Researcher/Lecturer@UZH_ch | Neurophotonics, functional neuroimaging, integrative human physiology, biophysics, signal processing, physics, philosophy and more
There is a significant lipid depletion (ether lipids, plasmalogens & cholesteryl esters) at baseline & after exercise in ME/CFS.
(Christopoulos et al., 2026, ovid.com/jnls/acsm-msse/full…).
This points to delayed aerobic recovery & persistent metabolic dysfunction underlying PEM
#MECFS
New finding: The spleen plays a key role in regulating platelet activity by clearing hyperactivated platelets from the bloodstream (Laun et al., 2026, science.org/doi/10.1126/scie…).
"... the spleen is a key modulator of thrombosis risk ..."
Overturning decades of scientific consensus, new research reveals that the brain actually develops as 2 separate, parallel organs (the forebrain/midbrain & the hindbrain) originating from distinct progenitor cells (Jokhai et al., 2026, nature.com/articles/s41593-0…)
The first human resting-state & task-based ultra-high-field fMRI study at 11.7 T!
(Obriot et al., 2026, direct.mit.edu/imag/article/…)
"This work paves the way for human #fMRI neuroscience studies at 11.7 T ..."
(11.7 T: roughly 234,000 times stronger than Earth's magnetic field)
Irradiation at 42.4 & 48.6 THz enhances the binding of the psychedelic ligands LSD & psilocin to 5-HT1A & 5-HT2A receptors (Zhang et al., 2026, pubs.acs.org/jpcbfk/article-…)
Basis for future "fundamental biophysical studies of physical-field regulation of receptor pharmacology"
Baby teeth from children with autism contain significantly higher levels of environmental toxins than those of healthy controls (Heilbrun et al., 2026), sciencedirect.com/science/ar…)
Especially high levels: benzyl benzoate (preservative in personal care products), plasticizers
The first double-blind, randomized, placebo-controlled, crossover study investigating a 120 mg dose of MDMA followed by a 60 mg booster (Humbert-Droz et al., 2026, nature.com/articles/s41398-0…)
(I was one of the study participants)
#psychedelics
A new study finds that toxins released from baby bottles can be detected in infants' teeth
(Heilbrun et al., 2026, sciencedirect.com/science/ar…):
- Phthalates
- UV filters & photoinitiators
- Polymer stabilizers
- Polymer intermediates
- Fragrance / flavoring agents
#health
Living near a dry cleaner is associated with an increased risk of developing Parkinson's disease (n =19 million people, Krzyzanowski et al., 2026, nature.com/articles/s41531-0…).
Dry cleaning facilities release neurotoxins into the air (perchloroethylene [PCE], trichloroethylene [TCE])
Cerebrospinal fluid drains to cervical lymph nodes via newly identified fenestrations in the arachnoid membrane surrounding olfactory bulbs (Hong et al., 2026; cell.com/cell/fulltext/S0092…)
Specific gut microbial pathways correlate directly with neurotransmitter levels (GABA & glutamate) in distinc brain regions (Johnstone & Cohen Kadosh, 2026; nature.com/articles/s41380-0…)
Bifidobacterium & Lactobacillus drive GABA synthesis, confirming their key role as "psychobiotics"
Serotonin-driven platelet hyperactivation directly promotes extensive fibrin deposition in the microvasculature (Marotta et al., 2026: science.org/doi/10.1126/scii…)
This finding could be relevant to explain the formation of persistent fibrinaloid microclots. @resiapretorius
The choline/creatine (CHO/CR) ratio in the left anterior cingulate cortex (ACC) is elevated in ME/CFS
(Mueller et al., 2019: link.springer.com/article/10…)
- CHO/CR: linked to glial proliferation (neuroinflammation)
- ACC: Important for autonomic regulation
#MECFS#brain