Genetic Engineering & Biotechnology News@GENbio

Serving the biotech industry since 1981. EIC @johnsterling4; publisher @liebertpub Subscribe to GEN: ow.ly/XOjEe

 New Rochelle, NY
genengnews.com
Joined April 2009
32,091 Photos and videos
Unlock the secrets of bsAb purification! Join our free GEN webinar with Emily Gaither on a two-step polishing strategy for bispecific antibodies. Register now: hubs.li/Q04y9-Hw0 @thermofisher #Chromatography #DownstreamProcess #Bioprocessing
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Model-Free, Pure Component Analysis Could Help Biopharma Cut Costs Tunable laser near-infrared spectroscopy could help drug firms lower analysis costs and accelerate decision-making #NirrinTechnologies #biopharmaceuticals #spectroscopy hubs.li/Q04ykBPg0

Model-Free, Pure Component Analysis Could Help Biopharma Cut Costs

Tunable laser near-infrared spectroscopy could help drug firms lower analysis costs and accelerate decision-making.

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APOE4 Linked to Potentially Reversible Mechanisms of Brain Blood Vessel Damage in Alzheimer’s The team found mechanisms by which APOE4 changed pericytes and caused cholesterol to accumulate in astrocytes to promote #neurodegeneration @IcahnMountSinai #AD hubs.li/Q04ykycP0

APOE4 Linked to Potentially Reversible Mechanisms of Brain Blood Vessel Damage in Alzheimer’s

The team found mechanisms by which APOE4 changed pericytes and caused cholesterol to accumulate in astrocytes to promote neurodegeneration.

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Discover the future of ADCs! Join Cindy Cheng, PhD, as she reveals how dual-payload bioconjugates overcome resistance pathways. Register for the free GEN webinar sponsored by WuXi XDC: hubs.li/Q04xBnBq0 #Biopharma #ADC #Webinar
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As BPI comes to an end, so does our time with Editor in Chief @JohnSterling4. GEN is celebrating John’s many years of covering BPI and the remarkable career he has built along the way.
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ADCs, mAbs, CAR Ts: One Bioluminescent Platform Measures Them All The HiBiT Target Cell Killing platform, with off-the-shelf, mix-and-match components, measures four killing mechanisms for broad immunotherapy modality assessment. Sponsored by @promega hubs.li/Q04y8kdp0

ADCs, mAbs, CAR Ts: One Bioluminescent Platform Measures Them All

The HiBiT Target Cell Killing (TCK) platform, with off-the-shelf, mix-and-match components, measures four killing mechanisms for broad immunotherapy modality assessment.

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Tautomer-Predictor AI Tool Identifies Stable Molecules for Drug Discovery Researchers have released their method as an open-source tool that can rapidly analyze very large molecular libraries @nyuniversity #AI #drugdiscovery #tautomer hubs.ly/Q04yd0qx0

Tautomer-Predictor AI Tool Identifies Stable Molecules for Drug Discovery

Researchers have released their method as an open-source tool that can rapidly analyze very large molecular libraries.

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Mark Your Calendar! In this 9/30 GEN webinar, USP and Alphalyse present the work qualifying beta-lactoglobulin (LACB) as a cross-platform standard for LC-MS/MS HCP analysis. Register for this FREE webinar sponsored by USP: hubs.li/Q04w4G7N0 #Biopharmaceuticals #Proteins
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Top 10 Contract Development and Manufacturing Organizations 2026 @AlexWestchester analyzes the top CDMOs this year, as #biopharma is expected to increase their reliance on #CDMOs in coming years despite rising costs for their services #bioprocessing hubs.ly/Q04yc_Bn0

Top 10 Contract Development and Manufacturing Organizations 2026

A majority of biopharmas are expected to increase their reliance on CDMOs in coming years despite rising costs for their services.

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New eBook Available! This eBook introduces the latest trends in quantitative spatial biology and how IMC is accelerating their adoption and success. Download this FREE eBook sponsored by Standard Biotools: hubs.li/Q04wgYDq0 #Biomarkers #PrecisionMedicine #SpatialBiology
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Cell Senescence 'Barcodes' Identified with Raman Microscopy and Gene Expression Data Tracking down #senescentcells, which accumulate as we age, could help diagnose #agerelateddisorders and guide researchers working on new treatments @JianShuLab @MIT hubs.li/Q04y72Gs0

Cell Senescence 'Barcodes' Identified with Raman Microscopy and Gene Expression Data

Tracking down senescent cells, which accumulate as we age, could help diagnose age-related disorders and guide researchers working on new treatments.

