#postdoc positions in our interdisciplinary #cancer #evolution @CEC_ICR lab @ICR_London. Applicants from maths/physics/computer science/quantitative genetics backgrounds are particularly welcomed. Do drop me a line to discuss. jobs.icr.ac.uk/vacancies/538…

I am excited to advertise an opportunity for a scientific officer position to work with me and @trevoragraham to experimentally test predictions about therapy resistance evolution in our group at the @ICR_London, @CEC_ICR Application here: jobs.icr.ac.uk/vacancies/419…

Welcome to the ICR’s GEDy Lab Twitter takeover! In celebration of this year’s Evolution Day, we invite you to a tour of our lab in @CEC_ICR highlighting our work on understanding and tackling cancer evolution. @maxmossner @gcresswell @trevoragraham

How do the #genome, #epigenome and #transcriptome co-evolve in colorectal #cancer? In the second of two papers in @nature, we find gene expr is not strongly heritable & evaluate "driverness" of muts directly in patient tumours nature.com/articles/s41586-0… @AndreaSottoriva #EPICC2 1/7

How do the #genome, #epigenome & #transcriptome co-evolve in colorectal #cancer? In the 1st of 2 studies in @Nature we measure the contribution of #chromatin accessibility in #cancer #evolution. #genetics and #epigenetics interplay! #EPICC1 @trevoragraham nature.com/articles/s41586-0…

The future of UK medical research is at risk, including pioneering projects that I work on for @CRUK_Policy. @HackneyAbbott as my MP, please sign this letter to show your support and help us continue to make progress for patients amrc.org.uk/open-letter-to-t… #ResearchAtRisk

More distraction: new #preprint we posted a little while ago biorxiv.org/content/10.1101/… looks at somatic copy number #evolution in #colorectal #cancer. Suggests a #CNA bottleneck adenoma->cancer, & thereafter CNAs experience #stabilising #selection, remarkably even in mets & chemo.