From Distribution to Dynamics: Advancing Exosome Research with In Vivo Imaging
Exosomes are increasingly being explored in drug delivery, disease research, and therapeutic development. Understanding their in vivo distribution, migration, tissue accumulation, and dynamic behavior is essential for advancing exosome research.
Shenzhen University of Technology is expanding its capabilities in this area with the deployment of the RWD MOIS HT Preclinical In Vivo Optical Imaging System, supporting ongoing research in exosome tracking, biodistribution, and delivery.
From Distribution to Dynamics:
Conventional endpoint-based analyses often require animals to be sacrificed at different time points for tissue collection, making it difficult to continuously monitor changes in the same animal.
In vivo imaging provides a non-invasive approach to longitudinally tracking labeled exosomes, enabling researchers to observe their dynamic behavior within living animals.
With fluorescence and bioluminescence imaging, the MOIS HT supports applications including:
• In vivo tracking – monitoring labeled exosomes across multiple time points.
• Biodistribution – visualizing changes in exosome signals across different tissues and regions.
• Tissue accumulation – assessing where and how exosomes accumulate over time.
• Delivery studies – providing dynamic data to evaluate in vivo delivery performance.
The MOIS HT combines a back-illuminated, high-quantum-efficiency CCD detector with high-sensitivity optical detection, supporting the capture and quantification of weak biological signals. Fluorescence signal separation further helps distinguish target signals from tissue autofluorescence, supporting clearer visualization and more reliable quantitative analysis.
👉 Learn more about the RWD MOIS HT:
rwdstco.com/product-item/sma…
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