In Atlanta at the @BAPSCharities Healthcare Professionals Conference, I spoke on "Precision Oncology 2026: 5 Things Every Physician Should Know" for clinicians from across medicine 🎤 Here are the highlights 🧵 @SylvesterCancer @GlopesMd @HemOncMiami @Latinamd @RamalingamMD

Sep 27, 2026 · 1:29 AM UTC

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🩺 Screening remains foundational. Multi-cancer early detection is promising: NHS-Galleri reduced stage IV diagnoses, though it missed its primary endpoint! FDA advisory board - evaluated positively. @wsj_com article by @GlopesMd : wsj.com/opinion/the-galleri-…
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🩸 Liquid biopsy is real-world practice, and it complements tissue. Blood can find drivers when tissue is limited, slow, or unsafe to get, and together they catch more than either one alone.
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⚠️ Novel therapies, novel toxicities: irAEs, CRS and ICANS with bispecifics, and ILD with ADCs. Early recognition and an early call to oncology matter.
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🤖 AI mirrors the maturity of the evidence and should augment judgment, not replace it, with dharma-based guardrails: truth, non-harm, discernment and service. @Larvol @OncLive
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🧪 Phase 1 trials are no longer a last resort. They increasingly give patients early access to targeted and novel therapies, and a timely referral can open doors.
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🍷 I ended with prevention. Our @ASCO 2025 study and recent publication @LancetRH_Americ found that the share of cancer deaths attributable to alcohol significantly went up in US adults 20 and older over 33 years, across breast, colorectal, liver, pancreatic, stomach, prostate and head and neck cancers. Prevention starts in primary care @GlopesMd @SylvesterCancer @CNN
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