locked onto the truth, coloring around the edges generously, Christian without explanation. Mysical Union w/ God-yours to grab as close as your heart and mouth.

USA
product launched. now spending my day to find customers and people who want a job selling life insurance on the best dialer in the world lesstime.ai
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Why can’t we just formally declare peace with china and Russia? @POTUS at least a truce? End of hostilities?
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TheHBrand retweeted
We’re building Copilot as a new OS for work that spans every model, every form factor, and every task. Today, we’re announcing our biggest update to Copilot to date, bringing four things together: · Autopilot: proactive and long-running agent built for the enterprise · Code: build apps with Copilot, hosted inside your company’s tenant · Home: Chat + Cowork together · Office: now fully embedded in Copilot (and Copilot embedded in Office, of course!) Plus, you can invoke Copilot in Teams, and we’re introducing Today, a proactive experience that surfaces the most important information from across M365 without needing to ask for it. The way we work is changing and so are our workflows. This update brings AI into that flow, from answering a question, to building an app, to getting work done on your behalf.
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Opus 5.5 is going 138 TPS NOT fast mode. Astra is going 45 TPS... @OpenAIDevs
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TheHBrand retweeted
The last thing you see before Dario blocks your access to Claude
nooo the model is too unsafe to release … its just too sexy haha .. oops I released it lol wyd
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TheHBrand retweeted
🚀🚀
Can our TPUs survive and operate in space? Well, we're going to find out. Project Suncatcher is hitching a ride aboard @SpaceX's Transporter-18 mission, testing a prototype satellite built in partnership with @planet One small step for TPUs....
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my actual night last night. implementing a new 3rd part of production to use Jev to increase product output quality substantially. Jev took one aspect of my product from 82% to 100% quality. the customers noticed!
Save half a million, use 100x the tokens, nbd 💅
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This is unfortunately true. my liberal friends, please pay attention. this isn't a right wing thing. this is a human rights, medical care issue. If you haven't talked to homeless you would believe the false idea that they're hard on luck - 99% of them at LEAST - mental and drug
The NGOs end up increasing the number of homeless people they manage, because that’s the only way to increase their revenue! Incentives drive outcomes. “Homeless” is a propaganda word used to describe people on the street who are mentally ill or severely addicted to drugs. The word implies that this is someone who fell a little behind on their mortgage payment and they’re one job offer away from getting back on their feet, which is obviously false if you’ve ever tried talking to a “homeless” person in SF, LA, NY, Austin or anywhere else. The honest reality is that we need to bring back asylums for extreme mental illness or drug addiction for those who are a serious danger to themselves or others.
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wow that's a lot of GB300. I think these are the ones that are like 10x or more the speed of the previous ones in Colossus 1. rapid and welcome
Replying to @minchoi
Colossus 1 is 150k H100, 50k H200 and 30k GB200. Colossus 2 is 110k GB200 and 440k GB300. Another 220k GB300 will be fully operational next week and another 220k in November. If we get lucky, yet another 220k GB300 by late December.
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I love this
Couldn't be prouder of @PalmerLuckey for winning the Wildfire XPRIZE. In the US alone, wildfires cause over $500 billion in damage every year. It's time to finally take action. Palmer is also joining @moonshots_pod as a judge for the Build with Gemini XPRIZE tomorrow.
