The Spangler Lab at Johns Hopkins University integrates structural biology, molecular engineering, and translational immunology to design new disease therapies.
Baltimore, MD
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Thrilled to share our new article in @acsnano
on the use of a hydrogel-based platform developed by the lab of @dinodicarlo for immune phenotyping at the single cell scale: doi.org/10.1021/acsnano.4c18…
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Delighted to share our new article in @MolTherapy on novel bispecific VEGF antagonist proteins for treatment of eye diseases:
sciencedirect.com/science/ar…
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Thrilled to share our new collaborative research on CAR NK cell engineering with @BonifantLab just published in JITC:
jitc.bmj.com/content/13/2/e0…
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Excited to share our lab's new review article in @trendscancer, surveying recent work in engineering growth factor systems to advance cancer therapy:
cell.com/trends/cancer/fullt…
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SpanglerLab retweeted
Exciting news! #HopkinsBME research landed the cover of @JCI_insight for September.
A complex approach for antitumor activity: insight.jci.org/articles/vie…
The Cover features study by Elissa Leonard, Jakub Tomala et al. They engineered a cytokine/antibody fusion protein with important implications for future immunocytokine development.
@SpanglerLab @HopkinsMedicine
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So honored to have our cytokine/antibody fusion protein work featured on the cover of @JCI_insight! Huge thanks to Ann Seliger for the beautiful illustration. insight.jci.org/9/18
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Excited to share our latest work by Elissa Leonard, Jakub Tomala, and colleagues on the the design of cytokine/antibody fusion proteins for cancer immunotherapy published in @JCI_insight!
insight.jci.org/articles/vie…
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SpanglerLab retweeted
👀Preview of Ludwig et al.: Sharks give a handle to potent anti-tumor multiparatopic antibodies inducing membrane depletion of PD-L1 by Gordana Wozniak-Knopp and Veronica Natale at @BOKUvienna @acibGmbH dlvr.it/T6znCd
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Congratulations to Seth, Pao, Ben, and team on their new multiparatopic downregulating antibody article in @CellChemBiol! Huge thanks to our fantastic collaborators as well! @hdooley13 @Imaging4Health
doi.org/10.1016/j.chembiol.2…
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Thrilled to share that Dr. Spangler has been promoted to Associate Professor with Tenure in the departments of Biomedical and Chemical & Biomolecular Engineering at Johns Hopkins. Deeply grateful for the trainees, mentors, colleagues, and collaborators who made this all possible!
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The Spangler Lab is deeply honored and grateful to receive a Stage 2 Damon Runyon-Rachleff Innovation Award from the Damon Runyon Cancer Research Foundation @DamonRunyon! damonrunyon.org/news/entries…
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Congratulations to Justyn, Pao, and Ben on their fantastic antibody article out in Annual Review of Chemical and Biomolecular Engineering!
@AnnualReviews
annualreviews.org/doi/10.114…
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Congratulations to Jakub Tomala and Shanelle Cao on their new review article on anti-cytokine antibodies in Journal of Immunology @J_Immunol!
doi.org/10.4049/jimmunol.230…
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SpanglerLab retweeted
Check out my latest article: I’m stuck on how great this research is! linkedin.com/pulse/im-stuck-… via @LinkedIn
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SpanglerLab retweeted
Jan '24 #Workshop #Advances in #Immunoengineering! FREE Registration
jhtie.jhmi.edu/training-upco…
Exciting speakers include:
@scienceempress
@JennyNJiang
@michal_bassani
Dan Campbell
Sharon Gerecht
& more!
@NIBIBgov
@HopkinsMedicine
@HopkinsEngineer
@INBT_JHU
@JHUBME
@TTECJHU
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Congratulations to Luke Tomasovic (@luketomasovic11), Kathy Liu, Dr. Derek VanDyke, and Charina Fabilane on their new review article on IL-2 therapies for autoimmune diseases out in @BioDrugsJournal!
doi.org/10.1007/s40259-023-0…
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Delighted to share recent PhD laureate Dr. Aliyah Silver's new article on engineering a tumor-targeted cytokine/antibody fusion protein in @CellRepMed! Thanks to @JGreenGroup and @jishiharalab for working together with us on this story. doi.org/10.1016/j.xcrm.2023.…
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Congratulations to Derek and Paul on their new article in Journal of Biological Chemistry!
@jbiolchem
doi.org/10.1016/j.jbc.2023.1…
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Congratulations to Derek and Paul on their new article in Journal of Biological Chemistry! @jbiolchem
doi.org/10.1016/j.jaut.2023.…
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