Med by Cell Press
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Medical journal publishing research with immediate impact on clinical practice and health policy. This account is not monitored, and content is automated.

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Joined December 2019
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Online Now: Pregnancy-associated cardiac complications dlvr.it/TVZZ7Q

Pregnancy-associated cardiac complications

Thordsen and Arany review changes in maternal physiology that occur during pregnancy and highlight how these changes contribute to or exacerbate various common cardiovascular pathologies. They...

cell.com
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Online Now: Mucoadhesive recombinant human catalase for dry eye disease: From protein engineering to first-in-human study dlvr.it/TVYRX3

Mucoadhesive recombinant human catalase for dry eye disease: From protein engineering to first-in...

Shao et al. report a carrier-free enzyme-engineering strategy by thiolation of recombinant human catalase for treating dry eye disease. Such thiolated enzyme with sustained ocular retention shows...

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Online Now: Deep learning-enabled screening of chronic kidney disease from echocardiography dlvr.it/TVXzx5

Deep learning-enabled screening of chronic kidney disease from echocardiography

Chronic kidney disease (CKD) has an underdiagnosis rate of over 60%, and high-risk populations are not routinely screened. Here, Yuan et al. develop and externally validate a deep learning model to...

cell.com
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Online Now: An adult proteomic signature associated with very low birth weight and chronic disease risk dlvr.it/TVWnQJ

An adult proteomic signature associated with very low birth weight and chronic disease risk

Huang et al. identify an adult plasma proteomic signature associated with recalled very low birth weight (VLBW). The index is associated with adult disease burden and subsequent disease risk, but is...

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Online Now: N-of-1 investigational study of a novel antisense oligonucleotide drug in CHCHD10-related ALS shows early signs of efficacy dlvr.it/TVVMgv

N-of-1 investigational study of a novel antisense oligonucleotide drug in CHCHD10-related ALS shows...

Cousin et al. report an individualized antisense oligonucleotide for CHCHD10-related ALS. In one participant, six intrathecal doses were well tolerated, plasma neurofilament light decreased to the...

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Online Now: Prenatal exposure to the plasticizer DEHP increases the likelihood of early-life autism and ADHD symptoms through epigenetic programming dlvr.it/TVRv4k

Prenatal exposure to the plasticizer DEHP increases the likelihood of early-life autism and ADHD...

Tanner et al. show that prenatal DEHP exposure increases autism and ADHD symptoms via epigenetic programming. Using a systems-biology framework, they identified cord blood DNA methylation signatures...

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Online Now: Cardiovascular-kidney-metabolic syndrome and the risk of liver-related and cardiovascular events across the steatotic liver disease spectrum dlvr.it/TVRPhy

Cardiovascular-kidney-metabolic syndrome and the risk of liver-related and cardiovascular events...

Fan et al. show that higher cardiovascular-kidney-metabolic stage is associated with graded increases in both cardiovascular and liver-related events across the steatotic liver disease spectrum....

cell.com
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Online Now: Pomalidomide plus bortezomib and dexamethasone for newly diagnosed multiple myeloma with renal impairment: Randomized phase II study (POM-MM-003) dlvr.it/TVQ8cb

Pomalidomide plus bortezomib and dexamethasone for newly diagnosed multiple myeloma with renal...

Xiao et al. report results of a randomized phase II trial showing that pomalidomide plus bortezomib-dexamethasone (PVd) significantly improves hematologic and renal responses compared with bortezom...

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Online Now: Restoring locomotion in motor-complete spinal cord injury via trunk-mediated control using a commercial epidural spinal cord stimulator dlvr.it/TVNj7m

Restoring locomotion in motor-complete spinal cord injury via trunk-mediated control using a...

Agnesi et al. show that trunk movements can modulate epidural spinal cord stimulation in people with motor-complete spinal cord injury. Trunk extension switches stimulation-induced lower-limb...

cell.com
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Online Now: Adoptive MAIT cell therapy for liver cancer enhanced by multimodal modulation of immune receptors and checkpoints dlvr.it/TVKp5t

Adoptive MAIT cell therapy for liver cancer enhanced by multimodal modulation of immune receptors...

Li et al. developed an optimized ex vivo expansion platform and evaluated cancer-patient-derived MAIT cells for adoptive liver cancer therapy. Antigen stimulation, IL-15, and dual PD-1/TIGIT blockade...

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Online Now: The human oral and airway viral genome catalog from metagenomes enables virome characterization informing respiratory health dlvr.it/TVJWQc
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Online Now: Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy dlvr.it/TV6qgd
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Online Now: Multiomics profiling of plasma reveals lipid-immune dysregulation and exosome remodeling in mpox and mpox-HIV co-infection dlvr.it/TV5g5k
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Discover the Gene Therapy themed collection, bringing together expert Reviews and a Perspective on the scientific progress, ethics, value, and implementation challenges shaping the future of gene therapy. Explore the collection: hubs.li/Q04tmMHk0
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Online Now: A bimodal large language model reduces misalignment in patient education: A double-blinded randomized trial dlvr.it/TV4wPR
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Online Now: Concomitant lipid-lowering and anticoagulation therapy for recurrent venous thromboembolism prevention: A Bayesian meta-analysis dlvr.it/TV4HpF

Concomitant lipid-lowering and anticoagulation therapy for recurrent venous thromboembolism...

A Bayesian meta-analysis of 28 randomized and observational studies suggests that concomitant use of anticoagulant and lipid-lowering therapy may reduce recurrent venous thromboembolism risk beyond...

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Online Now: Adjuvant oxaliplatin with S-1 (SOX) versus S-1 for stage II–III gastric cancer (CAPITAL): A randomized, open-label, phase 3 trial dlvr.it/TV1ygT
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Online Now: Ketamine assisted psychotherapy to reduce chronic neuropathic pain: A mixed-methods randomized pilot trial dlvr.it/TV1TNQ
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Online Now: Engineered mesenchymal stem cells regulate integrated stress response for fibrosis therapy dlvr.it/TV0G5d

Engineered mesenchymal stem cells regulate integrated stress response for fibrosis therapy

Yu et al. develop an engineered mesenchymal stem cell-liposome conjugate that homes to fibrotic lesions and releases ISRIB and NMN in response to reactive oxygen species. This platform regulates...

cell.com
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Online Now: Plasma proteomics linking primary and secondary diseases: Insights into molecular mediation from UK Biobank data dlvr.it/TTs8WM
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