A collective of expert urologists, medical specialists, and experienced researchers working to change the way the world diagnoses and treats prostate disease
Imperial College, London
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🚨 NEW IN @EUplatinum! 🚨
The largest analysis of focal therapy by Imperial Prostate and UK colleagues, reporting 1⃣0⃣-year outcomes after focal HIFU and cryotherapy in 3⃣4⃣7⃣7⃣ men 🔥🧊
Led by @AJWLight @LondonProstate1 @TaimurShah
Read for free: europeanurology.com/article/…
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🚀 Save the date for the Imperial Prostate Masterclass 2027! #ipmasterclass27
Join leading experts from around the world for cutting-edge lectures and hands-on training sessions! 🌍🔬
📅 Friday 16 April - Saturday 17 April 2027
🎟️ Register your interest: imperialprostatemasterclass.…
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Imperial Prostate retweeted
Fantastic day @ictmc2026 to see novel #AVIDITY and #TRANSFORM trial designs presented by @QMUL collaborators
IP10-AVIDITY - efficient random disclosure controlled trial design
IP12-TRANSFORM - innovative data-led strategy to widen participation in PCa screening
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New milestone reached!
IP10-AVIDITY has now recruited over 50 patients.
Congratulations to @royalmarsdenNHS for recruiting the 50th patient 👏
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Imperial Prostate retweeted
Alot of great work and forward progress by our colleagues across the Pond at @IP_London @LondonProstate1
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🎉 Delighted to welcome Sunderland Royal Hospital (@mccrackenstuart, Fraser Barbour) & @FreemanHospital (@rajan_vpillay, James Leighton) to #IP16SCOPE, an international service evaluation on #ActiveSurveillance in #ProstateCancer!
📩Interested? Email us: ip16-scope@imperial.ac.uk
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🚨NEW PUBLICATION🚨
IB1-LASERCOMPLETE live in @BJUIjournal!
@TUF funded prospective feasibility study in bladder cancer:
👉 Can FCM help detrusor muscle detection in TURBT samples
📄 Read it free: doi.org/10.1111/bju.70395
Thank you to the funder, all co-authors and the patients!
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Great presentation of the #IB1LASERCOMPLETE results looking at #FCM for detrusor muscle detection in TURBT samples by @Archana_GK1 at #SGU2026 (St Gallen)
✅ 100% feasible to interpret FCM images
✅ High inter-observer agreement
🔍 Exploratory diagnostic performance unclear
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Imperial Prostate retweeted
📢 New publication in European Urology
We are pleased to highlight a new study published in European Urology, titled “Five-year Outcomes for Men after Negative Magnetic Resonance Imaging (MRI) or Negative Biopsy in the RAPID MRI-directed Prostate Cancer Diagnostic Pathway”.
👏 Congratulations to Chase Ng, Alexander Light, and Taimur Shah on this excellent contribution, together with all co-authors.
🔗 Read the full article here:
👉 buff.ly/vMzTvKo
#EuropeanUrology #Urology #UroOncology #Research #MedicalResearch #AcademicUrology
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Imperial Prostate retweeted
Wholeheartedly recommend applying!!
📣 Calling all aspiring academic urologists: we are hiring!
Applications open soon for the 2027 @NIHRresearch Academic Clinical Fellowship in urology.
Join our 🌍-leading #ProstateCancer research group led by @LondonProstate1 💫
imperial.ac.uk/medicine/stud…
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📣 Calling all aspiring academic urologists: we are hiring!
Applications open soon for the 2027 @NIHRresearch Academic Clinical Fellowship in urology.
