Brain Communications is the #OA sister journal to @Brain1878. We aim to publish robust translational neuroscience studies.
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Have you read an outstanding paper published in Brain Communications during 2025? Take note of it for the Early Career Researcher Paper Prize! Nominations are Open! #ecr #paperprize #neuroscience
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Fujita et al. report that serial MRI up to 15 years reveals marked individual differences in brain volume loss among cognitively normal adults, including rapid-atrophy and atrophy-resistant phenotypes linked to modifiable lifestyle factors.
Read it at 馃憠buff.ly/eec4u3P
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Rhymes et al. report that ciliary neurotrophic factor selectively slows the retrograde transport of signalling endosomes in motor neurons in vivo, highlighting how neurotrophic factors regulate axonal transport and motor neuron connectivity.
Read it at 馃憠buff.ly/jfwxif1
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What Kafka鈥檚 Metamorphosis reveals about consciousness without communication? In his essay, Demas uses Gregor Samsa鈥檚 example to explore the limits of observable behaviour as a measure of consciousness.
Read it at 馃憠buff.ly/4vwMY2D
#neuroscience #braincommunications
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Meet Prof Tiago Outeiro, Professor at Newcastle University and Director of the Department of Experimental Neurodegeneration at the University Medical Center Goettingen 馃憢
He studies the molecular basis of neurodegenerative disorders such as Alzheimer鈥檚 and Parkinson鈥檚 disease.
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Thompson et al. report the generation and characterization of novel gene-edited mice expressing the human superoxide dismutase 1 (SOD1) gene and carrying the pathogenic SOD1A5V mutation associated with amyotrophic lateral sclerosis.
Read it at 馃憠buff.ly/J8mz8dt
#ALS
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Orlando et al. show that heart rate variability is preserved in people with Parkinson鈥檚 disease receiving an acute dose of atomoxetine, supporting a safe cardiovascular profile for the drug.
Read it at 馃憠buff.ly/hvluO1e
#neuroscience #braincommunications
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Falconer et al. report that dynamic functional connectivity predicts treatment response in post-stroke aphasia with higher temporal variability, greater community stability, and time spent in high-modularity state predicting greater gains.
Read it at 馃憠buff.ly/x3goq2v
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Lukyova et al. give an overview of the genetic background of Alzheimer鈥檚 disease in the era of next-generation sequencing, highlighing mechanisms that may explain missing heritability and the potential of multi-omics for precision medicine.
Read it at 馃憠buff.ly/tJgmAVp
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Sintini et al. report that MRI and 18F-FDG PET principal components diagnostic outperformed tau-PET, with the highest sensitivity for the semantic variant of primary progressive aphasia and progressive supranuclear palsy.
Read it at 馃憠buff.ly/lLfZKxN
#neuroscience
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Meier et al. found that increase in white matter volume, diffusivity and inositol, and abnormal magnetization transfer indicate pre-symptomatic white and grey matter involvement in asymptomatic adolescent adrenoleukodystrophy patients.
Read it at 馃憠buff.ly/TbzGb2P
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Kapadia et al. highlight that the study by Bechkos et al. (2026) independently corroborate previous evidence that electrical stimulation reduces 伪-synuclein oligomerisation in Parkinson鈥檚 disease models.
Read it at 馃憠buff.ly/c3RWM5j
#neuroscience #braincommunications
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Meet Alfred Kongnyu Njamnshi, a Professor of Neurology and Neuroscience at the University of Yaound茅 I and the founder of Brain Research Africa Initiative (BRAIN)馃憢
He researchers sleep and neurocognitive disorders associated with parasitic infections, HIV and stroke.
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Zoellin et al. show that autologous haematopoietic stem cell transplantation is associated with reduced retinal tissue loss in relapsing-remitting multiple sclerosis, with baseline inner nuclear layer thickness predicting better outcomes.
Read it at 馃憠buff.ly/qTHPDO4
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Pini et al. review developmental biomarker changes, proposing that increased p-tau217 and glial fibrillary acidic protein in Alzheimer'鈥檚 disease may reflect unresolved adaptive brain programmes rather than toxic responses.
Read it at 馃憠buff.ly/epphj5D
#neuroscience
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Leveraro et al. report that patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder show altered functional brain organization despite preserved cognition.
Read it at 馃憠buff.ly/BOaMba0
#neuroscience #braincommunications
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Conti et al. report that impaired awareness of visual hallucinations in Lewy body disease involves reduced resting-state connectivity between right visual association and prediction-error systems.
Read it at 馃憠buff.ly/ItuMXvA
#neuroscience #braincommunications
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Xiong et al. report that a deep learning model using susceptibility-weighted MRI of the substantia nigra and adjacent structures predicts motor outcome after subthalamic nucleus deep brain stimulation in Parkinson鈥檚 disease.
Read it at 馃憠buff.ly/oLYnHD2
#neuroscience
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Norouzi et al. studied periodic and aperiodic resting-state features in Parkinson鈥檚 patients across six EEG and MEG datasets, finding elevated alpha power, slower alpha peak frequency, and higher aperiodic offset and exponent.
Read it at 馃憠buff.ly/ouVad3F
#neuroscience
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Keute et al. report that verbal and visuospatial working memory outcomes after deep brain stimulation in Parkinson鈥檚 disease were linked to baseline cortical activity and stimulation-related spectral changes.
Read it at 馃憠buff.ly/IVZQIgn
#neuroscience
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Braun et al. report that human synucleinopathy is associated with astroglial water channel aquaporin-4 mislocalization and glymphatic clearance of 伪-synuclein is impaired in a mouse model with loss of perivascular aquaporin-4.
Read it at 馃憠buff.ly/KfcwH7V
#neuroscience
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