Structure of Macromolecular Assemblies Laboratory at CIB-CSIC Interested in Cryo-EM, RNA polymerases and Transcription
Madrid
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Our latest work is now out! Congratulations to the whole team on this publication. Happy reading!
#CIBpapers
The group led by Dr. Carlos Fernández Tornero at @CIB_CSIC, in collaboration with the company @PhrmMar, has revealed key structural features of ecteinascidins binding to DNA.
🔗cib.csic.es/news/research/dn…
cc: @CSIC, @CSICdivulga
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We're hiring! Are you looking for a PhD position in structural biology? We offer a fully-funded 4 year contract to study basic processes connected to transcription. If you're interested in joining us in sunny Madrid, get in touch with us!
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Have you ever heard of 11-subunit RNA polymerase I? We describe a structure lacking A12 in addition to A49/A34.5!
We are happy to share our latest work on RNA polymerase I! We continued our #CryoEM study of its stalling mechanism, this time at abasic lesions, and uncovered interesting Pol I configurations.
Read more at @biorxivpreprint: biorxiv.org/content/10.1101/…
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We are happy to share our latest work on RNA polymerase I! We continued our #CryoEM study of its stalling mechanism, this time at abasic lesions, and uncovered interesting Pol I configurations.
Read more at @biorxivpreprint: biorxiv.org/content/10.1101/…
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El pasado jueves estuvo Carlos en el #GoogleCloudSummitMadrid compartiendo nuestros últimos resultados, obtenidos con el apoyo de Alphafold, sobre complejos enzimáticos del parásito de la enfermedad del sueño: pubmed.ncbi.nlm.nih.gov/3859…
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La publicación de #AlphaFold3 nos trae muchas oportunidades en el campo, especialmente para los que trabajamos en interacciones proteína-ácido nucleico. Carlos da unas pinceladas sobre su gran potencial, pero también sus posibles limitaciones, en @abc_es: abc.es/ciencia/carlos-fernan…
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We are very excited to share the structure of the T. brucei MCC and a putative activation mechanism! Out now in structure:
cell.com/structure/fulltext/…
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¡Damos la bienvenida a la nueva directora y vicedirectores! Agradecemos su labor al equipo saliente y tenemos muchas ganas de seguir trabajando de cerca estos años.
Damos la bienvenida a la Dra Pilar S. Testillano como nueva directora del @CIB_CSIC. La acompañarán como parte de su equipo, los vicedirectores Carmen Gil y Antonio Romero.
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Esta tarde Adrián y Carlos van a presentar algunos de nuestros últimos avances en el congreso ibérico de microscopía electrónica, en Braga. No os los perdáis a las 14:30! #MFS2023
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This paper made the cover of the latest issue of The FEBS Journal!
febs.onlinelibrary.wiley.com…
Breaking news! "Conserved GTPase mechanism in bacterial FtsZ and archaeal tubulin filaments" - a snapshot on the conserved GTPase mechanism in bacteria and archea.
febs.onlinelibrary.wiley.com…
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For our part, we have really enjoyed listening to the interesting stories that were shared in these past days, and visiting Jaén was a blast. Until next time! #OddPols2023
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We finish the scientific sessions today with Sonia's talk about our latest @NatureComms paper on Pol III and Ty1 and some very exciting discussion with @pascale_lesage and the audience! #OddPols2023
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Closing off the second poster session along with the great work of @Olga_ocg @ibfg_es lab! There's a lot of promising work being shared in these sessions :) #OddPols2023
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A beautiful scenery to close off the first day of #OddPols2023!
Very nice social activity of the #odddpols23 community with a sightseeing of the city, and an olive oil tasting activity at the Magdalena's church thanks to the collaboration with @FundacionCRJ and the parish church. @TorneroLab
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We're very excited to be at #OddPols2023 in Jaén!! Looking forward to all the great talks :)
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A congress all about odd pols! Don't miss it!!
Carlos Fernández-Tornero (@CIB_CSIC), is a co-organizer of the OddPols 2023, which will be held in Jaén between May 30-Jun 2. This scientific congress is framed in the field of #transcription and it is organized for the first time in Europe.
More info ➡️cib.csic.es/news/research/ci…
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Además, en el último episodio de "A Hombros de Gigantes" @rne, @searavalero incluyó testimonios de Carlos Fernández-Tornero sobre el mismo tema, los "genes saltarines": rtve.es/play/audios/a-hombro…
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¡Ya podéis leer en la página del CSIC un pequeño artículo sobre nuestra última publicación! Nueva información sobre la inserción de "genes saltarines" en el genoma -->csic.es/es/actualidad-del-cs…
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Check it out! We just published a new story on Pol III and Ty1 integrase on nature communications:
Very happy to share this novel story from our labs: Cryo-EM structures of Ty1 IN-Pol III complexes revealing new determinants of Ty1 targeting and functional impact of on Pol III activity that may increase the probability of Ty1 integration
nature.com/articles/s41467-0…
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Una fantástica colaboración de nuestro laboratorio en el @CIB_CSIC con Pascale Lesage (@pascale_lesage), Juan Reguera (@jreguera) y Joel Acker (@I2BCParisSaclay)
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