Assistant prof at @StanfordMed. Interested in aneuploidy, mitotic kinases, cancer therapeutics, and drug development. Co-founder x2.

Check out our new study in @ScienceMagazine, where we take on a 100-year-old debate: what’s the role of aneuploidy in cancer? We discovered that genetically removing extra chromosomes blocks cancer growth - a phenomenon we call “aneuploidy addiction”. science.org/doi/10.1126/scie…
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Jason Sheltzer retweeted
wow so much drama about navier stokes. had no idea things could blow up so infinitely in such a finite time.
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Huda Zoghbi came to the US as a refugee from Lebanon. At Baylor, her lab discovered the cause of Rett syndrome. She recently founded Cajal Neuroscience to develop new drugs for Parkinson’s. If America wants to lead in STEM, we should let in more immigrants like Huda, not fewer.
Columbia University will award the 2026 Louisa Gross Horwitz Prize to Adrian Bird and Huda Zoghbi for their pioneering work on epigenetic regulation in the nervous system and its role in human neurological disease, particularly Rett syndrome. Read more: cuimc.columbia.edu/news/2026…
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Requiring biomedical PhD students to write a dissertation before graduation is outdated - I think that establishing a preprint/publication requirement in lieu of a dissertation is better for students and better for the scientific community.
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Objection: dissertations are a good venue for negative data and failed experiments. But in 2026, there are tons of venues for these sorts of results - preprints, supplemental materials, “micropublications”, etc.
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To me, a dissertation feels like a deadweight cost: the PhD student’s valuable time, the PI’s limited funding, and the PhD committee’s scarce attention, spent producing and editing an inaccessible document likely to be buried on the PI’s bookshelf. We can do better!
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At-home pregnancy tests were invented in 1967, but for years the FDA prevented them from being sold to consumers. Regulators believed that it was dangerous for people to be able to obtain this information directly - medical information had to come from a doctor, of course.
We’re updating Claude Fable 5’s biology safeguards to reduce false positives. In our testing, this update reduced biology-related fallbacks by about 85% across our product surfaces. Fable can now assist on a wider range of everyday health and educational questions. We believe the biggest positive impacts of AI will be in biology and medicine, and we’re committed to putting frontier intelligence safely into the hands of as many researchers as possible. Fable will continue to fallback to Opus 5 for requests we consider dual-use—including virology, toxicology, and molecular design—so it isn't yet usable for professional biology research and drug development. We're committed to closing that gap through trusted access pathways for frontier biology capabilities. anthropic.com/news/improving…
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Still too dangerous for people to find out:
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Still interviewing for these positions! Experience with mouse cancer models is preferred but not required.
My lab at @Stanford is looking to hire postdocs for multiple projects on cancer biology and therapeutics. Our recent work has uncovered some truly remarkable mechanisms for cytotoxic small molecules and we're looking to build on this research. If interested, see below:
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Jason Sheltzer retweeted
Diabetes researchers ejected from conference after criticizing White House. The editor of ADA journal Steve Kahn was nondisruptivedly handing out his recent editorial in ADA journal that criticized Trump NIH policies. Big mistake by @AmDiabetesAssn washingtonpost.com/health/20…
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imagine what we could accomplish if we decided that expanding the grant program that produced Google was a national priority.
NSF-supported graduate students created a tool in the early 1990s to map links between webpages, helping people navigate the growing internet. That prototype laid the groundwork for what would become one of the world's largest companies: Google. brnw.ch/21x34io 📸:CQIM
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Sounds great - we're recruiting right now!
Your research is amazing....when I sell my next company maybe I can do a sabbatical in your lab !
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Jason Sheltzer retweeted
Challenges in Drug Discovery: Biology— Paul Workman and Jason M. Sheltzer will address this topic in a special session at the AACR D3 Conference on Drug Discovery and Development (July 21-24; Boston). Learn more: brnw.ch/21x2wGk #AACRdrugdev26 @JSheltzer
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