PMWC 2027 program framework is FINAL. Exciting additions: First, a NEW three-day program spanning translational omics, spatial biology, precision immunology, and precision neurology & neurodegeneration. Second, Nobel Laureate Emmanuelle Charpentier will receive the inaugural J. Craig Venter Visionary Award for helping open the era of programmable biology! And we are bringing back the Atul Butte Company Competition! PMWC 2027 will feature five tracks and 15 programs across three days: TRACK 1: NEXT GENERATION THERAPEUTICS With Nobel Laureates Emmanuelle Charpentier and Randy Schekman, Katy Rezvani, Antoni Ribas, Marcela Maus, David Miklos, Razelle Kurzrock, Cindy Perettie, Frederick Locke, Jay Bradner & Adrian Krainer. The focus: off-the-shelf cell therapies, solid tumor failure, post-PD-1 immunotherapy, bispecifics and ADCs, AI-enabled development, genome/ RNA editing, and N-of-1 medicines. TRACK 2: AI & COMPUTATIONAL MEDICINE With Nobel Laureate David Baker, Andrew Ng, Daphne Koller, Ziad Obermeyer, Marina Sirota and John Halamka. The focus: multimodal diagnostics, computational pathology, foundation models, AI agents in clinical workflows, clinical decision support, real-world evidence, AI safety and AI-driven drug discovery. TRACK 3: PRECISION DIAGNOSTICS With Mary-Claire King, Rebecca Fitzgerald, Nickolas Papadopoulos, Sarah-Jane Dawson, Max Diehn, Joe DeRisi and Alexandre Loupy. The focus: early cancer detection, liquid biopsy, MRD, therapy selection from blood, fragmentomics, transplant monitoring, infectious disease and blood-based diagnostics beyond cancer. TRACK 4: INTEGRATED PRECISION MEDICINE With Eric Lander, Wendy Chung, Lee Hood, Victor Dzau, Hal Paz, Nir Barzilai, Andrea Maier, Michael Snyder and Alexander “Zan” Fleming. The focus: rare-disease diagnosis, population screening, long-read sequencing, health-system implementation, reimbursement, GLP-1 biology, digital biomarkers, prevention and healthspan. TRACK 5: TRANSLATIONAL OMICS, SPATIAL BIOLOGY, PRECISION IMMUNOLOGY & PRECISION NEUROLOGY & NEURODEGENERATION With Nobel Laureate Thomas Südhof, Sarah Teichmann, Aviv Regev, Garry Nolan, Alex Shalek, Miriam Merad, Jeffrey Bluestone, Li-Huei Tsai, David Holtzman and Henrik Zetterberg. The focus: single-cell and spatial atlases, spatial biology in clinical practice, immune reset for autoimmune disease, CAR-T and Treg approaches, Alzheimer's blood tests, neurodegeneration biomarkers and AI-powered neurological diagnostics. PMWC 2027 program: lnkd.in/gPtkWZbQ Which of these platforms will reach patients at scale first? Comment below/repost to help spread the word. Our partnership with Life Science Connect is extending PMWC’s reach to the scientists, clinicians, and industry leaders working across these fields every day. Together, we are giving greater visibility to the people and ideas moving precision medicine forward! #PMWC27 #PrecisionMedicine #ClinicalAI #Biotechnology #Genomics @cindy_perettie @miriammerad @SnyderShot @AlexandreLoupy @sinaihealth @UCJointCPH @msirota84 @Dr_R_Kurzrock

The day closes with scaling AI beyond pilots: Jadwiga Bienkowska of @pfizer, Vinayagam (Vinu) Arunachalam of Takeda and Robert Piskol of @genentech. The hard part is not the pilot. It is enterprise deployment. 5/6

Then the uncomfortable questions. AI Safety, Governance and Evaluation: Danton Char, @bandersmd, @oziadias and Julia Adler-Milstein. Who is accountable? How do we evaluate? Who monitors drift? When do humans override? @StanfordMed @UCSF 4/6

