Our TITAN-SR paper is out in J Clin Epidemiol. A biomedical BERT ensemble for systematic-review title/abstract screening — developed and externally validated against active learning and LLM chatbots. doi.org/10.1016/j.jclinepi.2… #SysRev #MedTwitter #EvidenceSynthesis
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What TITAN-SR is. Ensemble of PubMedBERT + BioLinkBERT, trained on ~763k human screening decisions from real reviews. One job: include/exclude. Not a rented chatbot with a clever prompt — a specialist classifier. coresr.ai
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Why that matters for systematic reviews. Chatbots can flip on the same abstract across runs. TITAN-SR is deterministic: same input → same output every time (agreement 1.0). Reproducibility is the floor, not a bolt-on feature. coresr.ai
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Safety margin you can set. It returns calibrated probabilities. Threshold fixed on held-out data to hold recall ≥0.99 — and that operating point transfers to new records. You set the bar once. It carries. doi.org/10.1016/j.jclinepi.2…
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Headline from the paper: the BERT ensemble outperformed active learning and LLM chatbots for title/abstract screening on external validation. Screening is classification, not conversation. Build the specialist. coresr.ai #SystematicReview #AI
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TITAN-SR powers screening inside CoreSR — search → RoB → extraction → NMA/GRADE → draft. Paper: doi.org/10.1016/j.jclinepi.2… Platform: coresr.ai Thanks to Zeraatkar, Granton, Busse, Rochwerg, Guyatt. #CoreSR #JClinEpi

Sep 22, 2026 · 2:42 PM UTC

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