starting a cloud lab for assembling genes. first external contributor @pylabrobot, started team autom8 @retrobio_

you can just acquire hamilton STARs with a 10x markdown at bankruptcy auctions
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384x isopropanol precipitation plasmid minipreps in 5.5 fully automated hours. built with @pylabrobot
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What humanity is able to observe is defined by the instruments available to make those observations. This robot is building "a telescope" that will help observe types of autoimmunity never-yet looked for and create a more complete synthetic human proteome.
96-plasmid yeast transformation and 384-spot plating across 4 SBS agar plates for clonal purification. solved by @pylabrobot in 3.25 hours rfc.geneticassemblies.com/rf…
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96-plasmid yeast transformation and 384-spot plating across 4 SBS agar plates for clonal purification. solved by @pylabrobot in 3.25 hours rfc.geneticassemblies.com/rf…
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industrial automators: take note
i'm convinced that i can automate all of factorio using language models. so far, i created a mod within factorio that reads map and inventory data. right now, i'm training llama3 to make good early game decisions. i'll probably make this a series, wish me luck :)
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as I've been saying, generic models + PLR will be sufficient for very strong ai scientists
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Very excited to announce the PyLabRobot Cookbook from the Chory Lab! This cookbook showcases many usage examples and design patterns that should help you get started writing PyLabRobot code quickly. I strongly recommend this cookbook to anyone interested in lab automation!
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Check out the PyLabRobot cookbook made by @wasserstein_rao and @chorye: chory-lab.github.io/plr-cook…
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3.5 hour miniprep solved by @pylabrobot
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list-price enjoyers pay $0.1 per pipette tip
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plate cameras are an underrated way to teach your robot what’s going on inside the well it’s pipetting
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SF Bankruptcy Auction: bid $10 on desks discover the lot is for 50 desks > nobody else bids now you have to move 50 desks.
posting our desk quotes because nobody does this SF: $8,000 desks $2,000 installation $2,000 after-hours installation $2,000 union labor $3,500 expedited delivery = $17,500, 1 month setup China: $8,000 desks $200 installation (Taskrabbit) $0 shipping = $8,200, 4 days setup
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(8/13) Serial transplantation asks whether stem cells can rebuild one blood system, make more stem cells (self-renew), and then rebuild another. A blood transfusion supplies mature cells for a limited time, but a true HSC graft establishes the source that continuously produces new blood and immune cells. Together, these grafts persisted through nearly 10 months of continuous blood production in vivo.
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I’m excited to share the first paper from my PhD research at @RetroBio_ (and my first paper as first author) - now on bioRxiv! Can we take adult human cells, turn them into blood-forming stem cells, and build a new blood system that is both functional and molecularly young? Our preprint: biorxiv.org/content/10.64898…
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Engrafted human iHSCs retain their youthful epigenetic age in vivo despite differentiation and prolonged transplantation.
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I wrote about the call by frontier labs to start regulating DNA synthesis. I, and many lab biologists, think this would be damaging to American biotech. You can read my thoughts in core memory.
The good doctor came in hot today. corememory.com/p/america-can…
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Set is ready @ElonMusk We built it 25min from downtown Austin and can shoot anytime in the next 7 days on 1h notice. Humanity is on the verge of becoming a multi-planet species and spacefaring civilization. My goal with this interview is to help people viscerally feel what that future is going to look like and get everyone excited to help build it.
I guess this is a good time to announce we are currently in the process of building a set for an interview with Elon. Will be finished next month and should be legendary. Elon - lmk if you're in
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ben ray retweeted
My second interview with @JimBelosic, Founder of @SendCutSend. 0:15 Beating China in manufacturing requires scale 1:10 Automation is not a magic bullet 2:12 Scaling profitably 4:31 Delivering a great customer experience 8:44 Why SCS raised $110M 11:20 Expectations are promises 15:33 Increasing speed and capacity 18:46 Focusing on customers 22:20 Frugality and generosity 25:06 Creating The Anything Factory 26:33 3pm is the new midnight 27:49 Figuring out the next bottleneck 30:37 Finding buildings with enough power 35:21 Lowering prices 37:36 Gambling to turn on factories faster 39:03 Aim for perfection and you’ll end up at excellence 40:04 Maintaining a maniacal sense of urgency through impatience 41:30 Seeding SCS DNA at new factories 43:08 Solving challenges 45:32 Finding great capital partners 48:40 Focus on customer pain 51:59 Learning from Home Depot 54:16 Bringing manufacturing back to America 55:11 Building capacity creates demand 57:01 Handling demand surges 58:21 Being default skeptical and sensing bullsh*t 1:00:27 Getting back to building
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the HighRes MicroSpin is now supported in PLR our second centrifuge after the Agilent VSpin great first PR @claudioreiter! also thanks @_benray and @koeng101!
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