Structural Virology, Membrane Biology & DNA repair -Publications & NEWS @IOCBPrague uochb.cz/infochem/boura… *tweets by post-doc @dhurvas2007
Prague, Czech Republic
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New preprint alert! #cryoEM #ribosomes #antibiotics *Structure of the Hibernating Francisella tularensis Ribosome and Mechanistic Insights into Its Inhibition by Antibiotics* | Klima & Silhan et al., 2025 doi.org/10.1101/2025.11.25.6…
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@NIVBcz
@IOCBPrague
@EvzenBoura
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The Boura Lab retweeted
👏 Congratulations to the first two recipients of the ComeBack return grants. They are Petra Krafčíková (Bouřa lab) and Lenka Loukotová (Cigler lab).
#IOCBPrague #UOCHB #WomenInScience #ReturnToScience #CzechScience #OPJAK
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AlphaFold database now includes 1.7 million 'homodimers' - comprising two interacting strands of the same molecule
go.nature.com/3NxCOea
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The Boura Lab retweeted
The same western blot image used 23 times in 14 different papers by one Japanese team. The image has been labelled as representing a range of experiments and proteins. This is the most I have ever seen. Perhaps it is a record?
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The Boura Lab retweeted
The Vienna BioCenter PhD program in Molecular BioSciences will offer 25+ fully-funded positions in the Spring Call which is now open. Have a look at what our campus has to offer: vbcphd.at
@IMPvienna @IMBA_Vienna @gmivienna @MaxPerutzLabs @univienna @MedUni_Wien
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The Boura Lab retweeted
Milestone reached: Over 20,000 new structures deposited to the PDB in 2025!
This reflects advances in cryo-EM, high-throughput crystallography, and AI-driven modelling, supported by expert wwPDB biocuration and open data sharing.
Read more: wwpdb.org/news/news?year=202…
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New publication alert 2025!
Alcohol metabolite causes cancer we shed some light how our bodies remove genotoxic damage by studying Fanconi anaemia Slx4-Xpf-Ercc1 nuclease complex Havlíková et al, Commun Biol 2025
doi.org/10.1038/s42003-025-0…
@CzechAcademy
@IOCBPrague
@CharlesUniPRG
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New publication alert 2025!
Structural Insights into Salinosporamide a Mediated Inhibition of the Human 20S Proteasome.
#human #proteasome #inhibitor #salinosporamide #20S
@CzechAcademy @UCSD
@IOCBPrague @EvzenBoura
@PavlaFajt
mdpi.com/1420-3049/30/6/1386
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The Boura Lab retweeted
Japanese researchers develop peptide preventing COVID-19 infections
japantimes.co.jp/news/2025/0…
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Recent collaborative publication 2025!
Ivancová al et., 2025
Enzymatic synthesis of reactive RNA probes containing squaramate-linked cytidine or adenosine for bioconjugations & cross-linking with Lys-containing peptides & proteins.
@hocekm @EvzenBoura
doi.org/10.1038/s42004-024-0…
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New Publication Alert 2025! 🎉
Krejcova, K., Boura, E.
Arch Virol 170, 61 (2025).
Structural basis for broad-spectrum binding of AT-9010 to flaviviral methyltransferases.
doi.org/10.1007/s00705-025-0…
@CzechAcademy @IOCBPrague @NIVBcz @EvzenBoura
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New preprint on Proteasome research!
#proteasomes #inhibitors #Cancer *Structural insights into Salinosporamide A mediated inhibition of the human 20S proteasome*
Sülzen et al., 2025
biorxiv.org/content/10.1101/…
@CzechAcademy @NIVBcz
@IOCBPrague @EvzenBoura @PavlaFajt
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Final updated version: now available online 🎉
Hagen et al., 2025 - Biophysical Chemistry (@sciencedirect @ElsevierConnect) doi.org/10.1016/j.bpc.2025.1…
@EvzenBoura @CzechAcademy @IOCBPrague @NIVBcz
New publication alert 2025!
SPR is a fast and straightforward method to estimate the binding constants of cyclic dinucleotides to their binding partners, such as STING or poxin.
Hagen et al., 2025
#STING #poxin #ITC #SPR
sciencedirect.com/science/ar…
@CzechAcademy @IOCBPrague @NIVBcz
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The Boura Lab retweeted
#research #surfaceplasmonresonance #STING #poxin
SPR is a fast and straightforward method to estimate the binding constants of cyclic dinucleotides to their binding partners, such as STING or poxin (@EvzenBoura) - Biophysical Chemistry: doi.org/10.1016/j.bpc.2025.1…
@TheBouraLab @IOCBPrague @CzechAcademy @NIVBcz
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New publication alert 2025!
SPR is a fast and straightforward method to estimate the binding constants of cyclic dinucleotides to their binding partners, such as STING or poxin.
Hagen et al., 2025
#STING #poxin #ITC #SPR
sciencedirect.com/science/ar…
@CzechAcademy @IOCBPrague @NIVBcz
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The Boura Lab retweeted
We’ve just published our #PhDprojects for 2025/26, offering exciting opportunities in #OrganicChemistry #Biochemistry #CellBiology #MolecularBiology #Bioinformatics #PhysicalChemistry #ChemicalPhysics and more.
🔍 Explore our projects: uochb.cz/en/phd-projects-202…
✍️ Apply for the interview day: uochb.cz/en/call-for-phd-app…
ALT PhD at IOCB Prague. Join our community of 200 PhD students. Registration deadline: 3 March 2025. Interview Day: 20 March 2025.
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The Boura Lab retweeted
Happy New Year from @IOCBPrague and @IOCBBoston! May 2025 bring you new bonds and groundbreaking research!
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New publication alert 2024!
Distinct substrate specificities of the three catalytic
subunits of the Trichomonas vaginalis proteasome. Fajtova et al., 2024
#collaboration #inhibitors #Trichomoniasis
onlinelibrary.wiley.com/doi/…
@PavlaFajt @EvzenBoura
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The festive season is here.. 🍻 Bouřa Lab's Laser Games and IOCB Christmas parties 🎉🎉 Back-to-back 🧑🎄🌲
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The Boura Lab retweeted
🧊 An important day for @IOCBPrague and our research: We’ve opened a new underground building at our campus, designed to house a state-of-the-art #cryoEM center with cutting-edge equipment. Congratulations to everyone involved in this multiyear project!
ALT Opening ceremony of the new building for cryogenic electron microscopy at IOCB Prague. (Photos: Tomáš Belloň/IOCB Prague)
ALT Opening ceremony of the new building for cryogenic electron microscopy at IOCB Prague. (Photos: Tomáš Belloň/IOCB Prague)
ALT Opening ceremony of the new building for cryogenic electron microscopy at IOCB Prague. (Photos: Tomáš Belloň/IOCB Prague)
ALT Opening ceremony of the new building for cryogenic electron microscopy at IOCB Prague. (Photos: Tomáš Belloň/IOCB Prague)
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