The Yaden Lab studies psychedelic & other altered states of consciousness. In the Johns Hopkins Center for Psychedelic & Consciousness Research @JHPsychedelics
Johns Hopkins University
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Yaden Lab retweeted
Meeting with scientists, clinicians, and bioethicists at @JHUBloombergCtr to discuss practical ethical guidelines for clinical applications of psychedelics. Meeting led by @eddietalksdrugs & @Katherine_Chg with @briandavidearp and I glad to see @psychedelethics doing applied work
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Yaden Lab retweeted
The first completely on-site preclinical animal study from @JHPsychedelics.
An immensely valuable collaboration with Division of Behavioral Biology. So grateful that I got to lead it and work with what can only be called the dream team!
Unroll the tweet below for deets 📜
New paper led by @PraachiTiwari, a former postdoc in @TheYadenLab, now faculty at Div of Behavioral Bio & @JHPsychedelics (also w/ @CassieMoorePhD, Brian Jenkins, Elise Weerts, me).
We examined how psilocybin affects a broader range of spontaneous behaviors in rats than HTR...
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Yaden Lab retweeted
New paper led by @PraachiTiwari, a former postdoc in @TheYadenLab, now faculty at Div of Behavioral Bio & @JHPsychedelics (also w/ @CassieMoorePhD, Brian Jenkins, Elise Weerts, me).
We examined how psilocybin affects a broader range of spontaneous behaviors in rats than HTR...
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Yaden Lab retweeted
From 144(!) items, to just 14 plus three stand-alone items.
We validated this using factor analysis (initial factor structure did not replicate), qualitative procedures to ensure participants understand items, and getting near identical results b/w long and short form in trials
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Yaden Lab retweeted
New paper, by me & @r_ehrenkranz (former postdoc at @TheYadenLab, now asst prof of biostats at @NorthwellHealth): We validated & shortened the Persisting Effects Questionnaire (PEQ), used to measure pos and neg changes after psychedelic exp-144 items to 14, w/ 3 stand-alone items
New paper – Validating and Creating a Short-Form of the Persisting Effects Questionnaire: A Measure of Positive and Negative Outcomes from Psychedelic Experiences
The Persisting Effects Questionnaire (PEQ) is a measure of self-reported positive and negative effects from psychedelic experiences. While commonly used, the PEQ has never been formally validated, and is time-intensive and complex for both participants and researchers.
Using a multi-study approach, CPCR researchers created and validated the Persisting Effects Questionnaire – Short Form (PEQ-SF), a scale that is more easily understood and reduces burden for study teams and participants.
Read the paper here: journals.sagepub.com/doi/10.…
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Yaden Lab retweeted
Eddie Jacobs PhD @eddietalksdrugs representing @TheYadenLab, @JHPsychedelics, @psychedelethics–and I think the consensus of many psychedelic scientists–at @FDA
Any clinical application of psychedelics should, at least initially, use safeguards based on the clinical trial context
Representing Dr. David Yaden's (@ExistWell) lab @TheYadenLab at the CPCR & @psychedelethics at @FDA — see Postdoc Eddie Jacobs, PhD (@eddietalksdrugs) from the FDA public hearing this week on the importance of implementing safeguards based on standardized evidence on psychedelic treatments in clinical trials.
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Yaden Lab retweeted
New paper – Validating and Creating a Short-Form of the Persisting Effects Questionnaire: A Measure of Positive and Negative Outcomes from Psychedelic Experiences
The Persisting Effects Questionnaire (PEQ) is a measure of self-reported positive and negative effects from psychedelic experiences. While commonly used, the PEQ has never been formally validated, and is time-intensive and complex for both participants and researchers.
Using a multi-study approach, CPCR researchers created and validated the Persisting Effects Questionnaire – Short Form (PEQ-SF), a scale that is more easily understood and reduces burden for study teams and participants.
