Assistant Professor @ Stanford ChemE synthetic biology, biomolecular engineering synbiogaolab.bsky.social/
Stanford, CA
- Tweets 425
- Following 846
- Followers 3,142
- Likes 538
Have you ever wondered what it would've been like to live in a different kind of society? After a record number of rejections, I'm self-archiving my first attempt at... flash fiction, featuring "Hemingway-esque economy" and "Ishiguro's measured revelation" (if you ask Claude).
1
5
684
Having often dealt with binder-limited projects, we sought a more accessible source for nanobodies than yeast display or llama. Here we introduce Germinal, computationally designing antibody-like binders with such a hit rate that only tens need to be screened for each target.
The ability to design antibodies against any protein of interest has major implications for medicine, biotech, and basic science.
Today, we introduce Germinal, a pipeline for epitope-targeted de novo antibody design achieving 4–22% success rates with efficient experimental validation.
3
10
54
13,166
Thank you for being such a leader and role model, @CarolynBertozzi! Apparently Stanford decides to inspire us more by juxtaposing our paper with your lecture 😅 @Stanford_ChEMH
1
22
So great meeting everyone again at #msbw2022! Here's Eerik sharing RADAR and reminiscing on the first mSBW :)
1
4
57