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If you think "Opus 5.5 medium" or "Astra medium" is better than MAX, you're wrong. that's all. have a good day
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TheHBrand retweeted
computer (Astra) lights on please. this may be the most extensively detailed & accurate 3d scene ever created by an ai. 400+ hours of Astra
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BREAKING STUDY: Nattokinase Breaks Down SPIKE PROTEIN, AMYLOID MICROCLOTS, BLOOD CLOTS, and SHRINKS ARTERIAL PLAQUE We assembled DECADES of evidence to uncover the powerful MULTI-TARGET EFFECTS of nattokinase: - Degrades spike protein - Breaks down harmful amyloid proteins - Dissolves abnormal amyloid microclots - Breaks down fibrin blood clots - Boosts the body’s natural clot-dissolving system - Shrinks arterial plaque - Lowers blood pressure - Reduces blood-clotting factors and platelet clumping Our new paper, “Proteolytic Targets and Clinical Benefits of Oral Nattokinase: Spike Protein and Amyloid Degradation, Fibrinolysis, and Cardiovascular Risk Reduction,” was produced through a collaboration between The Wellness Company and the McCullough Foundation. It represents one of the most comprehensive evaluations of nattokinase to date, uniquely integrating its proteolytic, cardiovascular, pharmacokinetic, amyloid, and spike-protein literature into a single paper. After oral dosing, nattokinase-related activity shows up in human blood and changes clotting and clot-breakdown markers within hours. Three independent labs have now shown that nattokinase-related enzymes can BREAK DOWN SPIKE PROTEIN in vitro—including purified nattokinase itself. At higher doses, human imaging studies reported about a 36% SHRINKAGE in carotid artery plaque—suggesting the effective range may begin around 6,000 FU/day. Randomized human trials also show modest BLOOD-PRESSURE reductions with nattokinase, with pooled decreases of about 3.5 mmHg systolic and 2.3 mmHg diastolic. And in long-term population studies, higher natto intake was associated with a 25% LOWER RISK of cardiovascular death and a 32% LOWER RISK of stroke death. Nattokinase has been well tolerated across human studies, with no notable adverse events reported across six randomized trials. Even 10,800 FU/day for 12 months was used in a large observational cohort without reported excess bleeding. This inexpensive, orally available enzyme holds immense promise for cardiovascular risk reduction in the post-COVID era. It now deserves large-scale clinical testing for cardiovascular risk reduction and other post-vaccination injury applications. We plan to launch some of these studies shortly. @twc_health @McCulloughFund @P_McCulloughMD @DrHarveyRisch @DrKellyVictory @jathorpmfm @drdrew @PeterGillooly
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i'm very interested in this. I know Jev just came out but I have no loyalty to a bot or a software. if this is better, faster and cheaper I want it so I can layer it in even more
Introducing Contrastive Language Model (CLM): an ultra-fast System One Model trained with a contrastive learning objective that connects states and actions. CLM-8B is pre-trained on internet-scale data and delivers up to 9× faster inference than Jev ⚡ while achieving comparable performance across computer-use, gaming, and tool-calling tasks. With lightweight fine-tuning, CLM-8B sets a new SOTA on challenging agentic coding benchmarks, such as DeepSWE (81.6%) and Terminal-Bench 2.1 (87.6%). In contrast, Jev fails to serve as an effective verifier for these long-horizon tasks. We also build an efficient training and serving infra for CLMs by disaggregating states and actions, allowing their embeddings to be cached and reused independently. This substantially reduces inference latency in settings where the state evolves continuously while the action set remains fixed. Finally, we establish scaling laws for CLMs and show that the test contrastive loss decreases predictably as a power law in training compute, model size, and dataset size. 📄 Blog: contrastive-lm.notion.site 💻 Code: github.com/Contrastive-LM/CL… 🗣️ Discord: discord.gg/5dAQEDJBs 🤗 Data & Models: huggingface.co/Contrastive-L… More details on CLM’s architecture, data recipe, and scaling laws in the thread below 🧵
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TheHBrand retweeted
Meta VR Glasses Coming Spring 2027.
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TheHBrand retweeted
Thanks, Peter! This is the beginning of the end for destructive wildfires. In a country that loses ~$500B every year to wildfires, even tiny gains make for huge savings, to say nothing of the incalculable value of lives and homes.
Congrats to @PalmerLuckey and Anduril for winning the Wildfire XPRIZE - for detecting and suppressing a wildfire within 10 minutes of ignition!
