Tweets from lab members of the Epitranscriptomics & RNA Dynamics lab @CRGenomica

Barcelona, Spain
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It was a pleasure hosting Jasper Verwilt @JVerwilt from Sleegers Lab @SleegersLab in our lab for 3 weeks, focusing on establishing a Nano3PCR-seq protocol to capture cell-free RNA biomarkers in human biofluids — Jasper it was great having you with us, hope to see you again!🚀
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(6/8) Under basal conditions, the ribosome-associated tRNA pool largely matches the total cellular tRNA pool. But under stress, the picture changes... have a look at the paper to see how.
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(4/8) tRIBO-seq builds on RiboLace technology from to pull down active ribosomes. Using ~15× less starting material, we recover comparable ribo-tRNA amount to polysome purification - with a much faster protocol. And yes, recovered tRNAs correlate well with the polysome-derived.
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New preprint released 🪇 Which tRNAs are used by ribosomes during translation? We introduce tRIBO-seq, a nanopore method to sequence ribosome-associated tRNAs and track how the active tRNA pool changes across stress conditions. biorxiv.org/content/10.64898… A thread 🧵
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Please join us in congratulating Gregor @GDiensthuber on successfully defending his PhD 🎓 A proud moment for the whole lab 🧬 Thanks for being such a great colleague and lab mate! We’re excited to see where your science takes you next! 🚀
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Last week our Lab participated in the @CRGenomica PhD Symposium! Huge congrats to Cristina Petrella and Leda Katopodi for their successful talks, and @GDiensthuber for reaching the final stage of his PhD! Big thanks to the CRG and the PhD community for a science-packed event👏
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It was our pleasure to host James Bryson (BRIC, Copenhagen) at @CRGenomica through the EU-LIFE Postdoctoral Exchange Program! Thanks to James for presenting his work on advanced CRISPR tools for epitranscriptomic research, and to @EULIFE_news for this opportunity!🧬✈️#EULIFE #CRG
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🧬 New review on nanopore base-calling models is out! Congrats to Sonia Cruciani (former Novoa Lab PhD, now postdoc at the Deplancke Lab, EPFL) and @EvaMariaNovoa 📖 Read it here:nature.com/articles/s41580-0… 👏👏👏
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🧬Novoa Lab had a great time at the Genome Biology Program Retreat'25! Big thanks to the organisers for such an inspiring and fun event 👏 Congrats to @mie_monti for being part of the organising team and to @oguzhanbegik for giving a fantastic talk!
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Novoa Lab joined the PRBB Open Day 2025🔬🧬🌊 @the_prbb to share our passion for RNA research with the public. Thanks to everyone who came to explore science with us and thanks organisers for making this event possible! #PRBBOpenDay #OpenScience
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Last month, the @NovoaLab attended the Premis Nacionals de Recerca ceremony to celebrate @EvaMariaNovoa receiving the National Young Researcher Award!🎉👏 Huge congratulations again, Eva - an incredible and well-deserved recognition! 🧬🏆
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Just wrapped up an amazing lab retreat! 🌟 Huge thanks to everyone who made it unforgettable. Your dedication, creativity, and camaraderie truly shine through. Excited for the science ahead! Thanks to @EMBO_YIP for making this possible 🔬🧪
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And thank you to our wonderful collaborators, colleagues, families and friends who without your support, this would not be possible ❤️❤️❤️
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Or catch the @bioprotocolbyte webinar on nano-trnaseq and other @nanopore direct RNA sequencing advances from us at the Novoa Lab with @MorghanLucas and @IvanBeki in September 🧑‍💻👩‍💻 register here bio-protocol.org/webinar/det…
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The method is also available as a service and soon-to-be kit from our amazing colleagues at @ImmaginaBiotech who have been working with Novoa Lab to further improve the method immaginabiotech.com/our-tech… 🧑‍🔬
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Congratulations to @EvaMariaNovoa @MorghanLucas and @LeszekPryszcz from @CRGenomica for being awarded the prize of Best Scientific Article from the Catalan Society of Biology @SCB_iec on their @nanopore method for sequencing native tRNAs and their modifications 🎉🎉🎉🎉
🏆@EvaMariaNovoa, investigadora al @NovoaLab ha rebut el #PremiSCB2024 a l’#ArticleCientífic pel treball “Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing” #NitBio2024 #PremisSCB2024
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Be your model organism: We have successfully adopted a high-fat diet going into 2024 #LabSnacks #FuelofChampions
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Check out our latest preprint! m6A basecalling from direct RNA nanopore data at single nucleotide and single molecule resolution!!!
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The current issue of @NAR_Open is featuring @hatahini's visualization of our results on ribosome-mitochondria interactions! Thank you very much for this awesome image Hassan!
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Congratulations to @MorghanLucas and @oguzhanbegik who won poster prizes at the @RNASociety #RNA23 conference in Singapore!
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