We are collecting cool Pathology spotters & cases in one place. If you have one, tag us. We will feature you! #pathspotter #pathtwitter

United States
PathSpotters retweeted
Primary localized amyloid of the breast #breastpath #PathTwitter #MedTwitter #pathology 馃崗Detected on screening mammography as clusters of calcifications 馃崗 25% do not develop a hematologic disorder or systemic amyloidosis 馃崗Apple-green on polarized light
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Balloon Cell Melanoma
Balloon Cell Melanoma: 馃敩Rare variant of MM in which cells have abundant clear cytoplasm 馃敩IHC: HMB45+,S100+,MelA+ 馃敩DD: balloon cell nevi(lack atypia/mitosis),other clear cell tumors 馃敩Prognosis: similar to other MM types @PathSpotters #PathTwitter #path #derm @ColumbiaPath
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Chronic necrotising aspergillosis
Chronic necrotising aspergillosis is locally invasive is seen in patients with immunodeficiency or chronic lung disease. Aspergilloma is a fungus ball that develops in a pre-existing cavity in the lung parenchyma. Acute angled dichotomous branching hyphae found in necrotic tissue
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Bronchiectasis
Replying to @HermelinMD
鉁匓ronchiectasis. In addition to respiratory complications, children also develop pancreatic insufficiency & lose the exocrine pancreas leading to malabsorption and steatorrhea, as well as GI complications.
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Warthin-like papillary thyroid carcinoma
Warthin-like papillary thyroid carcinoma. 馃敩Papillae lined with oncocytic cells, with prominent lymphocytic infiltration of stalks. Tumor nuclei are enlarged, irregularly sized with grooves and occasional pseudo-inclusions. Background of lymphocytic thyroiditis.
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Dedifferentiated Chondrosarcoma
DEDIFFERENTIATED CHONDROSARCOMA. NB: juxtaposition of lower grade chondrosarcoma with an undifferentiated spindle-pleomorphic cell neoplasm; brisk mitotic activity; necrosis.
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Kikuchi-Fujimoto Disease
REtweet Kikuchi-Fujimoto disease. Necrosis without neutrophils, increased plasmacytoid dendritic cells, CD123 positive
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Aggressive NK/T cell leukemia
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Mucinous metaplasia of the fallopian tube
Mucinous metaplasia of the fallopian tube - Can be associated with Peutz-Jeghers syndrome and mucinous neoplasms at other sites - Should exclude mucinous neoplasia elsewhere in female genital tract/GI #pathresidents #gynpath
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Nodular Melanoma
Nodular melanoma: large聽profusely聽bleeding聽鈥渟kin聽tag"聽present for 3 months聽in聽the intergluteal fold.聽Positive聽for聽S100, Melan A, and HMB聽45.Classic features: dermal-invasive聽melanoma with lack of significant聽radial growth phase (i.e.聽junctional聽component)
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Metastatic Breast IDC with lobular growth pattern
Metastatic breast聽IDC聽with lobular growth聽pattern in the pleural cavity:聽Cytology showed abundant atypical聽cells with聽cannibalism. Cell blocks聽were聽positive聽for MOC31, GATA-3,聽GCFDP-15,聽and聽negative聽for聽mucicarmine,聽ER,聽PR, HER2.
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Multifocal Oncocytoma of Parotid
Multifocal oncocytoma/oncocytosis of parotid. 馃敼multiple nodules, some circumscribed and some not. 馃敼some can be clear cell rich. 馃敼p63 should show an incomplete outer layer around the nests. But wait鈥ren鈥檛 these supposed to be golden brown grossly? See final pic.
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Solitary fibrous tumor/Hemangiopericytoma
Solitary fibrous tumor/Hemangiopericytoma, WHO grade I. Cerebrum, tumorectomy. HE and STAT6. #pathology #neuropath
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