DermatologyAdvisor.com offers dermatology specialists and other health care professionals a comprehensive knowledge base of practical information and resources
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Women with androgenetic #alopecia who received spironolactone had greater improvement in Sinclair grades from baseline to month 24 than those treated with bicalutamide.
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The mean change in Teoxane Midface Volume Deficit Scale scores from baseline to 8 weeks was -1.3 with RHA4 and -1.3 with an approved active comparator.
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Significant differences in neutrophil-to-monocyte ratio and neutrophil-to-lymphocyte ratios were noted in some groups with #rosacea.
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Among children with moderate to severe #AtopicDermatitis, 62% of boys and 48% of girls were below the 50th percentile for height, whereas 50% and 51%, respectively, were above the 50th percentile for weight.
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Women with severe #acne vulgaris had significantly higher levels of testosterone, dihydrotestosterone, and luteinizing hormone, as well as significantly lower levels of estradiol when compared with a control group without acne vulgaris.
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Among patients with hidradenitis suppurativa-related pain, oxycodone was the opioid most frequently prescribed in the emergency department whereas hydrocodone was most frequently prescribed in ambulatory settings.
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The combination of laser and intralesional #triamcinolone for the treatment of pathological scars was associated with significant improvements in Vancouver Scar Scale and modified-Vancouver Scar Scale scores.
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The AI tools moving fastest in dermatology are often the least rigorously validated, while clinical tools are advancing more slowly due to practical concerns about implementation.
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Subgroup analyses on the use of oral probiotic supplementation for improving skin outcomes revealed that a duration of 8 weeks and longer suggested greater benefits than supplementation for less than 8 weeks, though additional research is needed.
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Rates of response to treatment for plaque #psoriasis was 70.1% with biologic therapies, 45.8% with methotrexate, and 54.7% with phototherapy.
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In patients with #alopecia areata at 24 weeks of treatment with oral Janus kinase inhibitors, the odds of achieving a Severity of Alopecia Tool score of 10 and less were 5.69 times higher than with placebo, which increased to 9.40 times higher by week 36.
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Following 16 weeks of treatment with low-dose micronized #isotretinoin, patients with severe recalcitrant nodular acne achieved a 84.41% reduction in Investigator’s Global Assessment scores.
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Adherence to 4 healthy lifestyle behaviors was associated with a lower incidence of adult-onset #AtopicDermatitis when compared with those who adhered to 0 or 1 behavior.
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In the last decades, there have been strides to include women in clinical trials — after they were excluded until the 1990s.
Why were women historically excluded from clinical trials and what still needs to be done to create more equitable trials?
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Top benefits of telemedicine in the management of systemic therapies for #psoriasis and #AtopicDermatitis include time and cost savings for patients, whereas providing good service and valuable contributions to chronic care are top benefits for providers.
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Among melanocytic lesions with peripheral globules at baseline, 46.9% of lesions had complete globule resolution at follow-up, researchers concluded in @JAADjournals.
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At 2 years of treatment, 96.6% of patients with moderate to severe #AtopicDermatitis reported meaningful treatment benefit, but 74.9% reported improvement in #pruritus relief, which is the highest rated treatment priority.
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In the full-analysis population, 88.27% of those who received the lidocaine-premixed hyaluronic acid gel for nasolabial fold correction had improvements at 6 months compared with 85.19% of those who received the active control.
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From @BrJDermatol: Treatment with the highest dose of #delgocitinib cream, 20 mg/g, was associated with a mean change in #Eczema Area and Severity Index scores of -7.6 at 8 weeks compared with -1.9 with cream vehicle.
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#Cidofovir cream and imiquimod 5% are associated with the lowest risks for adverse events among adults with external anogenital warts.
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