Paediatric oncologist, clinical trials, neuro-oncology, precision medicine.

Sydney
Prof David Ziegler retweeted
Thanks to The @australian for highlighting this research theaustralian.com.au/health/…
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Prof David Ziegler retweeted
Excited to share our latest publication - precision medicine is the right approach for DMG / DIPG! nature.com/articles/s41467-0…
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Excited to share our latest publication - precision medicine is the right approach for DMG / DIPG! nature.com/articles/s41467-0…
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Thanks to The @australian for highlighting this research theaustralian.com.au/health/…
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Heading to the #AACR26 Education Session "Small Patients, Big Data: Making Precision Medicine Work in Pediatric Cancer"? Take a look at this study coauthored by speaker David Ziegler. brnw.ch/21x1IAH @ProfDavidZieg
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And now actually published in open access :) !! rdcu.be/fa3nt
Delighted to share our manuscript - the first look at the epi-transcriptome in DMG! We discovered that RNA methylation is a critical regulator in DMG. nature.com/articles/s41419-0…
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Our lab just published a JoVE video article covering PDX models for paediatric brain cancer. Here’s a quick preview! Link to full video and article: hubs.ly/Q042_QJ40
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Prof David Ziegler retweeted
📰 Discover the special issue of #Daily27 for #ChildhoodCancerDay Read insights from international experts in our two new articles on #childhoodcancerawareness and new advances in the fight against pediatric brain tumors 💛 #EndChildhoodCancer #Oncology #Health #News 👇🧵
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Thanks to 27 Daily for allowing me to share some thoughts on World Childhood Cancer Day
Replying to @Daily27Info
🧵'A New Chapter in the Fight Against Childhood Brain Cancer' 🌍 #InternationalChildhoodCancerDay ✍️ David Ziegler, paediatric oncologist at the @KidsCancerInst 🔗 daily27.info/2026/02/15/a-ne… #EndChildhoodCancer #BrainCancer #Health #News
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Very excited about this paper - new way to shut down transcription in DMG - looking now at clinical translation
Inhibitors of the proteins FACT and BET disrupt transcription in #DiffuseMidlineGlioma and extend survival in mice, hinting this combo can suppress hard-to-target epigenetic drivers of this pediatric cancer. @holly_holliday_ @ProfDavidZieg @KidsCancerInst scim.ag/3ZfoysL
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Prof David Ziegler retweeted
Congrats to the team for our work - on the cover of Science Translational Medicine! One more step forward to find effective treatments for #DIPG. Thanks to all our funders - See details here:
New in @ScienceTM 🧬 On the cover! Our work on diffuse midline glioma (#DMG #DIPG), an incurable paediatric brain cancer driven by epigenetic changes. We asked: Can targeting chromatin slow tumour growth?🔗science.org/doi/10.1126/scit… #ScienceTranslationalMedicineResearch
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Prof David Ziegler retweeted
New in @ScienceTM 🧬 On the cover! Our work on diffuse midline glioma (#DMG #DIPG), an incurable paediatric brain cancer driven by epigenetic changes. We asked: Can targeting chromatin slow tumour growth?🔗science.org/doi/10.1126/scit… #ScienceTranslationalMedicineResearch
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Prof David Ziegler retweeted
Together, these results support dual FACT + BET inhibition as a promising DMG therapy, hitting both tumour-intrinsic vulnerabilities and immune defenses. @KidsCancerInst @UNSW Huge thanks to @aaminahkhan_1, @ProfDavidZieg, @maria_tsoli & all collaborators!
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Prof David Ziegler retweeted
This work was generously supported by grants from @nhmrc, @cancerNSW, @DIPGCollab, @CureStartsNowAU, @KidsCancerProj, @thekca, We Love You Connie Foundation and Levi’s project
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Prof David Ziegler retweeted
Listen to Oprah! Time to book your trip to Australia. #ISPNO2026 instagram.com/reel/DRw5SJ1gG…
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Prof David Ziegler retweeted
Registration and abstract submissions now open for ISPNO 2026! ispno2026.org The world's entire paediatric brain tumour community will be heading Down Under in 2026 - don't miss out!
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Prof David Ziegler retweeted
Join us in Sydney for ISPNO 2026! Experience one of the world’s most vibrant cities, where golden beaches, iconic landmarks & rich First Nations culture await. 🌊🌿 📍 Watch: vimeo.com/1126715713 Registrations open: ispno2026.org #ISPNO2026 #Sydney #SeeAustralia
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You might even get a free koala 🐨
ISPNO 2026 now just over a year away! We will be attending PedSNO - come visit for a chance at complimentary registration!!
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