From whole animals down to single molecules @LJIresearch. Tweets by the members of the core + @zmikulski

La Jolla, San Diego
LJI Microscopy Core retweeted
I just wanted to add that our FSD* is open source, and you do not need to keep your hands on the steering wheel! *Fluorescence Self Driving
The self driving multi-scale microscope from @Daetwyler_St is out. It can image a whole zebrafish embryo longitudinally and follow a region of interest with high resolution. We use it to study immune-cancer cell interactions. nature.com/articles/s41592-0…
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LJI Microscopy Core retweeted
Measles outbreak erupts in one of Texas’ least vaccinated counties dlvr.it/THrtv4
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LJI Microscopy Core retweeted
1) Since there is a lot of confusion about the reduction of the overhead rate on NIH grants to 15% (see here: grants.nih.gov/grants/guide/…) I'll do a little tweetorial (or X-torial?) about it.
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LJI Microscopy Core retweeted
The National Institutes of Health plans to severely cut the percentage of its grant money that can be used for overhead costs rather than research. scim.ag/42LPG5S
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LJI Microscopy Core retweeted
This rate of validation suggests that antibodies should be considered non-specific until proven otherwise: 357 validated out of 1,124 tested. .
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Join us! In two days we will teach you how to analyze complex immunofluorescence multiplex data. It will take you weeks to months to learn this on your own!
📢Announcing a QuPath Workshop 📢 February 24-25, 2025, in San Diego, CA, at the La Jolla Institute for Immunology. This year’s event will be all about Multiplex Immunofluorescence Analysis. The workshop will be followed by an 🎉 Advanced QuPath User’s Meeting 🎉- Feb 26
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LJI Microscopy Core retweeted
Applications for our Quantitative Imaging From Acquisition: to Analysis 2025 course @QIatCSHL (Mar 24-Apr 8) are due on Jan 31! . Come immerse yourself in microscopy and image analysis with me, @TalleyJLambert, @florianjug, @BoSoxBioBeth & Hunter Elliott! Please RT! @cshlcourses
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LJI Microscopy Core retweeted
We're thrilled to showcase this mouse ileum image, submitted by Simon Goldstein, @LJIMicroCore, in our 2025 Calendar! 📸 Image Details: 15-channel imaging of a normal murine ileum spiral, acquired on the Orion Spatial Biology Platform. #SpatialBiology #MultiplexImaging
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LJI Microscopy Core retweeted
Hey PIs, do your trainees need to learn light microscopy and image analysis? Send them to us! Financial aid is available. meetings.cshl.edu/coursesint…
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📢Announcing a QuPath Workshop 📢 February 24-25, 2025, in San Diego, CA, at the La Jolla Institute for Immunology. This year’s event will be all about Multiplex Immunofluorescence Analysis. The workshop will be followed by an 🎉 Advanced QuPath User’s Meeting 🎉- Feb 26
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We will stream the sessions on Zoom, though we won't be able to provide the same level of help for remote attendees as for in-person attendees. (Virtual-only registration will be available soon). You can watch the 2023 edition here: piped.video/playlist?list=PL…
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LJI Microscopy Core retweeted
I learned yesterday the video I made in 2017 explaining how Bitcoin works was taken down, and my channel received a copyright strike (despite it being 100% my own content). The request seems to have been issued by a company chainpatrol, on behalf of Arbitrum, whose website says they "makes use of advanced LLM scanning" for "Brand Protection for Leading Web3 Companies" I could be wrong, but it sounds like there's a decent chance this means some bot managed to convince YouTube's bots that some re-upload of that video (of which there has been an incessant onslaught) was the original, and successfully issue the takedown and copyright strike request. It's naturally a little worrying that it should be possible to use these tools to issue fake takedown requests, considering that it only takes 3 to delete an entire channel.
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LJI Microscopy Core retweeted
🚨🔬🤖📜 Paper is out! Introducing the #LiquidEngine and #NanoPyx - novel #AI strategies for accelerating #microscopy that explore how to maximise performance 🚀. Brainchild of @Bruno_MSaraiva, @inesmcunha and @Antonio_DBrito. Faster #SRRF and #eSRRF!! 📰: nature.com/articles/s41592-0…
And to start 2025 strong… Our work #NanoPyx is out in @naturemethods 😍❤️ DOI: doi.org/10.1038/s41592-024-0… #NanoPyx is a Python framework that uses the #LiquidEngine to efficiently accelerate bioimage analysis for any user! (1/n) ⬇️
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LJI Microscopy Core retweeted
SpotMAX, our software tool for analysing multi-dimensional microscopy data, is finally out! 🎉 And conveniently, I just presented it at the #I2K conference 😀 A multi-year-long effort of many great collaborators and users. But what can SpotMAX do? A small thread

ALT SpotMAX examples with C. elegans, smFISH yeast, and telomeres in stem cells.

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LJI Microscopy Core retweeted
Congrats to CBP and O’Brien Lab grad students Jake Roetcisoender and Pierre-Emmanuel N’Guetta for capturing this beautiful image and submitting it for the win!
Replying to @l_obrien_lab
@L_obrien_lab and @P_NGUETTA win @UNC_SOM 2024 Art in Science Competition! This image captures a rare urinary tract defect resulting in ureteral duplication. Read more: unc.live/4ffdHoL View all winning images on the 1st floor of Bondurant Hall this week. #sciArt
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LJI Microscopy Core retweeted
Thrilled to share that "The Ecstasy of Microscopy" has won Best #Documentary Short @RawScienceTV Film Festival. Massive thank you to @LJIMicroCore @ljiresearch for making this film possible. It was a privilege to share the film with an audience of curious minds in New York City.
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LJI Microscopy Core retweeted
Now that the dust has settled..I will say this much, I’m livid. The more I find out about Stefano’s betrayal..the more angry I become. I chaired the search that hired him. We had many other wonderful apps to choose from. The hurt that he caused in Brenda’s lab and his own /1
Science is built on trust. What happens when someone destroys it? My first feature for @_TheTransmitter investigates the emotional and existential fallout for one lab in the aftermath of a misconduct case. thetransmitter.org/science-a…
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