Our TITAN-SR paper is out in J Clin Epidemiol.
A biomedical BERT ensemble for systematic-review title/abstract screening — developed and externally validated against active learning and LLM chatbots.
doi.org/10.1016/j.jclinepi.2…
#SysRev #MedTwitter #EvidenceSynthesis
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What TITAN-SR is.
Ensemble of PubMedBERT + BioLinkBERT, trained on ~763k human screening decisions from real reviews. One job: include/exclude.
Not a rented chatbot with a clever prompt — a specialist classifier.
coresr.ai
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Why that matters for systematic reviews.
Chatbots can flip on the same abstract across runs.
TITAN-SR is deterministic: same input → same output every time (agreement 1.0). Reproducibility is the floor, not a bolt-on feature.
coresr.ai
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Safety margin you can set.
It returns calibrated probabilities. Threshold fixed on held-out data to hold recall ≥0.99 — and that operating point transfers to new records.
You set the bar once. It carries.
doi.org/10.1016/j.jclinepi.2…
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Headline from the paper: the BERT ensemble outperformed active learning and LLM chatbots for title/abstract screening on external validation.
Screening is classification, not conversation. Build the specialist.
coresr.ai
#SystematicReview #AI
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TITAN-SR powers screening inside CoreSR — search → RoB → extraction → NMA/GRADE → draft.
Paper: doi.org/10.1016/j.jclinepi.2…
Platform: coresr.ai
Thanks to Zeraatkar, Granton, Busse, Rochwerg, Guyatt.
#CoreSR #JClinEpi
Sep 22, 2026 · 2:42 PM UTC
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