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A 37-year-old man with a rare blood disease was being sent to hospice. An AI model searched thousands of existing drugs and ranked a combination no one had tried for his condition. He responded within a week. He is in remission. The drugs were already on the shelf. The AI model found the match.
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Team humanity. no one should be opposed to this. Thank you Anthropic.
Today we announced the Claude-led discovery of a molecular machine that we suspect could represent a new gene editing mechanism. Its precise function, biotechnological utility (if any), or level of significance is not yet clear, but at minimum it is work I would have been proud to do as a PhD student. The work was done mostly, though not entirely, by Claude: our life sciences team suggested a broad area of research, Claude read through the literature and a bunch of genome data and discovered something interesting, then Claude proposed experiments to verify the discovery and our team carried them out. It’s easy to dismiss this as a one-off or curiosity, but we’ve repeatedly seen a pattern where AI performance in new intellectual domains goes from weak to superhuman in a matter of a few years. In 2023 models struggled to do math at the level of an average high-school student. In 2024 they started to do well on math competitions for the best high-schoolers in the country, in 2025 they started to solve minor open problems, in early 2026 more significant open problems, and in late 2026 they are beginning to solve the top few open problems in all of mathematics. We believe AI for biology is on a similar exponential trend. The main difference between biology and mathematics, of course, is that math can be done purely theoretically, while biology requires experimentation. Some have used this to draw the conclusion that AI’s utility in biology will be limited. We think this is wrong. As we’ve demonstrated today, humans can collaborate with AI to perform the experiments, validate key results in a few weeks and, if necessary, work with the AI to iterate on what they find. Eventually it may even be possible for Claude itself to safely perform the experiments by autonomously controlling lab equipment, with appropriate safeguards in place, but we aren’t doing that today (our lab is also a BSL1/BSL2 facility that doesn't handle materials dangerous to humans). More broadly, biomedical advancement has many stages — from fundamental biology discoveries, to translational research, to drug discovery, clinical trials, and finally the actual delivery of medicines and health care to patients. We are also interested in these later stages, but even simply accelerating the first stage of fundamental biological discoveries has the potential to speed up and broaden the entire pipeline. Improving our understanding of biology and sharpening biologists’ tools can drive forward all of the later stages, for example by identifying new drug targets, finding new therapeutic modalities, allowing for more precise measurement, and speeding up the experimental loop which itself further accelerates our understanding of biology. This will not in itself speed up clinical trial times, but if it succeeds it could greatly increase the number of promising candidates that go into the pipeline — an increase in throughput even though latency remains. In Machines of Loving Grace, I wrote about AI’s potential to “cure most diseases in 5-10 years” — a goal that sounds impossible, but one I believe is just barely possible if AI is applied to every stage of the pipeline. The first step is showing that AI can first help with, and then drive, biological discoveries. Claude’s discovery is the latest in a line of related prior work that goes back decades, beginning with systems like CRISPR, and continuing with discoveries like the bridge recombinase and VIPR in the past few years. Recently, there has been heightened interest in systems based on reverse transcriptase (RT) enzymes, the enzyme underlying the system Claude identified. And most recently, a Stanford team working independently described a novel RT system with an associated non-coding array that is in some ways similar to the one Claude found, though they are distinct systems that evolved independently from each other. I believe that we’re at the very beginning of finding such systems and developing them into powerful tools for biotechnology. I’m proud of the resources Anthropic has invested in accelerating the public benefits of AI through the life sciences, and we’re aiming both to grow our life sciences team and to work with other scientists to extend this approach to a broad range of problems. If you have a proposal for a research collaboration or are interested in joining our life sciences team, please reach out.
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Opus 5.5 on Max is the real next step change. if you have been avoiding Anthropic, just go back now, ignore fable, and use Opus 5.5 on Max and just see what happens. I AM having to talk to it way too much for my liking but they're good questions and without them I guess the model would have ruined things so yea... i'm wrong for not wanting to sit here.
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