Read the paper here: journals.sagepub.com/doi/10.…
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Yaden Lab retweeted
Representing Dr. David Yaden's (@ExistWell) lab @TheYadenLab at the CPCR & @psychedelethics at @FDA — see Postdoc Eddie Jacobs, PhD (@eddietalksdrugs) from the FDA public hearing this week on the importance of implementing safeguards based on standardized evidence on psychedelic treatments in clinical trials.
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Yaden Lab retweeted
Just 3 more weeks to sign up for our CME/CE course! The CPCR faculty led course will provide an evidence-based introduction to psychedelic medicine, covering patient engagement, emerging research, and the future of psychedelic-assisted care. Register at tinyurl.com/jhucme
📚 Earn up to 6.5 CME/CE credits
📅 October 9, 2026 | Online | 8:45am–4:30pm ET
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Yaden Lab retweeted
Went with @TheYadenLab to speak to the @FDA about the rollout of #psychedelics and listen to other stakeholders. 120s speaking time boiled down even further: ...
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Yaden Lab retweeted
He also cited our @JAMAPsych article by our group (w/ Jared Hinkle @MariannaGrazz @sdpnayak me) showing that psychedelics do sometimes result in serious adverse events (4% in neuropsychiatric populations)-important to remember alongside the real benefits
jamanetwork.com/journals/jam…
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Yaden Lab retweeted
In order to adjust safeguards based on data on risks and benefits, evidence needs to be collected - and collected well, that is, in a standardized manner and comparable to other treatments and substances!
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Yaden Lab retweeted
Representing @TheYadenLab at @JHPsychedelics & @psychedelethics at @FDA. Postdoc Eddie Jacobs @eddietalksdrugs spoke to how the evidence on psychedelic treatments comes from clinical trials, so those safeguards should be used for initial roll-out, to be adjusted based on data…
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Yaden Lab retweeted
Interesting discussion prompted by @xphilosopher on our study correlating philosophical views with psychological traits in professional philosophers:
when philosophers indicate they “accept” a view (eg on PhilPapers survey), do they believe it or just defend it? Thoughts?
Many of you will know the famous finding from @ExistWell and Derek Anderson:
Philosophers' views on philosophical questions are not predicted by their personality traits
But why not? I asked Anderson about this, and he had an intriguing suggestion
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philarchive.org/rec/YADTPO-2
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Yaden Lab retweeted
Psychedelic treatments are getting leaner as they approach licensing. Our (@IanRou of @PsyPANglobal, @HattiWells, and @drrosalindwatts) new Perspective in @TheCJPsych argues this gives us (more) reason to pay attention to patients’ social/relational environments🧵
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Yaden Lab retweeted
What should psychedelic science take - and not take - from other disciplines? Join us in celebrating the book launch of The Oxford Handbook of Psychedelic, Religious, Spiritual, and Mystical Experiences on Wed, Aug 5th from 10am-2pm ET. Attend in-person in Washington DC or virtually on Zoom.
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Yaden Lab retweeted
Do you live with chronic low back pain and depression?
You’re not alone. Our research team at Johns Hopkins is studying whether psilocybin may help with pain and mood. If you’d like to learn more or see if you qualify, visit the link below. hopkinspsychedelic.org/backp…
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Yaden Lab retweeted
Dr. David Yaden shares insights and safety considerations for Oregon’s psilocybin services program with the Oregon Capital Chronicle:
oregoncapitalchronicle.com/2…
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Yaden Lab retweeted
The CBG story continues. Here is the latest study from our group @jhucsl
Safety, pharmacodynamics, and pharmacokinetics of oral cannabigerol in healthy adults. sciencedirect.com/science/ar…
No adverse events
⬇️self-reported ratings of Jittery and Actrive at 50 mg
⬇️Calm at 100mg..,
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Yaden Lab retweeted
Great article in Scientific American on the Hopkins Post Psychedelic Difficulties Clinic!
As psychedelic therapies expand, new clinics treat uncommon long-term harms
spklr.io/6019ERHoz
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