Join our 🌍-leading #ProstateCancer research group led by @LondonProstate1 💫
imperial.ac.uk/medicine/stud…
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Imperial Prostate retweeted
Reasonable precis of some of my work
You omitted another relevant bit though
The TRANSFORM screening RCT (that I am Chief Investigator for) in which focal therapy is mandated in the screening arms (n=150-300K) (£60M from @ProstateUK & UK National Institute for Health Research
Fantastic news! Please correct me if I’m wrong or missing anything as I wish to have a good understanding of the RCTs in this space
IP4-CHRONOS-A
Focal HIFU/cryo vs surgery/RT
Closed after pilot failed its feasibility criterion
IP17-APOLLO
Focal therapy ± 3 months neoadjuvant apalutamide
Does not establish focal therapy vs radical therapy
CHRONOS-B
Focal therapy alone vs focal + short neoadjuvant hormonal manipulation
Closed pilot. Feasible, but again not FT vs standard definitive treatment
IP2-ATLANTA
In de novo mHSPC: SOC vs ablative prostate treatment vs radical local therapy, with MDT strategies
Fascinating, but this is cytoreduction in metastatic disease, not a test of focal therapy as definitive localized therapy
PART
Partial ablation vs radical treatment
The most important UK RCT, but Ahmed is not the chief investigator
For partial ablation, the current protocol can allow a repeat focal ablation before declaring failure.
So, is there an RCT he is running that compares FT to definitive treatment?
Very interested to learn more if so or be corrected if I’m off the mark.
Thanks in advance and for all of the hard work!
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Imperial Prostate retweeted
Deep respect to @LondonProstate1 Prof. Hashim Ahmed for his unwavering commitment to advancing prostate cancer care. Designing and executing RCTs comparing focal ablation to whole-gland radical treatment is notoriously difficult due to patient preferences and recruitment hurdles. Yet, he remains one of the few investigators in the world actually leading multiple prospective RCTs in this space allowing us to build the evidence base we all rely upon.
Clearly you did not read the manuscript and have minimal grasp of radiation biology. They used low dose SBRT, which did have improved QOL/reduced toxicity in select domains, but will not show superiority with those doses which are not standard today.
Most people who use that Rx give a 120% hotspot, but they did not even allow dose much over 38 Gy to hotspots!
PACE-B gave Rx of 40 Gy with hotspots over 44 Gy. This may not seem like a lot to you, but it is a big difference.
Hilarious this is coming from the biggest proponent of focal therapy who cant even run a single RCT to prove it helps patients.
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Imperial Prostate retweeted
Dear @LondonProstate1
Leadership often comes with scrutiny, and with unfair criticism. It is difficult to witness someone who has dedicated so much to advancing patient care, research, education, and innovation become the target of personal attacks and coordinated hostility.
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#IP10AVIDITY update after a strong July for recruitment
4⃣0⃣ patients recruited from 2 main sites and 2 PICs
New sites opening soon helping to answer PSMA PET clinical utility and cost-effectiveness questions
Thanks to all patients and all those involved
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Imperial Prostate retweeted
Hot off the press!
Our initial experience with the novel Intilume system (Agilis Robotics, Hong Kong) for Robotic en bloc resection of bladder tumor with 2 fully flexible robotic arms (3.2mm) !
European Urology article:
sciencedirect.com/science/ar…
Video: surgery.cuhk.edu.hk/Agilis-I…
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Imperial Prostate retweeted
Not surprising - lots of extra (potentially unnecessary) ADT use for tiny glowing spots only seen on PSMA
Need to tackle the utility question - IP10-AVIDITY RCT currently strong recruitment
@IP_London @_Sam_Morris_ @Connor_Urol
Receipt of prostate-specific membrane antigen positron emission tomography for #ProstateCancer staging was associated with higher initiation rates of androgen receptor pathway inhibitor therapy and increased use of systemic treatment. ja.ma/4bXVb4W
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Imperial Prostate retweeted
Results from a large UK registry study suggest that focal HIFU and cryotherapy provide durable cancer control with low prostate cancer mortality in select patients with nonmetastatic prostate cancer. #pcsm urologytimes.com/view/large-…
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RT @ezebecher: Congratulations to @AJWLight and colleagues on this outstanding @EUplatinum publication! Great to see these important findin…
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Imperial Prostate retweeted
📰 NEWS: A targeted and minimally invasive prostate cancer treatment called focal therapy, which destroys only the cancerous part of the prostate, is effective in delivering long term outcomes for patients, according to a study
Read more: oncologynewstoday.co.uk/new-…
@ImperialNHS
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#IP7 #PACIFIC has recruited its 2️⃣0️⃣0️⃣0️⃣th patient! Well done to all sites involved, and to Southend @MSEHospitals who recruited patient number 2000!
Not long to go!
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