Postdoc @TheCraikGroup | PhD from the @IMBatUQ | with a keen interest in protein engineering and plant synbio 🌱🧬💊
Brisbane, Queensland
- Tweets 52
- Following 473
- Followers 157
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Max Harding retweeted
🌱 RESEARCH 🌱
Bacteriophage P22 Virus-Like Particles as Nanoscale Protein Scaffolds for Plant Synthetic Biology - Harding et al.
🔗 doi.org/10.1111/pbi.70735
#plantscience #syntheticbiology 🧪
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Excited to finally be able to tweet (or whatever X-ing is called) about my first first author paper, now published! We explored using protein cages as tools for encapsulating bioactive peptides which are typically difficult to produce recombinantly.
doi.org/10.1111/1751-7915.70…
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Max Harding retweeted
High-fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages
"Fluorescent dyes, proteins and cytotoxic drug molecules can all be selectively packaged via a peptide-mediated targeting process."
onlinelibrary.wiley.com/doi/…
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Max Harding retweeted
🚀Exciting Opportunity in Peptide Chemical Biology!
We are seeking a domestic #PhD student (ANZ citizens) to join @TheCraikGroup group @IMBatUQ @ARC_CIPPS
For more details and to apply, please visit the following link.
study.uq.edu.au/study-option…
Please share with your network!🙂
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Max Harding retweeted
Enhancing quality and yield of recombinant secretory IgA antibodies in Nicotiana benthamiana by endoplasmic reticulum engineering - #ISPMF @ISPMF
onlinelibrary.wiley.com/doi/…
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Fun times at #ISPMB24 in Cairns. Enjoying being able to share some fun work expressing protein cages in 🌱
CIPPS PhD student @MaxHarding19 highlighting his research at the 13th International Congress on Plant Molecular Biology 🌱
@TheCraikGroup
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Max Harding retweeted
New preprint out @biorxivpreprint. Great work by PhD student Seokmu Kwon (@smkwon6) and postdoc Mike Andreas. Congrats!
biorxiv.org/content/10.1101/…
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Max Harding retweeted
In our article published today @Nature , we report complete all-atom structural models of a fully packaged bacteriophage particle. Congratulations to Kush Coshic on his first publication! Many thanks to Chris Maffeo and David Winogradoff for pushing this 6-year project forward.
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Max Harding retweeted
Coming down from the high of Taylor-related content with the Aus part of the Eras tour now over? I've got you covered.
Introducing:
🔺Tetrahedral encapsulin protein cages (@taylorszyszka's version)
biorxiv.org/content/10.1101/…
Encapsulins form icosahedra. How did she make pyramids?
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What a cool piece of science! Employing sortase A to not only facilitate C-to-C protein ligation but also to achieve an intramolecular protein domain inversion.
onlinelibrary.wiley.com/doi/…
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I'd heard of Arc proteins, but another cool VLP expressed in the brain! 🌐🧠 Will be interesting to follow @AeraTx developments as they leverage these endogenous protein cages for therapeutic applications 🧬
Check out the BEAUTIFUL cryo-EM PNMA2 capsid structure from @SimonErlendsson @BriggsGroup 😍 We include a lot more structural info in this version. /4
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Max Harding retweeted
Join us at the Atrium at UQ Brisbane City on 16 November for cheese and chats, where we will share our vision for addressing global health challenges.
Hear insight into the research from different career perspectives
🔗Register bit.ly/UQEvent
@IMBatUQ @UQ_News @ARC_CIPPS
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Max Harding retweeted
Close up of the newly-infected bacterial cell from "Bacteriophage T4 Infection." I drew the illustration in Photoshop at a scale of 1 pixel/nanometer.
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Max Harding retweeted
Great to get together with over 100 CIPPS Early and Mid- Career Researchers for an inspiring two days of amazing science and mentoring programs in the picturesque Blue Mountains!
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Meanwhile, somewhere in remote FNQ, @PlantDocEd encourages @MarkJackson57 to give it a little touch ☠️
Even in the Poison Garden, this little guy is in isolation.
Why? Because it is one of the most venomous and dangerous plants in the world - if you touch it, the sensation is likened to being burned and electrocuted at the same time, and the effects can persist for YEARS.
a 🧵
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Max Harding retweeted
Our work on antiplasmodial peptide-drug conjugates is out today in @BioconjChem! Congrats to PhD student @Izzy_Palombi for leading the effort, joined by @AndrewWhiteSci & @CaitlinGare, @McmorranBrendan at JCSMR and @NicoleLscientst & @TheCraikGroup at IMB! pubs.acs.org/doi/full/10.102…
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Want to learn about the science of Plant Molecular Farming? 💊🌱 come and hear me talk at the Paddo tomorrow night! 🍺
Join our @IMBatUQ researchers at @pintofscienceAU this coming week! @Clara_J_Jiang, @MaxHarding19 and @LilyKenchEvans will be sharing their work at various beer-serving locations in Brisbane! More details here: imb.uq.edu.au/event/19071/pi…
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Max Harding retweeted
Now in formatted form: "Tunable In Vivo Colocalization of Enzymes within P22 Capsid-Based Nanoreactors"
From co-loading ratios measured by FRET to learning that sometimes less is more for densely packed enzymes!
pubs.acs.org/doi/10.1021/acs…
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