Nature Microbiology@NatureMicrobiol

Nature Microbiology publishes the latest research and commentary in all areas of microbiology. Now also at bsky.app/profile/naturemicro…

nature.com/nmicrobiol/
Joined February 2015
1,861 Photos and videos
The September issue is now online! Read about: 🔧Microbial engineering 📚FAIR microbial collections 🔄Crossfeeding in soil 🍄Candida virulence 🛡️Antiviral defenses in bacteria 🦠Giant virus catalogue 🦟Plasmodium surviellance 💉Measles and much more! nature.com/nmicrobiol/volume…
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Nature Microbiology retweeted
Alexander Harms@AHarms485
Sep 25
The final version of our manuscript on TnSeq in bacteriophages (“HIDEN-SEQ”) is out today – if you have an interesting phage phenotype and want to know the underlying genetic basis, this one is for you! 1/3
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Defining the essential genome of diverse phages with phage Tn-seq dlvr.it/TVdsZJ #MicroSky

Defining the essential genome of diverse phages with phage Tn-seq

Nature Microbiology - Phage Tn-seq uses Tn5 transposon mutagenesis with anti-CRISPR-based selection and deep sequencing as a method to generate unbiased, genome-wide mutations across diverse phages

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Systematic mapping of bacteriophage gene essentiality with HIDEN-SEQ dlvr.it/TVdsTj #MicroSky

Systematic mapping of bacteriophage gene essentiality with HIDEN-SEQ

Nature Microbiology - HIDEN-SEQ (hidden Acr-enabled transposon-insertion sequencing) is a transposon-insertion sequencing method for phages that systematically links their genes to selectable...

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Nature Microbiology retweeted
ISGlobal
@ISGLOBALorg
Sep 24
🦟 When conditions become unfavourable, the malaria parasite can change strategy. An #ISGlobal-led study uncovers the molecular mechanism that allows Plasmodium falciparum to respond to stress by increasing the production of forms needed for mosquito transmission. Published in @NatureMicrobiol, the study identifies AP2-HS as a key regulator of this response. 🔗 Read more: isglobal.org/en/-/un-nuevo-e… @CaixaResearch #Malaria #GlobalHealth
The malaria parasite is able to detect changes in its host’s environment and respond by increasing the production of sexual forms capable of being transmitted to mosquitoes.

ALT The malaria parasite is able to detect changes in its host’s environment and respond by increasing the production of sexual forms capable of being transmitted to mosquitoes.
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Pseudomonas aeruginosa induces the generation of pathogenic IFNγ+Th17 cells that promote lung damage and chronic inflammation in cystic fibrosis dlvr.it/TVd1lT #MicroSky

Pseudomonas aeruginosa induces the generation of pathogenic IFNγ+Th17 cells that promote lung...

Nature Microbiology - Pseudomonas aeruginosa drives harmful immune responses in cystic fibrosis by reprogramming protective Th17 cells into pathogenic populations that damage lung tissue and...

nature.com
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AP2-HS and a GDV1 regulatory feedback loop mediate environmental induction of sexual conversion in Plasmodium falciparum dlvr.it/TVWjPc #MicroSky

AP2-HS and a GDV1 regulatory feedback loop mediate environmental induction of sexual conversion in...

Nature Microbiology - This study describes the complex transcriptional regulatory mechanism enabling fine-tuned and rapid regulation of Plasmodium falciparum investment in transmission under...

nature.com
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Sequential gene loss promotes expansion of monophasic Salmonella Typhimurium ST34 dlvr.it/TVWjGh #MicroSky

Sequential gene loss promotes expansion of monophasic Salmonella Typhimurium ST34

Nature Microbiology - Genomic and functional analyses reveal sequential gene loss events affecting dinB and fljB in monophasic Salmonella Typhimurium ST34 conferring a competitive advantage during...

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In vivo CRISPRi screens reveal Escherichia coli functional adaptations in the mouse gut dlvr.it/TVWj9t #MicroSky

In vivo CRISPRi screens reveal Escherichia coli functional adaptations in the mouse gut

Nature Microbiology - In vivo silencing of genes in E. coli strains using CRISPRi reveals specific genetic factors and metabolic adaptations that influence colonization in the mouse gut under...

