We are thrilled that our recent study lead by @BayerlFelix is out in @ImmunityCP today. We addressed the question how cDC1 dysfunction is regulated in tumors and to which extent this contributes to cancer immune evasion. It is Open Access!👇 cell.com/immunity/fulltext/S… A short 🧵:

Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of...

cDC1s are critical for effective anti-cancer immunity but often dysfunctional in tumors. Bayerl et al. reveal that PGE2 controls cDC1 function locally in tumors through the downregulation of IRF8,...

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Replying to @JBoettcherLab @ImmunityCP
Congratulations, Jan! Very interesting and important study! Very good start as a group leader! We are lucky to have your team in our Institute 😊

Jun 13, 2023 · 6:18 PM UTC
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