👩🔬 Scientist | 🔬 Immunology | 📍Genmab
Amsterdam, Nederland
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Very happy to share with you an amazing piece of work on gamma delta T cells published today in @Nature. Thanks to a huge team effort by @deMirandaLab @NFdeMiranda Emile Voest Frits Koning @MyriamChalabi @jorisvandehaar @vivienveninga from @LUMC_Leiden and @NKI_nl
It’s finally out! Our most recent work published today in @Nature:
γδ T cells are effectors of immunotherapy in cancers with HLA class I defects.
nature.com/articles/s41586-0…
🧵below 👇👇👇
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Natasja de Vries retweeted
Out today: our news & views in Nat Immunol on the recent (and excellent) Nature paper by Voest & @NFdeMiranda teams: nature.com/articles/s41590-0…
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Natasja de Vries retweeted
Wonderful N&V in @NatImmunol by actual #gdTcell experts @BSilva_Santos and S. Mensurado (thank you!), inspired by our recent work. It's amazing to see the ethusiasm from the #gdTcell community.
#cancer #immunotherapy nature.com/articles/s41590-0…
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Natasja de Vries retweeted
SPOTLIGHT:@NLdeVries @jorisvandehaar @vivienveninga @MyriamChalabi demonstrated that γδ T cells contributed to the response to immune checkpoint blockade in patients with β2-microglobulin-negative DNA mismatch repair-deficient colon cancers 👉 ow.ly/9f9w50MN96V
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Natasja de Vries retweeted
γδ T-cells are effectors in MMRd cancers with B2M loss from Voest lab in Nature nature.com/articles/s41586-0…
A hell of a paper - maybe THE paper of 2023, although I am conscious I am sticking my head out saying this in February. Reasons are.... 1/2
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Natasja de Vries retweeted
This week: A team at @LUMC_Leiden showed that γδ #Tcells can detect cancer cells that are "invisible" to other T cells.
@NLdeVries @jorisvandehaar @vivienveninga @MyriamChalabi
📝 go.nature.com/3IGGxRR
▶️ bit.ly/3WX1Ty3
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Natasja de Vries retweeted
γδ T cells unveil invisible tumors dlvr.it/Sj2PPV #immunology
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Natasja de Vries retweeted
γδ T cells mediate immunotherapy responses when cancers lack MHC class I dlvr.it/ShpS8W
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Natasja de Vries retweeted
Cancer Discovery #ResearchWatch:
γδ #TCells Mediate Immunotherapy Response in HLA Class I–Deficient Cancers, summarizing the work of @NLdeVries, @jorisvandehaar, @vivienveninga, @MyriamChalabi, @NFdeMiranda, Emile E. Voest, et al.
bit.ly/3XuPEdc
@NKI_nl @LUMC_Leiden
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Natasja de Vries retweeted
Wetenschappers van het LUMC en het @hetAVL ontdekten hoe gespecialiseerde #immuuncellen in staat zijn tot het opsporen en verwijderen van #tumoren, die ‘onzichtbaar’ zijn voor de conventionele verdedigingsmechanismen van het #immuunsysteem 👇 @Nature lumc.nl/over-het-lumc/actuee…
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Immune checkpoint blockade responses in HLA class I-negative cancers explained below 👇👇👇
Nature research paper: γδ T cells are effectors of immunotherapy in cancers with HLA class I defects go.nature.com/3W6V3pl
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Natasja de Vries retweeted
New #JITC article: Local and systemic immune profiles of human pancreatic ductal adenocarcinoma revealed by single-cell mass cytometry bit.ly/3nIyl85 @NFdeMiranda @NLdeVries
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Natasja de Vries retweeted
Congrats @NLdeVries and Thomas Brouwer. It was a painstaking work to collect and profile several tissues derived from #PancreaticCancer patients to resolve systemic and local immune profiles. Several leads discovered here will keep the lab busy for years to come!
The most recent paper from the lab has been published at @jitcancer. We employed single-cell mass cytometry to delineate tumor-associated and systemic immune profiles in #PancreaticCancer.
jitc.bmj.com/content/10/7/e0…
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Happy to share our latest paper in @jitcancer with @deMirandaLab: comprehensive analysis of local and systemic immune profiles in patients with PDAC. Our findings encourage further investigation of the role of ILC1-like cells and B cells in PDAC. To read: jitc.bmj.com/content/jitc/10…
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Natasja de Vries retweeted
The most recent paper from the lab has been published at @jitcancer. We employed single-cell mass cytometry to delineate tumor-associated and systemic immune profiles in #PancreaticCancer.
jitc.bmj.com/content/10/7/e0…
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Natasja de Vries retweeted
Check our pre-print: gd-T cells are effectors of #immune #checkpoint blockade #immunotherapy in #colorectal #cancer. Great collaboration between @deMirandaLab and Voest lab @LUMC_Leiden and @NKI_nl. @NLdeVries @jorisvandehaar @VeningaVivien @MyriamChalabi
biorxiv.org/cgi/content/shor…
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gd T cells are effectors of immune checkpoint blockade in MMR-deficient colon cancers with antigen presentation defects: biorxiv.org/content/10.1101/… Great team effort of @deMirandaLab @jorisvandehaar @VeningaVivien #colorectalcancer #gdTcells #immunotherapy #checkpointblockade
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I’m happy to share with you our review on the integration of genomic and cytometric approaches to study the cancer microenvironment in detail, now published in @FrontOncology with @ahmedElkoussy @NFdeMiranda @deMirandaLab Frits Koning frontiersin.org/articles/10.…
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Interested in #colorectalcancer #immunology #genomics #immunotherapy? Follow our Immunogenomics Lab @deMirandaLab for our latest research and activities! @LUMC_Leiden
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Natasja de Vries retweeted
We can find anti-cancer immune responses in #colorectalcancer patients that are currently not considered for #Immunotherapy Congratulations to @JvandenBulk et al. for a lot of work Next step: develop specific approaches for these patients! genomemedicine.biomedcentral… @GenomeMedicine
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