Jan 28, Clinical AI, is chaired by Vincent Liu, with John Halamka opening the day. AI Agents in Clinical Workflows: Ashley Beecy, @ShivdevRao, Munjal Shah, @vivnat and Mohsen Hejrati. @PermanenteDocs @MayoPlatform @SutterHealth @AbridgeHQ 3/6

Who validates each action? When can an agent proceed without a human? Who detects drift? Who can stop it? At the Precision Medicine World Conference (#PMWC27), clinical AI leaders will tackle them. Jan 27–29, 2027 | Santa Clara pmwcintl.com/program/ 2/6

SonoThera Closes Oversubscribed $125 Million Series B Financing to Advance Clinical Development of Ultrasound-Mediated Nonviral Genetic Medicines - businesswire.com/news/home/2…

I enjoyed speaking at #PMWC2026 on the transition from data to knowledge. We’re using foundation models like UCE and Transcriptformer to move beyond the "parts list" toward true clinical digital twins. As Sydney Brenner said: “Don't confuse data with knowledge.”

Our Chief Data Officer introduced #EpiSwitchOrion at #PMWC2026—#OBD's groundbreaking platform to unlock clinical value hidden in #genomic data. Orion is powered by a model built on our deep expertise—core regulatory logic in the 'dark genome'. Book a demo: episwitchorion.com

🚨The Chinnaiyan Lab/Michigan Center for Translational Pathology has officially joined the science Twitter/X world! 🚨 We are excited to share news from our lab and engage with the physicians/scientists worldwide. Run by Chinnaiyan Lab members

23andMe Research Institute left @PMWCintl feeling energized. Science is moving faster than ever, but our mission remains the same: helping people access, understand, and benefit from the human genome. Thanks to the PMWC team for another great year.

Our cofounder & CTO Zack Ziegler keynoted @PMWCintl yesterday. His talk started from one fact: ~half of US physicians use OpenEvidence. How do we do good for the world in ways that are only possible because of the scale of usage? His closing thought: "In 2024 and the first half of 2025 we saw the linear impact regime of AI in healthcare. At the scale we are at today, we have entered the super-linear regime, where increased adoption leads to better outcomes with impact that contributes more than the sum of its parts." The most interesting part of the story is about to start.

“If we can help by ... being the conduit between people who care and the entire research world that's looking to make discoveries, I think we can massively accelerate our pace of research," says @annewoj23 about the 23andMe Research Institute during @PMWCintl panel.

“Will all the intelligence in this room be reproducible by AI by 2030?” The opening question fr @vkhosla in fireside chat w @gdb, @OpenAI @PMWCintl Brockman’s answer: “Yes and no.” Discussion on AI, medicine, and future of expertise. 🧵

Honored to receive the luminary award from the @PMWCintl. Thank you!

💡Sanford Stem Cell Innovation Center Deputy Director Alexis Komor, PhD, was honored Friday w/the @PMWCintl Luminary Award for co-inventing #CRISPR base editing. 🌟 SSCI Director Catriona Jamieson, MD, PhD, received the award in 2024. @KomorLab @thejamiesonlab @ucsdbiosciences

📢 Meet Vazyme at PMWC 2026 🗓 March 4–6 📍 Santa Clara Convention Center 🔬 Booth A409 Discover our full-flow enzyme solutions for mRNA production — from template linearization to IVT, capping & tailing. ✨Let’s connect in Santa Clara. #PMWC2026 #mRNA #Biotech #LifeScience

Meet our experts at Precision Medicine World Conference 2026! Schedule a meeting: na2.hubs.ly/H03XNtN0 Join us in Santa Clara, March 4–6, 2026, to see how Excelra integrates biology, chemistry & AI to advance precision medicine and drug discovery. #PMWC2026 #Excelra

#Today at Precision Medicine World Conference #PMWC2026 @ 2pm PT! Come listen to how Dxcover is translating its multiomic approach into real-world research and clinical impact. dxcover.com/contact-us/ #CancerDiagnostics #EarlyDetection #LiquidBiopsy #AIHealthcare #MedTech