Low cortisol people feel MORE stressed. In this study, lower cortisol people reported: - higher perceived stress - more depressive symptoms - more physical complaints - but lower allostatic load
Most people get it wrong with cortisol. Lower cortisol is a bigger problem that raised cortisol, particularly with chronic stress. Or, alternatively, issues with lower HRV is what makes cortisol spikes problematic.

Sep 8, 2026 路 5:52 AM UTC

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Replying to @GutOptimized
Because its prolonged chronic stress
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Yep, I think this is a major driver.
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Replying to @GutOptimized
It is very documented in me cfs patients. It may contribute to pem.
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Replying to @GutOptimized
Adrenalin / noradrenaline
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