd questionnaire.’ Next to this is an image of a black magnifying glass and a graph and underneath it says ‘We cleaned and prepared the sample data for analysis.’ Underneath this is an image of a green double helix and beneath this it says ‘We opened data access to other researchers.’ To the centre left of the graphic is a magnifying glass with a graph in it and beneath it says ‘We are deep into analysing the DNA data and comparing it to healthy controls'

ALT Graphic with yellowy beige background. At the top left there is the DecodeME logo, at the top right are dark blue and green baubles. At the top centre it says ‘Supporting someone with ME’. Beneath this it says ‘Remember to check in on your friend/ family member with ME this festive season and see what would be most helpful and comforting for them.’ Underneath this it lists suggestions to do this, including: Go shopping, call or text them to let them know you’re here for them, cook them a warming meal, keep including them in your plans even if they have to decline most of the time and sit with them quietly.

ALT Prof Chris Ponting in conversation with Jennie Jacques. Watch on Jennie's YouTube channel 'The Monster in ME'

ALT Dark blue graphic with DecodeME logo. Image of Chris looking into camera and half smiling. Beneath him is a small green banner that says "SevereMEDay". Next to him is a quote saying "Everyone with ME deserves better care and more research funding. Yet the terrible suffering of those with severe symptoms reminds us constantly of the importance of accelerating research." - Professor Chris Ponting, DecodeME Investigator.

ALT Image of tv screen with Action For ME CEO, Sonya Chowdhury smiling. In the left hand corner of tv screen is the BBC News Scotland logo. Beneath the TV is an image of a TV remote and writing that says 'BBC News Scotland Monday 29th July at 9pm'

ALT Image of Radio and on the screen it says 'BBC Drivetime Radio Scotland'. Beneath it is an image of Sonya smiling wearing a pink top. Next to her it says: Tune into BBC Radio Scotland Drivetime around 4:45pm today to hear Action For ME CEO, Sonya Chowdhury, talk about ME.'

ALT Image of Prof Chris Ponting looking into the camera. Next to him is his quote: "Funding per person, per year for people with ME is about £2-3, which is almost nothing for a country that is spending £70-80 a year per person on research and development." - Prof Chris Ponting, Investigator, DecodeME. Beneath the quote is the logo for BBC Radio Scotland and DecodeME.

ALT Screen grab of ME/CFS Researcher Toolkit article. Please click the link in the description to read the full article.

ALT BACME Presentation May 2024. Claire Dransfield - Research Manager, Action For ME. Prof Chris Ponting - Principal Investigator, DecodeME.

ALT DecodeME graphic with lilac background and dna helix. Top left corner is DecodeME logo. Top left corner is a hanging sign saying 'data access applications for researchers is now open!'. In the centre of the graphic is a green rectangular box with a quote inside, reading: "there has been much speculation about the role of iciHHV-6 in ME. This will be the largest study to address this question and should provide definitive answers." - Professor Ruth Jarrett. University of Glasgow logo.

ALT DecodeME and Precision Life graphic. At the top of the graphic are DecodeME and Precision Life logos. Beneath it says 'proudly support World ME Day 2024' with a green DNA helix on either side. Beneath it says: 'Thanks to the amazing 86% of DecodeME participants who consented to their data being shared with other researchers. Projects like this with PrecisionLife using DecodeME data can help accelerate research into new diagnostic and treatment options for those living with ME/CFS.'

ALT DecodeME Graphic. In the centre is a bubble with a green outline, inside the bubble is the DecodeME logo, and beneath it says 'Public Patient Involvement Group (PPI). At the top left corner of the graphic is an image of Andy smiling, to the right top corner is Sonya, smiles broadly, to the bottom left hand corner is Sian, she wears glasses and smiles, and to the bottom right is Claire who smiles broadly and has brown hair. At the bottom of the graphic is 'proudly supporting World ME Day'