Stefan Ruhl@Ruhl_Lab

We study how #glycans in #saliva make #bacteria stick to #teeth

 University at Buffalo, NY, USA
ruhl-lab.org
Joined September 2016
96 Photos and videos
💧💧 #SALIVA ❗️💧💧 The Oral Environment - Oral Microbiology and Immunology - Wiley Online Library onlinelibrary.wiley.com/doi/…

The Oral Environment

This chapter provides an overview of the environment in which oral microbes live. It describes host defense factors that oral microbes face and the mechanisms the microbes use to overcome them to...

onlinelibrary.wiley.com
1
168
💧💧 #SALIVA ❗️💧💧 Multiscale structural evolution of proline-rich protein genes shapes primate salivary defenses Congratulations, Will Aguado and @PetarPajic93 academic.oup.com/mbe/advance…

Multiscale structural evolution of proline-rich protein genes shapes primate salivary defenses

Abstract. Saliva forms the first biochemical interface with the environment, mediating dietary exposure and oral defense. Proline-rich proteins (PRPs) in s

academic.oup.com
1
263
Great meeting ❗️Thanks to the organizers!
ISEMPH@ISEMPH
Aug 12
ISEMPH 2026 in Kiel was a huge success! Thanks to everyone who presented, participated, and especially to the hosts! See you next year in Toronto!
138
🦷🦷 #TEETH 🦷🦷 & 👄 #MOUTH 👄 & 🦠🦠 #MICROBES 🦠🦠 A novel finding by Christian Ahearn important for understanding the mechanisms underlying dental biofilm formation. academic.oup.com/femsle/arti…

Identification of interbacterial adhesion between oral Schaalia species and streptococcal serine-...

Schaalia odontolytica and Schaalia sp. HMT-172 surface proteins bind to streptococcal serine-rich repeat glycoproteins.

academic.oup.com
3
5
158
🦷🦷 #TEETH ❗️🦷🦷 washingtonpost.com/science/2…

A 59,000-year-old tooth reshapes what we know about Neanderthal dentistry

Neanderthals used rock drills to treat an infected tooth, according to a study that pushes back the earliest known evidence of dentistry by more than 40,000 years.

washingtonpost.com
32
500-year-old gold dental bridge is earliest known oral care of its kind in Scotland — and it likely held a fake tooth livescience.com/archaeology/…

500-year-old gold dental bridge is earliest known oral care of its kind in Scotland — and it likely...

Archaeologists discovered the 20-karat-gold dental wire in the lower jaw of a middle-aged man who lived around 500 years ago in Scotland.

livescience.com
1
3
79
This year we went in with a strong team from University at Buffalo School of Dental Medicine @UBSDM @UB and @UofR advocating on Capitol Hill for Oral Science @NIDCR at NIH @AADOCR #FundOralHealth
2
82
Happy to see our new department website going live! 🎆 dental.buffalo.edu/departmen…

Oral Biology

As the first and oldest department of oral biology in a U.S. dental school and the first department to offer a PhD in oral biology, we proudly uphold a legacy of excellence that spans decades. The...

dental.buffalo.edu
2
83
A compelling write-up by Laurie Kaiser of our recent findings about the evolution of 💧💧#SALIVA 💧💧. Proud of @PetarPajic93 who led the investigation with help from @luanelandau. Grateful to Ömer @GokcumenLab, a master of evolutionary genetics. buffalo.edu/ubnow/stories/20…

Tracking evolution of human saliva back to primates

A UB study highlights how evolutionary adaptations to diet and disease may have influenced primate biology, including humans.

buffalo.edu
2
3
1,221
academic.oup.com/gbe/article… 🦷🦷 #TEETH 🥛🥛 #MILK 💧💧 #SALIVA❗️
1
172
🦷🦷 #TEETH❗️🦷🦷
Tied2Teeth@Tied2Teeth
7 Oct 2025
Replying to @Tied2Teeth
From shredders to slicers, from mower to spears… Dinosaur dental diversity mirrored their diets and niches; this adaptability in feeding strategies was likely a major key to their 200 million years of evolutionary success. Credit Image: commons.wikimedia.org/wiki/F…
Picture of phylogeny of main dinosaurs groups.

