For obvious reasons, I've become fascinated with retrotransposons. So we (Alex Whiteley and I) wrote an article now out in @NeuroCellPress on how we think retrotransposons influence brain function and health! sciencedirect.com/science/ar…
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we recently reported a previously unknown myelin pathology in a retrotransposon-driven neurodegenerative disease biorxiv.org/content/10.1101/…

Myelin pathology is a key feature of X-linked Dystonia Parkinsonism

X-linked Dystonia-Parkinsonism (XDP) is a progressive, adult-onset neurodegenerative movement disorder that predominantly affects males of Filipino descent[1][1]-[3][2]. The disease is caused by the...

biorxiv.org
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Replying to @pryprk @NeuroCellPress
Cool! We concentrated on LTRs for this article...so not SINE/LINE elements...but those are also super interesting, of course.

Oct 20, 2025 · 10:00 PM UTC

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