MOBILion’s tech separates and analyzes challenging molecules with higher resolution, faster analysis, and simpler workflows—advancing safer, effective therapies
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100K 🏃♂️ That’s not a typo! Congratulations to MOBILion’s David Mastrippolito on completing the Boulder Field 100K at Hickory Run State Park. Dave tackled two 50K trail loops and finished 10th overall and 5th in his age group. Way to go, Dave! 👏
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Finding PFAS isn’t enough, you need evidence to trust the result.
FluoroMatch IM combines ion mobility, CCS and accurate mass to prioritize likely PFAS in complex data, with a 5% false-positive rate, even without MS/MS or retention time data.
Read more: pubs.acs.org/esthag/article/…
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Has mass spectrometry reached a software tipping point?
MOBILion’s Melissa Sherman and Frederick Strathmann discuss why better software, AI and higher-quality data will shape what comes next.
Read more: technologynetworks.com/analy…
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Two new approaches. One goal: deeper, faster proteome profiling.
At #HUPO2026, CTO Daniel DeBord presents two posters on high-resolution ion mobility for proteomics:
🔬 PS03.174 | 2–3 PM
🔬 PS03.175 | 1:15–2:15 PM
📅 Sept. 30 | Poster Session 3
#Proteomics #IonMobility
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SLIM can do more than create long separation paths. A parallel-path SLIM–QQQ architecture achieved up to 100% duty cycle and improved detection limits 1.5–3×—helping lay the foundation for PAMAT.
sciencedirect.com/science/ar…
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What if you could increase acquisition speed without sacrificing high-resolution separation?
SLIM’s High Duty Cycle design interleaves ions across two ~12 m paths, increasing MS1/MS2 acquisition from 1.25 to 2.15 Hz. At 200 samples/day, that delivered 66% more points per LC peak.
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What can PFAS isomers reveal about environmental contamination?
At #AWMA2026, Sarah Choyke of Eurofins will share how HRIM distinguishes branched and linear PFAS isomers to strengthen identification and quantitation.
📅 Sept. 22 | 4:45–6:15 p.m.
📍 Durham, NC
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Different labs. Operators. Instruments. Remarkably consistent CCS.
Across 4 labs and 250 lipid features, SLIM-based HRIM produced an average interlaboratory RSD of ~0.1%, reproducible structural measurements that strengthen identification confidence.
pubs.acs.org/jamsef/article-…
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Where are the greatest opportunities for innovation in mass spectrometry?
MOBILion executives Melissa Sherman and Frederick Strathmann share how simpler workflows, better separations and higher-quality data can expand what scientists can discover.
technologynetworks.com/tn/ar…
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Hear John McLean, PhD, at #ISC2026 in Prague!
Keynote: Rapid High-Dimensional Phenomics Using LC–Ion Mobility–MS
📅Sept. 8, 8:30 a.m.
Tutorial: A Practical Guide to LC-IM-MS
📅 Sept. 9, 4:30 p.m.
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Detecting a steroid is only half the challenge. New research from Clemson shows how chemical derivatization and HRIM-MS can help distinguish structurally similar 11-oxosteroids using mass, CCS and mobility fingerprints.
Read more: pubs.acs.org/amachv/article-…
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Same mass. Same molecular connectivity. Potentially very different biological effects.
Vanderbilt researchers used chiral complexation to make enantiomers distinguishable, then MOBILion HRIM to rapidly separate and measure them.
Full application note: view-su2.highspot.com/viewer…
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Huge congratulations to Jennifer Krone for competing at the 2026 USA Triathlon Nationals in Milwaukee! 🎉 Jen tackled the Sprint’s swim, bike and run while managing a shoulder injury. We’re proud to celebrate her determination at MOBILion. Way to go, Jen!
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More peptide IDs only matter if we can trust them.
Our Proteomics paper shows adding SLIM HRIM to quadrupole isolation reduced simulated chimeric precursor group size by 13× and produced cleaner spectra with less background, strengthening confidence in deeper DIA discoveries.
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Cleaner spectra mean fewer interferences, greater confidence, better quantitation, and more usable information.
By separating and manipulating ions before mass analysis, SLIM improves data at the source, creating a stronger foundation for advanced informatics and AI.
Read Below.
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Read the full article here: lab-innovations.com/2026/08/…
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Austin Anderson of @LosAlamosNatLab is presenting at #ACSFall2026!
Learn how high-resolution ion mobility helps separate Irganox from its degradation products.
📅 Aug. 27
⏰ 11:25 a.m. CDT
📍 Room S404d, McCormick Place
Connect with Austin at the conference!
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As small-molecule drugs grow more complex, rapid chiral analysis is essential. Vanderbilt and Pfizer used HRIM-MS to resolve 7 of 8 enantiomer pairs on a millisecond timescale, over 1,000× faster than traditional chiral chromatography.
Read the paper: pubs.acs.org/ancham/article/…
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Small structural differences can have major effects in drug development. Vanderbilt researchers Ben Blakley, Allison Reardon, Jody May & John McLean used MOBIE® HRIM-MS to reveal unexpected dimers, trimers and reversed arrival order in drug isomers. More: view-su2.highspot.com/viewer…
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