ALT Picture of phylogeny of main dinosaurs groups.

81
What have 🦷🦷 #TEETH 🦷🦷, 🥛🥛 #MILK 🥛🥛, and💧💧 #SALIVA 💧💧to do with each other? Ask @PetarPajic93 , Luane Landau, and @GokcumenLab ❗️ academic.oup.com/gbe/article…

Saliva Protein Genes in Humans were Shaped During Primate Evolution

Abstract. Genes within the secretory calcium-binding phosphoprotein locus diversified along with the formation of a calcified skeleton in vertebrates, the

academic.oup.com
2
2
190
Stefan Ruhl retweeted
Petar Pajic@PetarPajic93
26 Sep 2025
Link to the paper to read more: doi.org/10.1093/gbe/evaf165 Special thanks to Omer Gokcumen @GokcumenLab and Stefan Ruhl @Ruhl_Lab !

Saliva Protein Genes in Humans were Shaped During Primate Evolution

Abstract. Genes within the secretory calcium-binding phosphoprotein locus diversified along with the formation of a calcified skeleton in vertebrates, the

academic.oup.com
1
1
1
74
🦷🦷 #TEETH ❗️🦷🦷
PNASNews@PNASNews
11 Sep 2025
The Spotted Ratfish, Hydrolagus colliei, is one of a group of fishes called chimaeras whose males sport a unique facial feature: the tenaculum, a club-shaped, cartilaginous appendage covered in teeth. A study investigates these extraoral teeth. In PNAS: ow.ly/pEXn50WVhJJ
Photograph of adult, male H. colliei in Puget Sound. (C) Micro-CT scan of male H. colliei. (G) Segmentation of the adult tenaculum. CREDIT: Photograph used with permission from Tiare Boyes.

ALT Photograph of adult, male H. colliei in Puget Sound. (C) Micro-CT scan of male H. colliei. (G) Segmentation of the adult tenaculum. CREDIT: Photograph used with permission from Tiare Boyes.

53
🦷🦷 #TEETH ❗️🦷🦷
nature
@Nature
3 Sep 2025
Genetic-sequencing techniques have uncovered the oldest host-associated microbial DNA ever recorded — inside samples of teeth and bones from woolly and steppe mammoths. go.nature.com/424UwtE
61
🦷🦷 #TEETH ❗️🦷🦷
Gareth Fraser@garethjfraser
2 Sep 2025
Ever wondered how #sharks produce an unlimited supply of teeth? Our new preprint uncovers the genes within the dental stem cell niche driving lifelong tooth development. "Shark tooth regeneration: RNAseq reveals genes for unlimited dental renewal" 🦈🦷 bit.ly/47kkRHL
1
80
Another gift from Neanderthals and Denisovans: DNA from ancient bones reveals how Indigenous Americans got their mucus | Science | AAAS science.org/content/article/…

DNA from ancient bones reveals how Indigenous Americans got their mucus

Neanderthals and Denisovans passed along gene that provides a sticky shield against germs

science.org
5
19
1,128
Stefan Ruhl retweeted
John Hawks
@johnhawks
23 Aug 2025
Published this week was one of the best evolutionary stories I’ve seen in a while. In a game of “genetic telephone” a 72-kb chunk of Denisovan DNA introgressed to Neanderthals, then slid into modern humans. And it makes mucus. johnhawks.net/p/the-gene-fro…

The gene from Denisovan to Neanderthal to modern mucus

A “genetic sandwich” reveals how a block of DNA entered several populations successively and was affected by natural selection.

johnhawks.net
3
49
152
20,546
Dear Friends, Colleagues, and Followers, I have reached a stage where I decided to take a break from the Twitter/X media platform. I will reconsider my decision after an extended period of time, but if I don't miss anything by then, I will cancel my account. // Stefan
149
Stefan Ruhl retweeted
Massilani Lab@Diyendo
10 Jan 2025
Our Cell Genomics preview “Double or Nothing – Ancient Duplications in the Amylase Locus Drove Human Adaptation” covering Yilmaz F. (@feyza__yilmaz) et al., Science 2024 and Bolognini D. (@davidebolo93) et al., Nature 2024 is now out. massilani-lab.com/new-public…
19
71
3,836
Load more