Yale School of Medicine researchers reviewed 80 studies. GLP-1 drugs may ease chronic pain by reshaping gut microbes and suppressing neuroinflammation, though direct human proof of this pathway is still limited. mdpi.com/2072-6643/18/19/312…

GLP-1 Receptor Agonists, Gut Microbiota, and Chronic Pain: Nutritional Signaling at the Gut–Brain...

Background/Objectives: Chronic pain affects more than one in five adults worldwide and is increasingly conceptualized as a disorder of the gut–brain axis. Gut microbial dysbiosis, characterized by...

mdpi.com

Sep 25, 2026 · 4:21 PM UTC

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