The latest updates in brain science at UT Southwestern's O'Donnell Brain Institute.
Dallas, TX
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Interested in helping define the future of memory research?
The Program in Memory Longevity is recruiting a tenure-track Assistant or Associate Professor to help advance our understanding of memory and its disruption in aging and disease.
Learn more: bit.ly/4Az3eQy
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OBI Investigator, Sebastian Choi, is a 2026 recipient of the Suh Kyungbae Foundation (SUHF) Young Investigator Award. The award is the most prestigious junior faculty recognition for Korean biomedical scientists. Learn more about Dr. Choi's research: schoilab.org/
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"Squishy brain swag" is one of our many talents 😉
So much fun talking to first graders about the wonders of the human brain at @ghcougars today 🧠🎉🥳 and special thanks to @UTSWBrain for the squishy brain swag!
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UT Southwestern O'Donnell Brain Institute retweeted
ALT group photos of our APPs in Neurological Surgery
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You can learn about brain computer interfaces, what they do, and the patients who can benefit from BCI at a presentation next Friday, Sep 18. Speakers: Dr. Cecile Verbaarschot, Dr. Nader Pouratian, Dr. Babu Welch, and #BCI users. More details and register: bit.ly/4ytdrvQ
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OBI Investigator, Dr. Chen Liu, & team identify a brain signaling pathway that appears to drive the substantial weight gain associated with #clozapine, a drug for treatment resistant #schizophrenia. The findings could lead to a way to reduce clozapine's metabolic side effects.
New paper today in @NatureComms with Roger Cone’s group @UMLifeSciences: we identify an MC4R–Kir7.1 pathway contributing to clozapine-induced weight gain, and show it can be targeted without diminishing clozapine’s activity in an antipsychotic assay. bit.ly/4qWH0nk 1/🧵
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Drs. Brad Lega and Dr. Genevieve Konopka co-led research that shows deep brain stimulation strengthens and reshapes the building blocks of thoughts and memories. The findings could lead to more targeted and effective therapies for cognitive issues.
bit.ly/4wp58jv
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Dr. Pedro Rosa-Neto will lead the UTSW North Texas Alzheimer's Disease Research Center. The NT-ADRC supports researchers developing novel treatments for #Alzheimer's, enhances collaborations among researchers, and provides community education. bit.ly/3SdbvZ7
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@UTSWMedCenter is the No. 1 hospital in DFW for the 10th year in a row in @usnews hospital rankings. @UTSWNeurology & @UTSWNeurosurg are in the top 10 nationwide. The rankings reflect the exceptional commitment of our care teams and those who support them. bit.ly/4hNOOoF
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Dr. Amyn Habib co-led research with @UABNews scientists that suggests treating #glioblastoma with a class of drugs known as EGFR inhibitors makes the cancer more sensitive to chemotherapy. Learn how the findings could lead to a new treatment strategy. bit.ly/4pfxQS2
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Discoveries from two OBI Investigators are featured in the new issue of @ScienceMagazine. Dr. Sam McBrayer tracks a missing metabolite in a rare childhood brain disorder. Dr. Attila Losonczy sheds light on the dendritic tree's link to learning and memory. bit.ly/4fsC5VG
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Last Friday, we hosted MD/PhD students from institutions around the country at this year's OBI Physician-Scientist Symposium. The students gave talks on their research that included topics like traumatic brain injury, ALS, and risk/reward. Thank you to the speakers and attendees.
ALT MD/PhD students talk about their research at the O'Donnell Brain Institute Physician Scientist Symposium.
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Research from @attila_losonczy Lab found that dendrites, the branchlike structures that extend from neurons, act as minicomputers in the brain, independently processing information. The research is a paradigm shift in current models of learning and memory. bit.ly/4yshHwD
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The Food and Drug Administration has approved two groundbreaking blood-biomarker tests for patients 55 and older with #dementia symptoms. Dr. Brendan Kelley & Dr. Marc Diamond say the tests could fundamentally change the clinical approach to Alzheimer's. bit.ly/4gEDniM
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Registration is open for the UT System Brain Research Summit: Focus on Dementia and Related Neurodegenerative Diseases. OBI Director, Dr. William Dauer, and UTSW faculty Drs. Pedro Rosa-Neto, Marc Diamond, Tarek Rajji, and Jiang He are among the speakers.
bit.ly/4yqTI0Y
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Congratulations to Dr. Naghmeh Kasbi and Dr. Thandiwe Chavula who were awarded O'Donnell Brain Institute travel grants. They presented their original research at scientific conferences last month. The awards support travel for trainees working with OBI Investigators.
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What an accomplishment!
Congrats to @UTSW MSTP student Haley Moore, Ph.D., hooded by @bradlega for completing her thesis, "Cell type specific mechanisms of neuromodulation in the human temporal cortex ex vivo" (next July she'll add the M.D.)! @UTSWMedCenter @UTSWBrain #Neurosurgery
ALT Photo of Dr. Haley Moore being hooded at her Ph.D. graduation ceremony at UT Southwestern by Dr. Brad Lega
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OBI Investigators, Joseph Takahashi, Ph.D., and Carla Green, Ph.D., found that limiting food intake to a consistent daily eating window significantly improved health span in mice. The findings suggest meal timing could be part of a healthy aging strategy. bit.ly/4gr5qlJ
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