1/2. Don’t think I’ve seen this pattern in rectal mucosa before! HSIL (AIN3) with striking replacement of anorectal crypt epithelium, producing multiple rounded dysplastic crypt profiles on low power. The appearance brought to mind cervical CIN3 with gland/crypt involvement.

#GUpath prostate bx: nice example of "microcystic" pattern prostatic adenocarcinoma (still 3+3) pathologyoutlines.com/topic/…

Stomach H&E Incomplete intestinal metaplasia vs complete intestinal metaplasia. Dr. Montgomery PathCast GIPS piped.video/live/THNxU0XZkMs… #PathX #pathology #PathTwitter

Miliary lung disease occurs when a massive number of pathogens break out of an initial infection site, travel through the bloodstream, and blanket the lungs with thousands of tiny, millet-seed-sized spots This is miliary tuberculosis, but the same principle applies to disseminated histoplasmosis and coccidioidomycosis #pathology #pulmpath #pathbugs #crittersontwitter #yalerosenslidecollection

🧠 Neuropathology quiz: Brain mass — from intraoperative consultation to final workup. 1️⃣ Touch prep 2️⃣ Frozen section 3️⃣ Permanent H&E 4️⃣ IHC What’s your diagnosis, and what stain is shown in image 4?

Spectacular fungal ball, highlighted by GMS

Which organ is it, what's the IHC, and what are the differentials? #PathX

Striking histopathology of a metastatic melanoma that's been nearly entirely destroyed by immunotherapy. All that's left is melanin debris and dead tumor cells.

🔬📸 What are these pretty pink round structures in an adrenal gland 🤔 ~ Can you name them and guess the clinical history❓ #Pathology #PathResidents #GUpath

In this fixed cross section, you can see the mass off the surface on both sides of the tibia, as well as the small adjacent satellite nodule within the soft tissue.

Partially intact fragment of tumor with malignant epithelium detaching away from the central core - Papillary Thyroid Carcinoma. (Thyroid, FNA)

Update in #Spleen #Pathology - Metastases to Spleen; 30 images. #hemepath webpathology.com/images/hema…

“Undifferentiated Carcinoma", living up to its name: when the cells tell you malignancy, but refuse to tell you what they are. (Lung FNA)

“Spindle cell melanoma" metastatic to the lung: when the tumor sheds its familiar face and morphology becomes the trap.” (EBUS FNA)

Take a look at Dr. Mukhopadhyay’s rad-pathology correlation video 👇 ❗️

This mammary myofibroblastoma arose in a man's breast (this lesion is more common in men than women). It co-expressed desmin and CD34; Rb protein loss would be anticipated! Good bread and butter!

CLASSIC and gorgeous cytomorphology - a jumbled capillary network weaving through deceptively bland neuroendocrine cells from an intrathyroidal parathyroid neoplasm (adenoma) - "the vascularity and naked nuclei are the clues". (Thyroid, FNA)

Do you notice anything in that duodenal bx? #PathTwitter #PathX #Pathology

WHAT'S NEW IN COLORECTAL TUMORS (WHO 6TH EDITION 2026) Traditional serrated adenomas (TSA) An adenomatous polyp with any amount of TSA component should be classified as TSA. If it has high grade dysplasia, then call it TSA with high grade dysplasia Pic 2: Polyp with TSA component on the left and tubular adenoma component on the right. How to call it? = TSA Dr. Srivastava GIPS pathcast piped.video/live/mdt3Pr4G1Es… #pathology #PathX