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Functional capacities drive recruitment of bacteria into plant root microbiota dlvr.it/TVWj6J #MicroSky

Functional capacities drive recruitment of bacteria into plant root microbiota

Nature Microbiology - Functional versatility plays a key role in shaping root microbiota.

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Bacterial growth rate in populations and single cells dlvr.it/TVWhxZ #MicroSky

Bacterial growth rate in populations and single cells

Nature Microbiology - In this Perspective, Levin and Wang give a brief history of bacterial growth rate and discuss how it is connected to nutrient availability and macromolecule synthesis, with a...

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Convergent use of aminopeptidase N receptor by hedgehog merbecoviruses dlvr.it/TVVzJL #MicroSky

Convergent use of aminopeptidase N receptor by hedgehog merbecoviruses

Nature Microbiology - Hedgehog merbecoviruses are shown to use aminopeptidase N as a functional receptor through a distinct binding mode, revealing convergent receptor usage among merbecoviruses.

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Aminopeptidase N is a receptor for hedgehog merbecoviruses dlvr.it/TVVzCx #MicroSky

Aminopeptidase N is a receptor for hedgehog merbecoviruses

Nature Microbiology - Hedgehog merbecoviruses utilize hedgehog aminopeptidase N, but not the human orthologue, as their entry receptor. Structural resolution of the glycoprotein–receptor...

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Prophage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection in mice dlvr.it/TVVz5f #MicroSky

Prophage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection...

Nature Microbiology - An engineered non-pathogenic bacterium produces lytic phages and is protective in mouse models of Salmonella infection.

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Ambient temperature is encoded in the metagenome of microbial communities dlvr.it/TVV552 #MicroSky

Ambient temperature is encoded in the metagenome of microbial communities

Nature Microbiology - Environmental temperature can be accurately inferred from the DNA composition of microbial communities across marine and soil ecosystems, using machine learning and based on...

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Cryo-EM structures of Candida albicans chitin synthase Chs1 reveal a druggable translocation channel dlvr.it/TVV4zN #MicroSky

Cryo-EM structures of Candida albicans chitin synthase Chs1 reveal a druggable translocation channel

Nature Microbiology - Structures of Candida albicans class II chitin synthase reveal mechanisms of oligosaccharide translocation and inhibition. The translocation channel is a class II-specific...

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Evidence of direct methane production from long-chain fatty acids by thermophilic Archaeoglobi dlvr.it/TVV4sF #MicroSky

Evidence of direct methane production from long-chain fatty acids by thermophilic Archaeoglobi

Nature Microbiology - An enrichment culture from hot spring sediments in China suggests that Ca. M. sphaerolipidus uses a suite of metabolic pathways to convert long-chain fatty acids such as oleic...

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Histone H2B monoubiquitination drives sexual commitment in malaria parasites dlvr.it/TVV4jk #MicroSky

Histone H2B monoubiquitination drives sexual commitment in malaria parasites

Nature Microbiology - The Rad6B–Tex1 ubiquitination complex drives malaria parasite sexual commitment by monoubiquitinating histone H2B, and thereby enabling gametocyte formation and mosquito...

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Translating soil microbiome knowledge into agricultural decisions dlvr.it/TVTXfR #MicroSky

Translating soil microbiome knowledge into agricultural decisions

Nature Microbiology - To successfully translate microbiome knowledge into practical interventions for farmers, research must be designed with agriculture in mind and shift from retrospective...

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Modelling air pollution impacts on infectious disease dlvr.it/TVTXbs #MicroSky

Modelling air pollution impacts on infectious disease

Nature Microbiology - Air pollution increases the risk of invasive pneumococcal disease and bacterial lineage changes the timing of that risk, making pathogen genomic diversity an effect modifier.

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Pneumococcal population structure influences the effects of air pollution on invasive disease risk in South Africa dlvr.it/TVTXXq #MicroSky

Pneumococcal population structure influences the effects of air pollution on invasive disease risk...

Nature Microbiology - Air quality and climate factors alter the risk of invasive pneumococcal diseases such as meningitis. Importantly, the lineage and serotype (population structure) of...

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