Roh Lab@HyunRohLab

Roh Lab at Indiana University School of Medicine

 Indianapolis
hyunrohlab.com
Joined June 2020
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In @elife: Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity doi.org/10.7554/eLife.97981.…
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Check out our new paper, with help from @SheetsLabIUSM and @HyunRohLab . We identify a key downstream node from the Ventromedial hypothalamus in adaptive thermogenesis that is crucial for energy balance. doi.org/10.1016/j.molmet.202…
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Be cautious when using Ucp1-Cre/CreERT in your studies! Uncoupling protein 1-driven Cre (Ucp1-Cre) is expressed in the epithel... sciencedirect.com/science/ar…
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We finally report our effective nucleus isolation method for single-nucleus RNA-seq: Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity biorxiv.org/content/10.1101/…

Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose...

Single nucleus RNA sequencing (snRNA-seq), an alternative to single cell RNA sequencing (scRNA-seq), encounters technical challenges in obtaining high-quality nuclei and RNA, persistently hindering...

biorxiv.org
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Chronic cAMP activation induces adipocyte browning through discordant ... sciencedirect.com/science/ar… The very first paper from @HyunRohLab I am proud of the collaboration among the lab members. We're such a great team!
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SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry nature.com/articles/s41586-0…
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Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes nature.com/articles/s41586-0…

Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes

Nature - A study examining DNA transfer from mitochondria to the nucleus using whole-genome sequences from 66,083 people shows that this is an ongoing dynamic process in normal cells with distinct...

nature.com
⁦@HyunRohLab⁩ lab lunch to celebrate Chan’s birthday.
I just donated to @Wikipedia. Support free knowledge! #iloveWikipedia donate.wikimedia.org/?utm_me…
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Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation cell.com/cell/fulltext/S0092…

Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene...

The developmental events following gamete fusion are guided by maternally provided mRNAs and proteins prior to zygotic genome activation. Samata et al. show that H4K16ac transmission from the...

cell.com
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nature.com/articles/s41586-0…
Flipping the switch on the body’s thermoregulatory system nature.com/articles/d41586-0…

Flipping the switch on the body’s thermoregulatory system

Nature - A population of preoptic neurons that help regulate body temperature.

nature.com
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