Aging Papers@PapersAging

Sharing quality content from leading journals, reflecting the latest trends in the field of Aging. Since Nov 2023.

Joined November 2023
Frailty, polypharmacy, deprescribing and 23-hour activity: insights from a mouse model academic.oup.com/biomedgeron…

Frailty, polypharmacy, deprescribing, and 23-hour activity: insights from a mouse model

Abstract. Management of older people with frailty commonly includes polypharmacy and deprescribing. The impacts of frailty on the outcomes of medication us

academic.oup.com
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Personalizing cancer care for older adults academic.oup.com/biomedgeron…

Personalizing cancer care for older adults

Cancer is often a disease of aging, and older adults are a heterogenous population that often faces unique challenges when it comes to cancer treatment.1 T

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Circulating biomarkers in older adults with and without sarcopenia: a systematic review and meta-analysis academic.oup.com/biomedgeron…

Circulating biomarkers in older adults with and without sarcopenia: a systematic review and...

AbstractBackground. Sarcopenia, the age-related loss of muscle mass and strength, poses a significant health and economic burden. This systematic review an

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2
State Racism Index and physical function: The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study academic.oup.com/biomedgeron…

State Racism Index and physical function: The REasons for Geographic and Racial Differences in...

AbstractBackground. Structural racism contributes to health inequities in the United States. This study aimed to quantify the association between state rac

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3
Baseline Plasma Growth-differentiation Factor 15 and Recovery of Physical Function Following Total Knee Replacement in the Study of Physical Resilience and Aging academic.oup.com/biomedgeron…

Baseline Plasma Growth-differentiation Factor 15 and Recovery of Physical Function Following Total...

AbstractBackground. Growth-differentiation factor 15 (GDF15), a cytokine with the ability to regulate metabolic and inflammatory activity, is negatively as

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Establishing bone tissue level changes associated with cognitive impairment academic.oup.com/biomedgeron…

Establishing bone tissue level changes associated with cognitive impairment

Abstract. Alzheimer’s disease (AD) and osteoporosis are common chronic conditions of aging. Although several studies have reported an association between t

academic.oup.com
Leisure-time physical activity and metabolomic trajectories over the transition from late midlife to old age academic.oup.com/biomedgeron…

Leisure-time physical activity and metabolomic trajectories over the transition from late midlife...

Abstract. Physical activity may counteract aging-associated disruptions in the metabolome. We investigated how leisure-time physical activity (LTPA) associ

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Associations of Accelerometry-Derived Time in Major Activity Intensities with Cognitive Outcomes: A Compositional Data Analysis Approach academic.oup.com/biomedgeron…

Associations of accelerometry-derived time in major activity intensities with cognitive outcomes: a...

AbstractBackground. Physical activity (PA), sedentary behavior (SB), and sleep are modifiable lifestyle factors linked to cognitive health. Prior research

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High Frailty Index Scores Predict Mortality and Changes in Blood-Based Biomarkers in Aging Female Mice academic.oup.com/biomedgeron…

High frailty index scores predict mortality and changes in blood-based biomarkers in aging female...

Abstract. Variability in aging rates can be quantified with a frailty index (FI) based on the accumulation of clinically evident health deficits in aging m

academic.oup.com
Using case-mixes to understand health resource utilization trajectories among older adults at high risk of falls who received baseline geriatrician-based falls prevention clinic care academic.oup.com/biomedgeron…

Using case-mixes to understand health resource utilization trajectories among older adults at high...

AbstractBackground. We identified case-mixes among older adults at high risk of future falls, determined by longitudinal health resource utilization (HRU)

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Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of aging academic.oup.com/biomedgeron…

Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of aging

Abstract. Aging is associated with many chronic conditions that increase morbidity and mortality. These include obesity, diabetes, sarcopenia, osteoporosis

academic.oup.com
Untargeted Metabolomics Reveals Effects of Calorie Restriction on Skeletal Muscle in Older Female and Male Rats academic.oup.com/biomedgeron…

Untargeted metabolomics reveals effects of calorie restriction on skeletal muscle in older female...

Abstract. This study used untargeted metabolomics to investigate how calorie restriction (CR) affects skeletal muscle in older female and male rats. Fische

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Interventions that prolong multidimensional indicators of healthspan in humans: a systematic review of randomised controlled trials academic.oup.com/biomedgeron…

Interventions that prolong multidimensional healthspan in humans: a systematic review of randomized...

Abstract. Maximizing healthspan, the period of life spent in good health, is a public health priority. This review aimed to summarize the current evidence

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Uric Acid to HDL-C Ratio as a Novel Biomarker for Sarcopenia: A National Study with Machine Learning Insights academic.oup.com/biomedgeron…

Uric acid to high-density lipoprotein cholesterol ratio as a novel biomarker for sarcopenia: a...

AbstractBackground. Sarcopenia is a major age-related health burden. Although the uric acid to high-density lipoprotein cholesterol ratio (UHR) has been li

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Examining the Relevance of Gait Speed Resiliencies to Different Stressors: the ARIC Study academic.oup.com/biomedgeron…

Examining the relevance of gait speed resiliencies to different stressors: the ARIC Study

AbstractBackground. Different stressors may impact physical resilience differently (resiliencies). Objective metrics assessing different stressors’ “releva

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Turning as a single and dual task—associations with alzheimer’s and vascular pathologies in cognitively healthy older people academic.oup.com/biomedgeron…

Turning as a single and dual task—associations with Alzheimer’s and vascular pathologies in...

AbstractBackground. Turning performance is an important and challenging motor activity, with potential relevance in several brain diseases. This study aime

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Olfaction and Muscle Strength in Older Adults: A Longitudinal Study academic.oup.com/biomedgeron…

Olfaction and muscle strength in older adults: a longitudinal study

AbstractBackground. Olfactory impairment is common in older adults and has been linked to weight loss and functional decline. This study aimed to examine w

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Developing and Internally Validating AI-Based Aging Resilience Biomarkers in Non-Human Primates academic.oup.com/biomedgeron…

Developing and internally validating AI-based aging resilience biomarkers in non-human primates

Abstract. Quantifying biological aging is crucial for understanding functional decline before the onset of morbidity. While many accelerated aging and frai

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Frailty and genetics: linking molecular aging to clinical vulnerability academic.oup.com/biomedgeron…

Frailty and genetics: linking molecular aging to clinical vulnerability

Abstract. Aging is a multifactorial process involving cumulative cellular and molecular damage, directly affecting physiological reserve and homeostasis. I

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Correction to: A genome-wide association study identified 10 novel genomic loci associated with intrinsic capacity academic.oup.com/biomedgeron…

Correction to: A genome-wide association study identified 10 novel genomic loci associated with...

This is a correction to: Melkamu B. Beyene, Renuka Visvanathan, Robel Alemu, Beben Benyamin, Rudrarup Bhattacharjee, Habtamu B. Beyene, Olga Theou, Matteo

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