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AI Drug Discovery Hits a New Bottleneck: Experimental Validation AI can now generate drug candidates faster than labs can test them, shifting pharma’s challenge from molecular design to experimental validation. Sponsored by #ProBio hubs.li/Q04y1SRg0

AI Drug Discovery Hits a New Bottleneck: Experimental Validation

AI can now generate drug candidates faster than labs can test them, shifting pharma’s challenge from molecular design to experimental validation.

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Targeted Lentiviral Delivery Without Vector Reengineering G-Link simplifies ex vivo T-cell engineering by using targeting, activation, and transduction, while enabling targeted T-cell delivery in vivo through postproduction mixing Sponsored by @VyriadMN hubs.li/Q04xXLm_0

Targeted Lentiviral Delivery Without Vector Reengineering

Rather than requiring genetic modification of the viral glycoprotein, G-Link uses a modular protein adaptor to blind native VSV-G tropism and redirect delivery after vector production.

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H5N1 Spreads Among Australian Wildlife as Flu Season Ramps Up Australia is closely monitoring the H5N1 influenza strain after detections in sea lions, seals, dolphins, and foxes @DuckSwabber @SVermund @GlobalVirusNews #influenza #mammals #epidemiology hubs.li/Q04y1PLL0

H5N1 Spreads Among Australian Wildlife as Flu Season Ramps Up

Australia is closely monitoring the H5N1 influenza strain after detections in sea lions, seals, dolphins, and foxes.

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Discover the future of microbial-derived biologics! Join GEN’s free webinar with Sam Zhang, PhD, on trends in late-stage scale-up and CDMO needs. Register: hubs.li/Q04xyX7j0 @WuXiBiologics #Biomanufacturing #Fermentation #Microbiology #Peptides
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StockWatch: Novo's 2030 Strategy Underwhelms Investors at Capital Markets Day A week after rebranding itself as “Novo,” @novonordisk has laid out a strategy for 2030 that underwhelmed investors, sending shares lower #GENEdge #diabetes #metabolicdisorders hubs.li/Q04y1MvK0

StockWatch: Novo's 2030 Strategy Underwhelms Investors at Capital Markets Day

A week after rebranding itself as “Novo,” Novo Nordisk has laid out a strategy for 2030 that underwhelmed investors, sending shares lower.

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Last chance—GEN's State of Biotech is tomorrow. Maraganore. Orkin. Google Cloud's Shweta Maniar. The Biotech Hangout hosts. And John Sterling's exit interview after four decades as GEN's Editor in Chief. Free registration: hubs.li/Q04x-T-z0 #biotech #stateofbiotech
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Mark Your Calendar! Is Targeted Protein Degradation the “Break” Neurology Needs? Register for this FREE October 1 webinar sponsored by @ArvinasInc: hubs.li/Q04vBpdp0 #Alzheimers #Parkinsons #GeneticVariants
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Two-Organ View of the Human Brain Emerges Discovery could open up new avenues for studying diseases that affect the brainstem, such as #spinalmuscularatrophy and amyotrophic lateral sclerosis @StanfordMed @Caltech @UCSF #ALS #braindevelopment hubs.li/Q04xYh800

Two-Organ View of the Human Brain Emerges

Discovery could open up new avenues for studying diseases that affect the brainstem, such as spinal muscular atrophy and amyotrophic lateral sclerosis.

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Lilly's GIP/GLP-1 Candidate Brenipatide Shows Early Clinical Promise in Substance, Psych Disorders @EliLillyandCo presented early positive clinical data for its GIP/GLP-1 receptor agonist candidate in #substanceuse, psychiatric, and #immunologicdisorders hubs.li/Q04xYsZD0

Lilly's GIP/GLP-1 Candidate Brenipatide Shows Early Clinical Promise in Substance, Psych Disorders

Eli Lilly has presented early positive clinical data supporting once-weekly dosing for its GIP/GLP-1 receptor agonist candidate brenipatide in substance use, psychiatric, and immunologic disorders—...

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