Group Leader of the Genome Function Laboratory @TheCrick From 2025, find me over on the other side: bsky.app/profile/gregfindlay… (he/him)
London
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Great to see this out now in @CellGenomics . A few points about what we learned in revisions over on BlueSky:
bsky.app/profile/gregfindlay…
Our latest from @TheCrick, now on @biorxivpreprint:
biorxiv.org/content/10.1101/…
Michael Herger (@HergerMichael) and Christina Kajba jointly led development of a new prime editing platform for testing large numbers of human genetic variants.
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Greg Findlay retweeted
Join us for a PhD! Applications close November 5th. crick.ac.uk/careers-study/va…
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Crick PhD recruitment for fall 2025 is officially open! Please apply to our lab through the Crick application portal if interested. 👇
crick.ac.uk/careers-study/va…
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Greg Findlay retweeted
New from our lab @TheCrick , led by @BetkaRoe. A fun side project that tried to understand what happens when a chaperonin encounters a translating ribosome.
biorxiv.org/content/10.1101/…
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Greg Findlay retweeted
Come join us in making agriculture sustainable at @PhytoformLabs! 🌱We are looking for an R&D scientist with a background in Synthetic biology to join our tools & traits team for precision genome editing 🧬. If you think this could be you, please apply!
linkedin.com/jobs/view/39723…
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Greg Findlay retweeted
So excited that our paper “De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome” is out today in @Nature nature.com/articles/s41586-0…
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(1/4) I’m delighted to announce that our research on RNU4-2 is now out on @Nature . This is an exciting finding that will bring many diagnoses worldwide. We have updated some new results since the preprint: nature.com/articles/s41586-0…
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Greg Findlay retweeted
We are delighted to announce that Professor Edith Heard has been appointed as our new director and chief executive!
Edith, who is currently director-general at @EMBL, will succeed Paul Nurse in leading the Crick from the summer of 2025.
🔗 crick.ac.uk/news/2024-07-09_…
ALT "The Francis Crick Institute has quickly established a global reputation for its work at the frontiers of science. I relish the challenge of building on that work. I also want to pay tribute to Sir Paul Nurse, without whom the Francis Crick Institute would not be the world-leading institution it is today." - Edith Heard
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Greg Findlay retweeted
Want to fully investigate this large dataset beyond classical 2D formats? Go interactively explore the data 👇
vhl-board.onrender.com/
The VHL data can also be searched, visualised, and explored using this awesome SGE visualisation platform made by @ChloeTerwagne:
vhl-board.onrender.com/
Chloé’s code is all on GitHub if you’re interested in viewing and sharing your own data like this. (3/n)
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Massive thanks to all authors, but particularly @ChloeTerwagne, Athina Ganner, @LauraCubitt3, @ReidBrewer3, Dong-Kyu Kim & @Eivakine for key inputs to revisions. And, of course, many thanks to reviewers, @nature_genet, and funders @TheCrick @CRUKresearch (7/n)
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Of course, we hope you read the paper and use the data. Do feel free to reach out with questions on anything from protocol tips to variant classifications.
(8/n)
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Finally, we’re delighted to see this published back-to-back with a massive SGE analysis of BAP1 led by Andrew Waters, @David_J_Adams and co. @sangerinstitute:
nature.com/articles/s41588-0…
So many more variants now readily interpretable, and still more on the way! (9/9)
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Greg Findlay retweeted
Our DNA Typewriter protocol (written by @LiaoHanna, @JShendure, and myself) is out! Thank you @NatureProtocols for writing/editing this with us and having it as this week’s #FeaturedProtocol :-)
#FeaturedProtocol this week from Jay Shendure on using #DNATypewriter (#primeediting-based method) for tracing insertional events bit.ly/4cegahU
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Greg Findlay retweeted
Happy to share this opportunity to join our team. Please apply if you are interested, or re-post if you are not on the look out for a new job crick.wd3.myworkdayjobs.com/…
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Greg Findlay retweeted
Excited to see our work on the development of a platform for pooled screening of genetic variants using prime editing published on @biorxivpreprint: doi.org/10.1101/2024.04.01.5….
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